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Author Details

John B Harley
US Department of Veterans Affairs Medical Center
1956
479
95
PMIDPaper TitleJournal TitlePublished Year
37949200Association between systemic lupus erythematosus and myasthenia gravis: A population-based National Study.Clin Immunol2024
36746961Author Correction: Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.Nat Commun2023
37799268Modeling of horizontal pleiotropy identifies possible causal gene expression in systemic lupus erythematosus.Front Lupus2023
37337107Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.Nat Genet2023
34605217Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles.Arthritis Rheumatol2022
35769482Regulatory Architecture of the RCA Gene Cluster Captures an Intragenic TAD Boundary, CTCF-Mediated Chromatin Looping and a Long-Range Intergenic Enhancer.Front Immunol2022
35720322Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals.Front Immunol2022
35388006Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery.Nat Commun2022
36601554The US Department of Veterans Affairs Science and Health Initiative to Combat Infectious and Emerging Life-Threatening Diseases (VA SHIELD): A Biorepository Addressing National Health Threats.Open Forum Infect Dis2022
36160011Haplotype-specific chromatin looping reveals genetic interactions of regulatory regions modulating gene expression in 8p23.1.Front Genet2022
35251022A High Prevalence of Anti-EBNA1 Heteroantibodies in Systemic Lupus Erythematosus (SLE) Supports Anti-EBNA1 as an Origin for SLE Autoantibodies.Front Immunol2022
34906510Reanalysis of eMERGE phase III sequence variants in 10,500 participants and infrastructure to support the automated return of knowledge updates.Genet Med2022
34380996Genetic association of primary nonresponse to anti-TNFα therapy in patients with inflammatory bowel disease.Pharmacogenet Genomics2022
33272962Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus.Ann Rheum Dis2021
33712590Global discovery of lupus genetic risk variant allelic enhancer activity.Nat Commun2021
33669337Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression.J Clin Med2021
33667396Response to Li and Hopper.Am J Hum Genet2021
34467602Validation of low-coverage whole-genome sequencing for mitochondrial DNA variants suggests mitochondrial DNA as a genetic cause of preterm birth.Hum Mutat2021
33941608Medical Records-Based Genetic Studies of the Complement System.J Am Soc Nephrol2021
33982894Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis.Arthritis Rheumatol2021
34086673Novel EDGE encoding method enhances ability to identify genetic interactions.PLoS Genet2021
33060314Relationship Between Genetic Risk and Age of Diagnosis in Systemic Lupus Erythematosus.J Rheumatol2021
30685201Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen.Cytokine2020
33426398Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk.Kidney Int Rep2020
32758450Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk.Am J Hum Genet2020
32981348Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.Circulation2020
32307929Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome-Wide Association Study and Inverse Variance-Weighted Meta-Analysis.Arthritis Rheumatol2020
31515129Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model.J Autoimmun2020
31447229CNV Association of Diverse Clinical Phenotypes from eMERGE reveals novel disease biology underlying cardiovascular disease.Int J Cardiol2020
30423114Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.Hum Mol Genet2019
31695690Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis.Front Immunol2019
29904099Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis.Genes Immun2019
31217170Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals.Ann Rheum Dis2019
31215789Complete Tracheal Ring Deformity. A Translational Genomics Approach to Pathogenesis.Am J Respir Crit Care Med2019
31311600GWAS and enrichment analyses of non-alcoholic fatty liver disease identify new trait-associated genes and pathways across eMERGE Network.BMC Med2019
31022184Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians.PLoS Genet2019
29195081Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].Clin Immunol2018
29912393A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.Hum Mol Genet2018
29804502Less than 7 hours of sleep per night is associated with transitioning to systemic lupus erythematosus.Lupus2018
30046115Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.Nat Commun2018
30096841Trans-Ethnic Mapping of <i>BANK1</i> Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.Int J Mol Sci2018
30085094Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.Hum Mol Genet2018
29669943Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis.JCI Insight2018
29662164Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity.Nat Genet2018
29531773Unique clinical characteristics, autoantibodies and medication use in Native American patients with systemic lupus erythematosus.Lupus Sci Med2018
29126118Decentralized and reproducible geocoding and characterization of community and environmental exposures for multisite studies.J Am Med Inform Assoc2018
27283331Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.Ann Rheum Dis2017
28409015Use of SLICC criteria in a large, diverse lupus registry enables SLE classification of a subset of ACR-designated subjects with incomplete lupus.Lupus Sci Med2017
28118528Clinical and Serologic Features in Patients With Incomplete Lupus Classification Versus Systemic Lupus Erythematosus Patients and Controls.Arthritis Care Res (Hoboken)2017
29149219Characterization and classification of lupus patients based on plasma thermograms.PLoS One2017
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Cincinnati Children's Hospital Medical Center
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University of Texas Southwestern Medical Center
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University of Cincinnati College of Medicine
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Vanderbilt University
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