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Author Details

Sam John
National Cancer Institute
1990
67
44
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
32840769END-seq: An Unbiased, High-Resolution, and Genome-Wide Approach to Map DNA Double-Strand Breaks and Resection in Human Cells.Methods Mol Biol2021
32840769END-seq: An Unbiased, High-Resolution, and Genome-Wide Approach to Map DNA Double-Strand Breaks and Resection in Human Cells.Methods Mol Biol2021
32057297Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity.Elife2020
32057297Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity.Elife2020
28784182Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters.Epigenetics Chromatin2017
28784182Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters.Epigenetics Chromatin2017
27443740Replication fork stability confers chemoresistance in BRCA-deficient cells.Nature2016
27443740Replication fork stability confers chemoresistance in BRCA-deficient cells.Nature2016
27680696Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells.Nature2016
27680696Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells.Nature2016
25689118New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes.J Cell Physiol2015
25689118New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes.J Cell Physiol2015
25677181Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing.Genome Res2015
26257180Role of DNA Methylation in Modulating Transcription Factor Occupancy.Cell Rep2015
26257180Role of DNA Methylation in Modulating Transcription Factor Occupancy.Cell Rep2015
25677181Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing.Genome Res2015
24196351Minireview: Conversing with chromatin: the language of nuclear receptors.Mol Endocrinol2014
25486465Tumor promoting role of the DNA damage response.Cell Cycle2014
24317492Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions.Nat Struct Mol Biol2014
24196351Minireview: Conversing with chromatin: the language of nuclear receptors.Mol Endocrinol2014
24185839Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH.Nat Methods2014
25486465Tumor promoting role of the DNA damage response.Cell Cycle2014
24317492Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions.Nat Struct Mol Biol2014
24185839Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH.Nat Methods2014
23805837Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding.BMC Genomics2013
23821440Genome-scale mapping of DNase I hypersensitivity.Curr Protoc Mol Biol2013
23805837Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding.BMC Genomics2013
23803465Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level.Cancer Res2013
23793028DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements.Nat Genet2013
23665916C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements.EMBO J2013
23821440Genome-scale mapping of DNase I hypersensitivity.Curr Protoc Mol Biol2013
23665916C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements.EMBO J2013
23803465Reprogramming the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level.Cancer Res2013
23793028DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements.Nat Genet2013
22407764The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer.EMBO Mol Med2012
22734930Rapid genome-scale mapping of chromatin accessibility in tissue.Epigenetics Chromatin2012
22955618An expansive human regulatory lexicon encoded in transcription factor footprints.Nature2012
22955617The accessible chromatin landscape of the human genome.Nature2012
22407764The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer.EMBO Mol Med2012
23176727Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.BMC Genomics2012
23176727Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.BMC Genomics2012
22955618An expansive human regulatory lexicon encoded in transcription factor footprints.Nature2012
22955617The accessible chromatin landscape of the human genome.Nature2012
22734930Rapid genome-scale mapping of chromatin accessibility in tissue.Epigenetics Chromatin2012
21258342Chromatin accessibility pre-determines glucocorticoid receptor binding patterns.Nat Genet2011
21258342Chromatin accessibility pre-determines glucocorticoid receptor binding patterns.Nat Genet2011
21471403Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements.Genome Res2011
21427703Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis.EMBO J2011
21726817Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding.Mol Cell2011
21835447Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism.Cell2011
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Collaborators

National Cancer Institute, National Institutes of Health
Co-authored papers 39
Altius Institute for Biomedical Sciences
Co-authored papers 15
National Institute on Aging, National Institutes of Health
Co-authored papers 13
National Cancer Institute, National Institutes of Health
Co-authored papers 13
Institute of Genetics and Molecular Medicine, The University of Edinburgh
Co-authored papers 10
Center for Cancer Research, National Cancer Institute
Co-authored papers 9
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 8
University of Washington
Co-authored papers 8
University of Washington
Co-authored papers 7
Altius Institute for Biomedical Sciences
Co-authored papers 6
NCI Center for Bioinformatics, National Cancer Institute
Co-authored papers 5
University of Washington
Co-authored papers 4
Altius Institute for Biomedical Sciences
Co-authored papers 4
Altius Institute for Biomedical Sciences
Co-authored papers 4
Altius Institute for Biomedical Sciences
Co-authored papers 4
Laval University Cancer Research Center
Co-authored papers 4
University of Kentucky
Co-authored papers 3
Co-authored papers 3
Altius Institute for Biomedical Sciences
Co-authored papers 3
Altius Institute for Biomedical Sciences
Co-authored papers 3
University of Washington School of Medicine
Co-authored papers 3
University of Washington
Co-authored papers 3
Centre Hospitalier Universitaire (CHU) de Quebec-Universite Laval Research Center
Co-authored papers 3
Bristol Medical School, University of Bristol
Co-authored papers 3
Institute for Systems Genetics, NYU School of Medicine
Co-authored papers 3
Oncode Institute, Netherlands Cancer Institute
Co-authored papers 2
Altius Institute for Biomedical Sciences
Co-authored papers 2
Altius Institute for Biomedical Sciences
Co-authored papers 2
Altius Institute for Biomedical Sciences
Co-authored papers 2
Altius Institute for Biomedical Sciences
Co-authored papers 2