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Author Details

Ian Martin
Jungers Center for Neurosciences, Oregon Health and Science University
2003
37
21
PMIDPaper TitleJournal TitlePublished Year
36278358Unraveling Parkinson's Disease Neurodegeneration: Does Aging Hold the Clues?J Parkinsons Dis2022
33984508Dopamine neuron-specific LRRK2 G2019S effects on gene expression revealed by translatome profiling.Neurobiol Dis2021
34759048Dysregulated mRNA Translation in the G2019S LRRK2 and LRRK2 Knock-Out Mouse Brains.eNeuro2021
32605938Dietary Amino Acids Impact LRRK2-Induced Neurodegeneration in Parkinson's Disease Models.J Neurosci2020
29907646Genetic Modifiers of Neurodegeneration in a <i>Drosophila</i> Model of Parkinson's Disease.Genetics2018
28148845Resveratrol for Alzheimer's disease?Sci Transl Med2017
26899799LRRK2 pathobiology in Parkinson's disease - virtual inclusion.J Neurochem2016
27974660Alzheimer's medicine: β-Amyloid takes a siP.Sci Transl Med2016
27125634Parkinson disease: Insect screens for PD therapies - keep the flies in.Nat Rev Neurol2016
26889638Decoding Parkinson's Disease Pathogenesis: The Role of Deregulated mRNA Translation.J Parkinsons Dis2016
26808467LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity.J Chem Neuroanat2016
25342716A novel cholinergic action of alcohol and the development of tolerance to that effect in Caenorhabditis elegans.Genetics2015
24725412Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.Cell2014
25483009Abberant protein synthesis in G2019S LRRK2 Drosophila Parkinson disease-related phenotypes.Fly (Austin)2014
25251388LRRK2 pathobiology in Parkinson's disease.J Neurochem2014
25091824Paraquat exposure and Sod2 knockdown have dissimilar impacts on the Drosophila melanogaster carbonylated protein proteome.Proteomics2014
22239914Chloride intracellular channels modulate acute ethanol behaviors in Drosophila, Caenorhabditis elegans and mice.Genes Brain Behav2012
21639795Recent advances in the genetics of Parkinson's disease.Annu Rev Genomics Hum Genet2011
21615750The New York Stem Cell Foundation: Fifth Annual Translational Stem Cell Research Conference.Ann N Y Acad Sci2011
20696313The impact of genetic research on our understanding of Parkinson's disease.Prog Brain Res2010
19148770Multiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutants.Biogerontology2009
19481596A forward genetic screen in Drosophila implicates insulin signaling in age-related locomotor impairment.Exp Gerontol2009
19545620Sod2 knockdown in the musculature has whole-organism consequences in Drosophila.Free Radic Biol Med2009
19540235Manipulation of Sod1 expression ubiquitously, but not in the nervous system or muscle, impacts age-related parameters in Drosophila.FEBS Lett2009
18515028Genetic and environmental factors impact age-related impairment of negative geotaxis in Drosophila by altering age-dependent climbing speed.Exp Gerontol2008
17874997Dietary restriction alters demographic but not behavioral aging in Drosophila.Aging Cell2007
18078670Reduced mitochondrial SOD displays mortality characteristics reminiscent of natural aging.Mech Ageing Dev2007
16527333Oxidative damage and age-related functional declines.Mech Ageing Dev2006
16891076Distinct genetic influences on locomotor senescence in Drosophila revealed by a series of metrical analyses.Exp Gerontol2006
16024299Functional senescence in Drosophila melanogaster.Ageing Res Rev2005
15924573A proposed set of descriptors for functional senescence data.Aging Cell2005
15919590Rapid iterative negative geotaxis (RING): a new method for assessing age-related locomotor decline in Drosophila.Exp Gerontol2005
15039448Glutathione propagates oxidative stress triggered by myeloperoxidase in HL-60 cells. Evidence for glutathionyl radical-induced peroxidation of phospholipids and cytotoxicity.J Biol Chem2004
15281811Nitroxides scavenge myeloperoxidase-catalyzed thiyl radicals in model systems and in cells.J Am Chem Soc2004
15312159Arachidonic acid-induced carbon-centered radicals and phospholipid peroxidation in cyclo-oxygenase-2-transfected PC12 cells.J Neurochem2004
14967442Ascorbate as a "redox sensor" and protector against irradiation-induced oxidative stress in 32D CL 3 hematopoietic cells and subclones overexpressing human manganese superoxide dismutase.Int J Radiat Oncol Biol Phys2004
12595076Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells.Biochim Biophys Acta2003
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Collaborators

Institute for Cell Engineering, Johns Hopkins University School of Medicine
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Johns Hopkins University School of Medicine
Co-authored papers 8
Institute for Cell Engineering, Johns Hopkins University School of Medicine
Co-authored papers 5
Center for Free Radical and Antioxidant Health, University of Pittsburgh
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Jungers Center for Neurosciences, Oregon Health and Science University
Co-authored papers 1
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Virginia Commonwealth University
Co-authored papers 1
Penn State College of Medicine
Co-authored papers 1
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
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Center for Neuroscience, University of Pittsburgh
Co-authored papers 1
Mayo Clinic Jacksonville
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1