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Author Details

James C Cross
University of Calgary
1987
130
64
PMIDPaper TitleJournal TitlePublished Year
36859534Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease.Nat Commun2023
33397192Exploration of genetic factors resulting in abnormal disease in cattle experimentally challenged with bovine spongiform encephalopathy.Prion2021
32966295Lack of head sparing following third-trimester caloric restriction among Tanzanian Maasai.PLoS One2020
31751309Blastocyst transfer in mice alters the placental transcriptome and growth.Reproduction2020
31917811Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction.PLoS One2020
29949779Fine-Tuned and Cell-Cycle-Restricted Expression of Fusogenic Protein Syncytin-2 Maintains Functional Placental Syncytia.Cell Rep2018
30042384Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta.Cell Res2018
28717241Sca-1 identifies a trophoblast population with multipotent potential in the mid-gestation mouse placenta.Sci Rep2017
29091755Fine-Tuned and Cell-Cycle-Restricted Expression of Fusogenic Protein Syncytin-2 Maintains Functional Placental Syncytia.Cell Rep2017
26972897Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development.Am J Obstet Gynecol2016
27018791Chronic Protein Restriction in Mice Impacts Placental Function and Maternal Body Weight before Fetal Growth.PLoS One2016
27062876Adaptability and potential for treatment of placental functions to improve embryonic development and postnatal health.Reprod Fertil Dev2016
26906492Gene Amplification: Trophoblast Giant Cells Use All the Tricks.Curr Biol2016
25499676Three-dimensional cultures of trophoblast stem cells autonomously develop vascular-like spaces lined by trophoblast giant cells.Dev Biol2015
26269505Pregnancy Hyperglycemia in Prolactin Receptor Mutant, but Not Prolactin Mutant, Mice and Feeding-Responsive Regulation of Placental Lactogen Genes Implies Placental Control of Maternal Glucose Homeostasis.Biol Reprod2015
25648353Role of mutation and pharmacologic block of human KCNH2 in vasculogenesis and fetal mortality: partial rescue by transforming growth factor-β.Circ Arrhythm Electrophysiol2015
24485853Development of the hemochorial maternal vascular spaces in the placenta through endothelial and vasculogenic mimicry.Dev Biol2014
25329693Endometrial VEGF induces placental sFLT1 and leads to pregnancy complications.J Clin Invest2014
24784435More of a good thing or less of a bad thing: gene copy number variation in polyploid cells of the placenta.PLoS Genet2014
23610556A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta.PLoS Biol2013
24074862Mutation in folate metabolism causes epigenetic instability and transgenerational effects on development.Cell2013
23911935The basic helix-loop-helix transcription factor Hand1 regulates mouse development as a homodimer.Dev Biol2013
23954203The transcriptional co-repressor TLE3 regulates development of trophoblast giant cells lining maternal blood spaces in the mouse placenta.Dev Biol2013
23665443Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.Gene Expr Patterns2013
22434868The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation.Development2012
21693515A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia.Development2011
21839735Ablation of Tpbpa-positive trophoblast precursors leads to defects in maternal spiral artery remodeling in the mouse placenta.Dev Biol2011
21972064Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.Dev Dyn2011
19876834Development and function of trophoblast giant cells in the rodent placenta.Int J Dev Biol2010
19036882Prolactin receptor is required for normal glucose homeostasis and modulation of beta-cell mass during pregnancy.Endocrinology2009
19716815Activin promotes differentiation of cultured mouse trophoblast stem cells towards a labyrinth cell fate.Dev Biol2009
19777589Neural stem cell self-renewal requires the Mrj co-chaperone.Dev Dyn2009
18448564Early patterning of the chorion leads to the trilaminar trophoblast cell structure in the placental labyrinth.Development2008
18776147Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling.Development2008
18948620Homozygous missense N629D hERG (KCNH2) potassium channel mutation causes developmental defects in the right ventricle and its outflow tract and embryonic lethality.Circ Res2008
18662396Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus.BMC Genomics2008
18616428The evolution, regulation, and function of placenta-specific genes.Annu Rev Cell Dev Biol2008
17210791Rb is critical in a mammalian tissue stem cell population.Genes Dev2007
17379301Growth factors and trophoblast differentiation--workshop report.Placenta2007
17369066Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase.Mol Genet Metab2007
17289015Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta.Dev Biol2007
17287753Lentiviruses to the placental rescue.Nat Biotechnol2007
17409114The Mrj co-chaperone mediates keratin turnover and prevents the formation of toxic inclusion bodies in trophoblast cells of the placenta.Development2007
17502352Transcriptional repressor erf determines extraembryonic ectoderm differentiation.Mol Cell Biol2007
17512504Dilated cardiomyopathy is associated with reduced expression of the cardiac sodium channel Scn5a.Cardiovasc Res2007
16251749Phenotypic analysis of the mouse placenta.Methods Mol Med2006
16770948Nutritional influences on implantation and placental development.Nutr Rev2006
16916377Branching morphogenesis during development of placental villi.Differentiation2006
16478604Placental function in development and disease.Reprod Fertil Dev2006
16542720Placental morphology: from molecule to mother -- a dedication to Peter Kaufmann -- a review.Placenta2006
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Collaborators

University of California San Francisco
Co-authored papers 7
Gottfried Schatz Research Center, Medical University of Graz
Co-authored papers 3
Co-authored papers 2
Institute of Child Health.
Co-authored papers 2
University of British Columbia
Co-authored papers 2
The Hospital for Sick Children
Co-authored papers 2
Harvard Medical School
Co-authored papers 1
University of Calgary
Co-authored papers 1
Princess Maxima Center for Pediatric Oncology
Co-authored papers 1
Hollings Cancer Center, Medical University of South Carolina
Co-authored papers 1
American Medical Informatics Association, Oregon Health and Science University, Oregon State University, University of Colorado Anschutz Medical Campus, University of North Carolina at Chapel Hill, University of Wisconsin-Madison
Co-authored papers 1
Air Quality Modelling and Integration Research Unit
Co-authored papers 1
Co-authored papers 1
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
The University of Iowa College of Nursing.
Co-authored papers 1
Co-authored papers 1
The Hospital for Sick Children
Co-authored papers 1
Stony Brook University
Co-authored papers 1
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University Avenue R988
Co-authored papers 1
Co-authored papers 1
The Babraham Institute
Co-authored papers 1
University of Wisconsin-Madison
Co-authored papers 1
BioMedical Center, University of Iceland
Co-authored papers 1
the University of Iowa Carver College of Medicine
Co-authored papers 1
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 1
Cellular Dynamics International Inc.
Co-authored papers 1