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Author Details

Derek van der Kooy
University of Toronto
1977
294
86
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35114904Neural Plasticity in the Ventral Tegmental Area, Aversive Motivation during Drug Withdrawal and Hallucinogenic Therapy.J Psychoactive Drugs2023
37551982Fate Specification of GFAP-Negative Primitive Neural Stem Cells and Their Progeny at Clonal Resolution.Stem Cells Dev2023
34963197Administration of BDNF in the ventral tegmental area produces a switch from a nicotine-non-dependent D1R-mediated motivational state to a nicotine-dependent-like D2R-mediated motivational state.Eur J Neurosci2022
35878038Arrestin-mediated desensitization enables intraneuronal olfactory discrimination in <i>Caenorhabditis elegans</i>.Proc Natl Acad Sci U S A2022
34151227A defined subset of clonal retinal stem cell spheres is biased to RPE differentiation.iScience2021
33494791Glucocorticoid agonists enhance retinal stem cell self-renewal and proliferation.Stem Cell Res Ther2021
33725584Stable oxime-crosslinked hyaluronan-based hydrogel as a biomimetic vitreous substitute.Biomaterials2021
34717744Activation of adult mammalian retinal stem cells in vivo via antagonism of BMP and sFRP2.Stem Cell Res Ther2021
34651637A microfluidic platform enables comprehensive gene expression profiling of mouse retinal stem cells.Lab Chip2021
32150654Segregation of caffeine reward and aversion in the rat nucleus accumbens shell versus core.Eur J Neurosci2020
32691994The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury.Stem Cells Transl Med2020
32971001Parental Bias Has Benefits.Neuron2020
32791386Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration.Biomaterials2020
30472119Dual embryonic origin of the mammalian enteric nervous system.Dev Biol2019
31776378Lineage tracing reveals the hierarchical relationship between neural stem cell populations in the mouse forebrain.Sci Rep2019
31776253β2* nAChRs on VTA dopamine and GABA neurons separately mediate nicotine aversion and reward.Proc Natl Acad Sci U S A2019
31884669Induction of Rod and Cone Photoreceptor-Specific Progenitors from Stem Cells.Adv Exp Med Biol2019
31371455A Receptor Tyrosine Kinase Plays Separate Roles in Sensory Integration and Associative Learning in <i>C. elegans</i>.eNeuro2019
30898844Cell competition during reprogramming gives rise to dominant clones.Science2019
30840351Expansion of retinal stem cells and their progeny using cell microcarriers in a bioreactor.Biotechnol Prog2019
30787354Analysis of Mutants Suggests Kamin Blocking in C. elegans is Due to Interference with Memory Recall Rather than Storage.Sci Rep2019
30362188Mutations in the guanylate cyclase gcy-28 neuronally dissociate naïve attraction and memory retrieval.Eur J Neurosci2018
30713997Exogenous Neural Precursor Cell Transplantation Results in Structural and Functional Recovery in a Hypoxic-Ischemic Hemiplegic Mouse Model.eNeuro2018
30265796Single-Cell Tumbling Enables High-Resolution Size Profiling of Retinal Stem Cells.ACS Appl Mater Interfaces2018
30453152Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells.Stem Cell Res2018
28733998Quiescent Oct4<sup>+</sup> Neural Stem Cells (NSCs) Repopulate Ablated Glial Fibrillary Acidic Protein<sup>+</sup> NSCs in the Adult Mouse Brain.Stem Cells2017
28498560Deletion of α5 nicotine receptor subunits abolishes nicotinic aversive motivational effects in a manner that phenocopies dopamine receptor antagonism.Eur J Neurosci2017
28378435A single administration of the hallucinogen, 4-acetoxy-dimethyltryptamine, prevents the shift to a drug-dependent state and the expression of withdrawal aversions in rodents.Eur J Neurosci2017
28494434P-Cadherin is necessary for retinal stem cell behavior in vitro, but not in vivo.Stem Cell Res2017
26946195Targeted activation of primitive neural stem cells in the mouse brain.Eur J Neurosci2016
26408450EphB2 reverse signaling regulates learned opiate tolerance via hippocampal function.Behav Brain Res2016
27134075Corrigendum to "EphB2 reverse signaling regulates learned opiate tolerance via hippocampal function" [Behav. Brain Res. 300 (2016) 85-96].Behav Brain Res2016
26773663Injectable hydrogel promotes early survival of induced pluripotent stem cell-derived oligodendrocytes and attenuates longterm teratoma formation in a spinal cord injury model.Biomaterials2016
26972950Enrichment of Oligodendrocyte Progenitors from Differentiated Neural Precursors by Clonal Sphere Preparations.Stem Cells Dev2016
25392245Diabetes enhances the proliferation of adult pancreatic multipotent progenitor cells and biases their differentiation to more β-cell production.Diabetes2015
26116542A proposed resolution to the paradox of drug reward: Dopamine's evolution from an aversive signal to a facilitator of drug reward via negative reinforcement.Neurosci Biobehav Rev2015
25848752Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse.Nat Genet2015
25981414A Hyaluronan-Based Injectable Hydrogel Improves the Survival and Integration of Stem Cell Progeny following Transplantation.Stem Cell Reports2015
24023036Surfaceome profiling reveals regulators of neural stem cell function.Stem Cells2014
25402857VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation.Nat Neurosci2014
24899712BDNF signaling in the VTA links the drug-dependent state to drug withdrawal aversions.J Neurosci2014
24936468Primitive neural stem cells in the adult mammalian brain give rise to GFAP-expressing neural stem cells.Stem Cell Reports2014
24553116The aggregation and inheritance of damaged proteins determines cell fate during mitosis.Cell Cycle2014
24705878Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.EMBO Mol Med2014
24050115Notch signaling induces retinal stem-like properties in perinatal neural retina progenitors and promotes symmetric divisions in adult retinal stem cells.Stem Cells Dev2014
24192139The neural stem cell lineage reveals novel relationships among spermatogonial germ stem cells and other pluripotent stem cells.Stem Cells Dev2014
22889305The generation of definitive neural stem cells from PiggyBac transposon-induced pluripotent stem cells can be enhanced by induction of the NOTCH signaling pathway.Stem Cells Dev2013
24058869Entwined engrams: The evolution of associative and non-associative learning.Worm2013
24244203Oct4 is required ~E7.5 for proliferation in the primitive streak.PLoS Genet2013
23843349Bone morphogenetic proteins and secreted frizzled related protein 2 maintain the quiescence of adult mammalian retinal stem cells.Stem Cells2013
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Collaborators

The Hospital for Sick Children
Co-authored papers 7
Queen's University
Co-authored papers 5
University of Toronto Division of Neurosurgery and Spinal Program
Co-authored papers 5
Co-authored papers 4
University of Toronto
Co-authored papers 3
University of Toronto
Co-authored papers 3
University of Toronto
Co-authored papers 3
University of Toronto
Co-authored papers 2
Nanjing Agricultural University
Co-authored papers 2
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 2
University of Toronto
Co-authored papers 2
University of California
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
University of Toronto
Co-authored papers 2
University of Toronto
Co-authored papers 2
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 2
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 2
University of Manitoba
Co-authored papers 2
York University
Co-authored papers 1
Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences
Co-authored papers 1
IRCCS Casa Sollievo della Sofferenza, University of Milano-Bicocca
Co-authored papers 1
ETH Zurich
Co-authored papers 1
University of Rochester School of Medicine & Dentistry
Co-authored papers 1
a division of The Scripps Research Institute La Jolla
Co-authored papers 1
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University of Toronto, 1 King's College Circle
Co-authored papers 1
University of Toronto
Co-authored papers 1
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