Author details

Full Name

Belinda Giardine

Affiliation

ORCID

Career Start Year

2001

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37066352	Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.	bioRxiv	2024
36868189	Gene silencing dynamics are modulated by transiently active regulatory elements.		2023
38014261	Genome folding principles revealed in condensin-depleted mitotic chromosomes.		2023
36893455	Molecular basis of polycomb group protein-mediated fetal hemoglobin repression.		2023
36941541	Snapshot: a package for clustering and visualizing epigenetic history during cell differentiation.		2023
35618846	Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells.	Nature Genetics	2022
36371401	CLIMB: High-dimensional association detection in large scale genomic data.	Nature Communications	2022
36369346	CTCF blocks antisense transcription initiation at divergent promoters.	Nature Structural and Molecular Biology	2022
35650318	Publisher Correction: Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells.	Nature Genetics	2022
35941187	HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription.	Nature Genetics	2022
34453048	CTCF and transcription influence chromatin structure re-configuration after mitosis.	Nature Communications	2021
33681991	S3V2-IDEAS: a package for normalizing, denoising and integrating epigenomic datasets across different cell types.		2021
33626344	Distinct properties and functions of CTCF revealed by a rapidly inducible degron system.	Cell Rep	2021
33301730	ZNF410Â Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.	Molecular Cell	2021
33125055	Clinically relevant updates of the HbVar database of human hemoglobin variants and thalassemia mutations.	Nucleic Acids Research	2021
32956454	HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation.	Blood advances	2020
32268371	Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts.	Blood	2020
32299090	The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression.	Blood	2020
31769130	Systematic integration of GATA transcription factors and epigenomes via IDEAS paints the regulatory landscape of hematopoietic cells.	IUBMB Life	2020
32086521	S3norm: simultaneous normalization of sequencing depth and signal-to-noise ratio in epigenomic data.	Nucleic Acids Research	2020
32868908	Alteration of genome folding via contact domain boundary insertion.	Nature Genetics	2020
31126914	The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells.	Blood Adv	2019
31776509	Chromatin structure dynamics during the mitosis-to-G1 phase transition.	Nature	2019
30554946	Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation.	Molecular Cell	2019
30970245	Interrogating Histone Acetylation and BRD4 as Mitotic Bookmarks of Transcription.	Cell Rep	2019
29807547	Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points.	Epigenetics and Chromatin	2018
30026227	Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells.	Science	2018
29472540	Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility.	Nat Commun	2018
28388437	The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries.	Molecular Cell	2017
28916711	Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.	Genes Dev	2017
27340175	A hyperactive transcriptional state marks genome reactivation at the mitosis-G1 transition.	Genes and Development	2016
25729644	Dynamics of GATA1 binding and expression response in a GATA1-induced erythroid differentiation system.	Genomics Data	2015
25373146	Genome accessibility is widely preserved and locally modulated during mitosis.	Genome Res	2015
25696920	Functions of BET proteins in erythroid gene expression.	Blood	2015
24137000	Updates of the HbVar database of human hemoglobin variants and thalassemia mutations.	Nucleic Acids Research	2014
25409826	Principles of regulatory information conservation between mouse and human.	Nature	2014
23221638	Integrative annotation of chromatin elements from ENCODE data.	Nucleic Acids Res	2013
24377391	Galaxy tools to study genome diversity.	Gigascience	2013
23155063	The UCSC Genome Browser database: extensions and updates 2013.	Nucleic Acids Res	2013
22086951	The UCSC Genome Browser database: extensions and updates 2011.	Nucleic Acids Res	2012
22948727	Some phenotype association tools in Galaxy: looking for disease SNPs in a full genome.	Curr Protoc Bioinformatics	2012
21795386	Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration.	Genome Res	2011
21445068	The value of data.	Nat Genet	2011
21423179	Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach.	Nat Genet	2011
20959295	The UCSC Genome Browser database: update 2011.	Nucleic Acids Res	2011
19906737	The UCSC Genome Browser database: update 2010.	Nucleic Acids Res	2010
20164927	Complete Khoisan and Bantu genomes from southern Africa.	Nature	2010
18996895	The UCSC Genome Browser Database: update 2009.	Nucleic Acids Res	2009
19887574	Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression.	Genome Research	2009
18086701	The UCSC Genome Browser Database: 2008 update.	Nucleic Acids Res	2008