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Author Details

Guo-Cheng Yuan
Dana-Farber Cancer Institute, Harvard School of Public Health
2000
136
61
PMIDPaper TitleJournal TitlePublished Year
37162846Identifying Quantitatively Differential Chromosomal Compartmentalization Changes and Their Biological Significance from Hi-C data using DARIC.Res Sq2023
37833630Identifying quantitatively differential chromosomal compartmentalization changes and their biological significance from Hi-C data using DARIC.BMC Genomics2023
37071996Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation.Dev Cell2023
36624845Distinct niche structures and intrinsic programs of fallopian tube and ovarian surface epithelial cells.iScience2022
33361330Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling.Proc Natl Acad Sci U S A2021
33657376Tracing cell-type evolution by cross-species comparison of cell atlases.Cell Rep2021
33685491Giotto: a toolbox for integrative analysis and visualization of spatial expression data.Genome Biol2021
33649594Transcription factor competition at the γ-globin promoters controls hemoglobin switching.Nat Genet2021
33514509Immunosuppressive Myeloid Cells Induce Nitric Oxide-Dependent DNA Damage and p53 Pathway Activation in CD8<sup>+</sup> T Cells.Cancer Immunol Res2021
33731942Author Correction: Transcription factor competition at the γ-globin promoters controls hemoglobin switching.Nat Genet2021
33505024Integrated spatial genomics reveals global architecture of single nuclei.Nature2021
34591592Single-cell nuclear architecture across cell types in the mouse brain.Science2021
34526084Mapping the evolving landscape of super-enhancers during cell differentiation.Genome Biol2021
34599004Advances in spatial transcriptomic data analysis.Genome Res2021
34716321Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture.Nat Commun2021
34413306Author Correction: Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation.Nat Commun2021
34353350Community-wide hackathons to identify central themes in single-cell multi-omics.Genome Biol2021
33941591Inhibition of CDK4/6 Promotes CD8 T-cell Memory Formation.Cancer Discov2021
34244724CUT&amp;RUNTools 2.0: a pipeline for single-cell and bulk-level CUT&amp;RUN and CUT&amp;Tag data analysis.Bioinformatics2021
34290256Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation.Nat Commun2021
34281603Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19.Genome Med2021
33971932SpatialDWLS: accurate deconvolution of spatial transcriptomic data.Genome Biol2021
32334526GiniClust3: a fast and memory-efficient tool for rare cell type identification.BMC Bioinformatics2020
32001672Two faces of bivalent domain regulate VEGFA responsiveness and angiogenesis.Cell Death Dis2020
32084389Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient.Cell Stem Cell2020
31883968CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.Cancer Cell2020
32817427Enhancer dependence of cell-type-specific gene expression increases with developmental age.Proc Natl Acad Sci U S A2020
30670628A dynamic and integrated epigenetic program at distal regions orchestrates transcriptional responses to VEGFA.Genome Res2019
31801909Discovery of specialized NK cell populations infiltrating human melanoma metastases.JCI Insight2019
31659164A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers.Nat Commun2019
31500663CUT&amp;RUNTools: a flexible pipeline for CUT&amp;RUN processing and footprint analysis.Genome Biol2019
31299886RESCUE: imputing dropout events in single-cell RNA-sequencing data.BMC Bioinformatics2019
31211692TGFβ signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome.J Clin Invest2019
31409898LSD1 suppresses invasion, migration and metastasis of luminal breast cancer cells via activation of GATA3 and repression of TRIM37 expression.Oncogene2019
31292159Molecular Profiling Establishes Genetic Features Predictive of the Efficacy of the p110β Inhibitor KIN-193.Cancer Res2019
31278265Accurate estimation of cell-type composition from gene expression data.Nat Commun2019
31391581BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells.Nature2019
30988284CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation.Nat Commun2019
31015418Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM.Nat Commun2019
30981959Estimating Sample-Specific Regulatory Networks.iScience2019
30911168Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH.Nature2019
28736268Differential connectivity of gene regulatory networks distinguishes corticosteroid response in asthma.J Allergy Clin Immunol2018
30002873Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters.Cell Discov2018
30242271Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor.Nat Commun2018
30143676Integrative epigenomic analysis in differentiated human primary bronchial epithelial cells exposed to cigarette smoke.Sci Rep2018
29849139Author Correction: High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.Nature2018
30404000Revealing the Critical Regulators of Cell Identity in the Mouse Cell Atlas.Cell Rep2018
30371680Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data.Nat Biotechnol2018
30566873Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer.Cell Rep2018
29474909Mapping the Mouse Cell Atlas by Microwell-Seq.Cell2018
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Collaborators

Stuart H Orkin
Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School
Co-authored papers 42
Luca Pinello
Co-authored papers 37
Qian Zhu
Boston Children's Hospital
Co-authored papers 11
Ruben Dries
Boston University School of Medicine
Co-authored papers 11
William T Pu
Boston Children's Hospital, Harvard Medical School
Co-authored papers 10
Daniel E Bauer
Co-authored papers 10
John Quackenbush
Harvard T. H. Chan School of Public Health
Co-authored papers 9
Qing Ma
Boston Children's Hospital
Co-authored papers 7
Pingzhu Zhou
Boston Children's Hospital
Co-authored papers 5
Nathanael S Gray
Harvard Medical School
Co-authored papers 5
Sara P Garcia
Co-authored papers 4
Bin Zhou
The Central Hospital of Shaoyang
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Edwin K Silverman
Brigham and Women's Hospital
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Peter S Hammerman
Novartis Institutes for BioMedical Research
Co-authored papers 3
Yukio Nakamura
RIKEN BioResource Research Center
Co-authored papers 3
Jonghwan Kim
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Bing Zhang
Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University
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Deng Pan
College of Plant Protection, Southwest University
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Daniel S Day
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Yingchun Liu
Co-authored papers 3
Feng Zhang
Massachusetts Institute of Technology, USA Broad Institute
Co-authored papers 2
Guillaume Lettre
Co-authored papers 2
Paul Robson
Co-authored papers 2
Ophir Shalem
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Curtis Huttenhower
Broad Institute of MIT and Harvard
Co-authored papers 2
Oliver J Rando
University of Massachusetts Chan Medical School
Co-authored papers 2
Huafeng Xie
South China University of Technology
Co-authored papers 2
John A Stamatoyannopoulos
Altius Institute for Biomedical Sciences
Co-authored papers 2
Marc A Kerenyi
Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
David M Sabatini
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 2
Release 1.2