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Author Details

Kathryn M Monroe
Denali Therapeutics Inc.
2009
23
19
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36823473Author Correction: Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.Nat Metab2023
37557076Cleaning crew: Soluble TREM2 mops up complement.Immunity2023
36635496A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models.Nat Neurosci2023
35019161Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.EMBO J2022
34450028Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.Cell2021
33619376Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.Nat Metab2021
33758401Microglia clean up toxic lipids in multiple sclerosis.Nat Neurosci2021
32514138Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia.Nat Neurosci2020
31902528TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.Neuron2020
33096024Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer's Disease.Neuron2020
32154671Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.EMBO Mol Med2020
28329768Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.Nature2017
26321639Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells.Cell Rep2015
24356113IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV.Science2014
24356306Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.Nature2014
23707065The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.Cell Rep2013
23796903Mummy, A UDP-N-acetylglucosamine pyrophosphorylase, modulates DPP signaling in the embryonic epidermis of Drosophila.Dev Biol2013
21098106The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides.Infect Immun2011
21947006STING is a direct innate immune sensor of cyclic di-GMP.Nature2011
21703540NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways.Immunity2011
20482555Induction of type I interferons by bacteria.Cell Microbiol2010
19652017A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP.J Exp Med2009
19936053Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila.PLoS Pathog2009
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Collaborators

Christian Haass
German Center for Neurodegenerative Diseases (DZNE) Munich
Co-authored papers 6
Zhiyuan Yang
Gladstone Institute of Virology and Immunology
Co-authored papers 4
Gilad Doitsh
University of California san francisco
Co-authored papers 4
Warner C Greene
Gladstone Institute of Virology, USA University of California san francisco
Co-authored papers 4
Laralynne Przybyla
University of California san francisco
Co-authored papers 3
Xin Geng
1] Gladstone Institute of Virology and Immunology
Co-authored papers 3
Christian Klose
Institut fur Werkstoffkunde (Materials Science), Leibniz Universitat Hannover
Co-authored papers 2
Peter W Hunt
Co-authored papers 2
Nicholas E Propson
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Cathal Mahon
Denali Therapeutics Inc.
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Daniel A Portnoy
University of California berkeley
Co-authored papers 1
Raymond J Pickles
Marsico Lung Institute, University of North Carolina-Chapel Hill
Co-authored papers 1
Bradley F Boeve
Mayo Clinic Rochester
Co-authored papers 1
Katherine A Fitzgerald
Co-authored papers 1
Adam L Boxer
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 1
Howard J Rosen
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 1
Priya Ranjan
Pondicherry University
Co-authored papers 1
Marco Prinz
Co-authored papers 1
Release 1.2