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Author Details

Laura J Niedernhofer
University of Minnesota
1987
174
61
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38051584Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia.JCI Insight2024
35015337Targeting cellular senescence with senotherapeutics: senolytics and senomorphics.FEBS J2023
37291596Aging and chronic inflammation: highlights from a multidisciplinary workshop.Immun Ageing2023
37154858In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.Aging (Albany NY)2023
37347719TP53/p53 Facilitates Stress-Induced Exosome and Protein Secretion by Adipocytes.Diabetes2023
37400722Spatial mapping of cellular senescence: emerging challenges and opportunities.Nat Aging2023
36809340Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.J Clin Invest2023
36734200Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy.Aging Cell2023
36865244<i>In vitro</i> and <i>in vivo</i> effects of zoledronate on senescence and senescence-associated secretory phenotype markers.bioRxiv2023
36198912COVID-19 and cellular senescence.Nat Rev Immunol2023
34498278Extending human healthspan and longevity: a symposium report.Ann N Y Acad Sci2022
35432317The Role of DNA Repair in Immunological Diversity: From Molecular Mechanisms to Clinical Ramifications.Front Immunol2022
35694561PodoCount: A Robust, Fully Automated, Whole-Slide Podocyte Quantification Tool.Kidney Int Rep2022
35363946Targeted clearance of p21- but not p16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity.Aging Cell2022
35968782Epigenetics, DNA damage, and aging.J Clin Invest2022
36239841Cellular Senescence in Obesity and Associated Complications: a New Therapeutic Target.Curr Diab Rep2022
36170431Targeting Cellular Senescence with Senotherapeutics: Development of New Approaches for Skin Care.Plast Reconstr Surg2022
36170430Cellular Senescence in Aging, Tissue Repair, and Regeneration.Plast Reconstr Surg2022
35974106A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.Nat Commun2022
35912854Cellular senescence: a key therapeutic target in aging and diseases.J Clin Invest2022
35015744Chronic HIV Infection and Aging: Application of a Geroscience-Guided Approach.J Acquir Immune Defic Syndr2022
32348501Strategies to Prevent or Remediate Cancer and Treatment-Related Aging.J Natl Cancer Inst2021
37117627Rare genetic coding variants associated with human longevity and protection against age-related diseases.Nat Aging2021
36846190Molecular Damage in Aging.Nat Aging2021
33493548Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1<sup>d/-</sup> mice.Metabolism2021
33512317DNA damage-how and why we age?Elife2021
33728821Mesenchymal stem cell-derived extracellular vesicles reduce senescence and extend health span in mouse models of aging.Aging Cell2021
34734460Novel small molecule inhibition of IKK/NF-κB activation reduces markers of senescence and improves healthspan in mouse models of aging.Aging Cell2021
34375437Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era.J Am Geriatr Soc2021
34484303Case Report: Identification of a Heterozygous XPA c.553C&gt;T Mutation Causing Neurological Impairment in a Case of Xeroderma Pigmentosum Complementation Group A.Front Genet2021
34656616Recent advances in the discovery of senolytics.Mech Ageing Dev2021
34531331SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3.Aging (Albany NY)2021
34103349Senolytics reduce coronavirus-related mortality in old mice.Science2021
34076366Ending a diagnostic odyssey: Moving from exome to genome to identify cockayne syndrome.Mol Genet Genomic Med2021
34015525A conversation with Judith Campisi: Leader in the field of aging research.Ageing Res Rev2021
34066966The Role of Senescent Cells in Acquired Drug Resistance and Secondary Cancer in BRAFi-Treated Melanoma.Cancers (Basel)2021
33981041An aged immune system drives senescence and ageing of solid organs.Nature2021
34363464Role of Cellular Senescence in Type II Diabetes.Endocrinology2021
34197020Genetic signature of human longevity in PKC and NF-κB signaling.Aging Cell2021
33406219Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged Mice.J Gerontol A Biol Sci Med Sci2021
33275998Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence.Pharmacol Ther2021
32997601Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span.Annu Rev Pharmacol Toxicol2021
32285290Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues.Geroscience2020
37113577Development of an IGF1R longevity variant mouse line using CRISPR/Cas9 genome editing.Trends Biomed Res2020
31981461Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice.Aging Cell2020
31818691Urinary Extracellular Vesicles Carrying Klotho Improve the Recovery of Renal Function in an Acute Tubular Injury Model.Mol Ther2020
33378272ARDD 2020: from aging mechanisms to interventions.Aging (Albany NY)2020
32719537Genetics of extreme human longevity to guide drug discovery for healthy ageing.Nat Metab2020
32710480Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson-Gilford Progeria Syndrome.Aging Cell2020
32527988Influences of circulatory factors on intervertebral disc aging phenotype.Aging (Albany NY)2020
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Collaborators

Paul D Robbins
University of Minnesota
Co-authored papers 93
Yinsheng Wang
Co-authored papers 13
Sundeep Khosla
Co-authored papers 11
Aiping Lu
Co-authored papers 10
Nir Barzilai
Co-authored papers 10
Nikhil Bhagwat
Howard Hughes Medical Institute, University of California at Davis
Co-authored papers 6
Elizabeth J Atkinson
Mayo Clinic
Co-authored papers 6
Simon C Watkins
Center for Molecular Imaging, University of Pittsburgh School of Medicine
Co-authored papers 5
Ana Maria Cuervo
Albert Einstein College of Medicine
Co-authored papers 3
Gary Siuzdak
Scripps Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute
Co-authored papers 3
Stephen B Kritchevsky
Co-authored papers 3
Zhengdong D Zhang
Co-authored papers 3
Vera Gorbunova
University of Rochester
Co-authored papers 3
Alan D D'Andrea
Dana-Farber Cancer Institute
Co-authored papers 3
Vadim N Gladyshev
Brigham and Women's Hospital
Co-authored papers 2
Lin Wang
Co-authored papers 2
Tao Huan
University of British Columbia
Co-authored papers 2
Mohammad Fallahi
Co-authored papers 2
Erica M Forsberg
Viral Information Institute, San Diego State University
Co-authored papers 2
Bennett Van Houten
UPMC-Hillman Cancer Center, University of Pittsburgh
Co-authored papers 2
Aries Aisporna
Scripps Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute
Co-authored papers 2
Kathleen M Darcy
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.
Co-authored papers 2
Theodore M Kamenecka
Co-authored papers 2
Luke L Lairson
The Scripps Research Institute
Co-authored papers 2
Michael W W Adams
University of Georgia
Co-authored papers 2
Gil Atzmon
Co-authored papers 2
Luigi Ferrucci
National Institute on Aging, National Institutes of Health
Co-authored papers 2
Hilary P Benton
Scripps Center for Metabolomics and Mass Spectrometry, The Scripps Research Institute
Co-authored papers 2
Matthew W Fields
Center for Biofilm Engineering (CBE), Montana State University
Co-authored papers 2
Nathan A Yates
University of Pittsburgh School of Medicine
Co-authored papers 2
Release 1.2