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Author Details

Brandon W Higgs
Translational and Clinical Data Sciences
2006
93
39
PMIDPaper TitleJournal TitlePublished Year
37572794Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes.J Hepatol2023
37572794Biliary atresia is associated with polygenic susceptibility in ciliogenesis and planar polarity effector genes.J Hepatol2023
34645581The Combiome Hypothesis: Selecting Optimal Treatment for Cancer Patients.Clin Lung Cancer2022
35492246A network-based approach to identify expression modules underlying rejection in pediatric liver transplantation.Cell Rep Med2022
34645581The Combiome Hypothesis: Selecting Optimal Treatment for Cancer Patients.Clin Lung Cancer2022
35492246A network-based approach to identify expression modules underlying rejection in pediatric liver transplantation.Cell Rep Med2022
33355200A Blood-based Assay for Assessment of Tumor Mutational Burden in First-line Metastatic NSCLC Treatment: Results from the MYSTIC Study.Clin Cancer Res2021
33972936Impaired T-cell and antibody immunity after COVID-19 infection in chronically immunosuppressed transplant recipients.bioRxiv2021
33257508A New Pipeline to Predict and Confirm Tumor Neoantigens Predict Better Response to Immune Checkpoint Blockade.Mol Cancer Res2021
33355200A Blood-based Assay for Assessment of Tumor Mutational Burden in First-line Metastatic NSCLC Treatment: Results from the MYSTIC Study.Clin Cancer Res2021
34845204High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control.Nat Commun2021
34845204High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control.Nat Commun2021
33972936Impaired T-cell and antibody immunity after COVID-19 infection in chronically immunosuppressed transplant recipients.bioRxiv2021
33257508A New Pipeline to Predict and Confirm Tumor Neoantigens Predict Better Response to Immune Checkpoint Blockade.Mol Cancer Res2021
32461104Tumor mutational burden and immune infiltration as independent predictors of response to neoadjuvant immune checkpoint inhibition in early TNBC in GeparNuevo.Ann Oncol2020
31657119CD154-expressing CMV-specific T cells associate with freedom from DNAemia and may be protective in seronegative recipients after liver or intestine transplantation.Pediatr Transplant2020
32461104Tumor mutational burden and immune infiltration as independent predictors of response to neoadjuvant immune checkpoint inhibition in early TNBC in GeparNuevo.Ann Oncol2020
32271377Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non-Small Cell Lung Cancer: The MYSTIC Phase 3 Randomized Clinical Trial.JAMA Oncol2020
33315971Selective amplification of hypermethylated DNA from diverse tumor types via MSRE-PCR.Oncotarget2020
33192543Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality.Front Physiol2020
31657119CD154-expressing CMV-specific T cells associate with freedom from DNAemia and may be protective in seronegative recipients after liver or intestine transplantation.Pediatr Transplant2020
33315971Selective amplification of hypermethylated DNA from diverse tumor types via MSRE-PCR.Oncotarget2020
33192543Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality.Front Physiol2020
32271377Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non-Small Cell Lung Cancer: The MYSTIC Phase 3 Randomized Clinical Trial.JAMA Oncol2020
30352801Improved Therapeutic Window in <i>BRCA</i>-mutant Tumors with Antibody-linked Pyrrolobenzodiazepine Dimers with and without PARP Inhibition.Mol Cancer Ther2019
30352801Improved Therapeutic Window in <i>BRCA</i>-mutant Tumors with Antibody-linked Pyrrolobenzodiazepine Dimers with and without PARP Inhibition.Mol Cancer Ther2019
31060602Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy.J Immunother Cancer2019
30778251The transcription factor c-Myb regulates CD8<sup>+</sup> T cell stemness and antitumor immunity.Nat Immunol2019
31327642Prognostic Significance of Liver Metastasis in Durvalumab-Treated Lung Cancer Patients.Clin Lung Cancer2019
31327642Prognostic Significance of Liver Metastasis in Durvalumab-Treated Lung Cancer Patients.Clin Lung Cancer2019
30778251The transcription factor c-Myb regulates CD8<sup>+</sup> T cell stemness and antitumor immunity.Nat Immunol2019
31060602Automated image analysis of NSCLC biopsies to predict response to anti-PD-L1 therapy.J Immunother Cancer2019
29069507Blockade of GM-CSF pathway induced sustained suppression of myeloid and T cell activities in rheumatoid arthritis.Rheumatology (Oxford)2018
29956883Baseline Plasma Cell Gene Signature Predicts Improvement in Systemic Sclerosis Skin Scores Following Treatment With Inebilizumab (MEDI-551) and Correlates With Disease Activity in Systemic Lupus Erythematosus and Chronic Obstructive Pulmonary Disease.Arthritis Rheumatol2018
30093454Early Reduction in ctDNA Predicts Survival in Patients with Lung and Bladder Cancer Treated with Durvalumab.Clin Cancer Res2018
29716923Interferon Gamma Messenger RNA Signature in Tumor Biopsies Predicts Outcomes in Patients with Non-Small Cell Lung Carcinoma or Urothelial Cancer Treated with Durvalumab.Clin Cancer Res2018
29243222Population Modeling of Tumor Kinetics and Overall Survival to Identify Prognostic and Predictive Biomarkers of Efficacy for Durvalumab in Patients With Urothelial Carcinoma.Clin Pharmacol Ther2018
29069507Blockade of GM-CSF pathway induced sustained suppression of myeloid and T cell activities in rheumatoid arthritis.Rheumatology (Oxford)2018
30093454Early Reduction in ctDNA Predicts Survival in Patients with Lung and Bladder Cancer Treated with Durvalumab.Clin Cancer Res2018
29956883Baseline Plasma Cell Gene Signature Predicts Improvement in Systemic Sclerosis Skin Scores Following Treatment With Inebilizumab (MEDI-551) and Correlates With Disease Activity in Systemic Lupus Erythematosus and Chronic Obstructive Pulmonary Disease.Arthritis Rheumatol2018
29716923Interferon Gamma Messenger RNA Signature in Tumor Biopsies Predicts Outcomes in Patients with Non-Small Cell Lung Carcinoma or Urothelial Cancer Treated with Durvalumab.Clin Cancer Res2018
29243222Population Modeling of Tumor Kinetics and Overall Survival to Identify Prognostic and Predictive Biomarkers of Efficacy for Durvalumab in Patients With Urothelial Carcinoma.Clin Pharmacol Ther2018
26950712Predicting Cellular Rejection With a Cell-Based Assay: Preclinical Evaluation in Children.Transplantation2017
28833989Synergistic immunosuppression and unintended consequences.Pediatr Transplant2017
29242501High-throughput RNA sequencing reveals distinct gene signatures in active IgG4-related disease.Sci Rep2017
26950712Predicting Cellular Rejection With a Cell-Based Assay: Preclinical Evaluation in Children.Transplantation2017
27923825Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery.Cancer Immunol Res2017
29242501High-throughput RNA sequencing reveals distinct gene signatures in active IgG4-related disease.Sci Rep2017
28833989Synergistic immunosuppression and unintended consequences.Pediatr Transplant2017
27923825Rational Selection of Syngeneic Preclinical Tumor Models for Immunotherapeutic Drug Discovery.Cancer Immunol Res2017
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MedImmune LLC
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Corbus Pharmaceuticals Holdings
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University of California
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BioKien LLC
Co-authored papers 5
Brigham Women's Hospital, Harvard Medical School
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Uniformed Services University
Co-authored papers 5
University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh
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