Author details

Full Name

Eleanor Wheeler

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37889320	Multi-omic prediction of incident type 2 diabetes.		2024
37096546	Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization.	Arthritis Rheumatol	2023
37923804	Identification of circulating proteins associated with general cognitive function among middle-aged and older adults.	Commun Biol	2023
37550624	Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases.	Clin Proteomics	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
37034613	Unraveling Neuro-Proteogenomic Landscape and Therapeutic Implications for Human Behaviors and Psychiatric Disorders.	Res Sq	2023
37400433	Causal associations between cardiorespiratory fitness and type 2 diabetes.		2023
36824751	Genetic mechanisms of 184 neuro-related proteins in human plasma.	medRxiv	2023
36823471	Proteogenomic links to human metabolic diseases.		2023
36693378	Loci for insulin processing and secretion provide insight into type 2 diabetes risk.	Am J Hum Genet	2023
36693275	Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults.		2023
36935425	Author Correction: Proteogenomic links to human metabolic diseases.		2023
37429843	Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure.	Nat Commun	2023
34875679	Identification of Rare Loss-of-Function Genetic Variation Regulating Body Fat Distribution.	Journal of Clinical Endocrinology and Metabolism	2022
35970849	ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19.	Nat Commun	2022
36357677	Proteomic signatures for identification of impaired glucose tolerance.	Nature Medicine	2022
35387486	Genetic Landscape of the ACE2 Coronavirus Receptor.	Circulation	2022
35754192	Development and validation of a metabolite score for red meat intake: an observational cohort study and randomized controlled dietary intervention.	American Journal of Clinical Nutrition	2022
36530175	Damaging missense variants in implicate a role for IGF-1 resistance in the etiology of type 2 diabetes.		2022
34648354	Mapping the proteo-genomic convergence of human diseases.	Science	2021
34234147	GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health.	Nat Commun	2021
33851187	Mendelian randomisation identifies alternative splicing of the FAS death receptor as a mediator of severe COVID-19.	medRxiv	2021
33531486	Author Correction: Genetic architecture of host proteins involved in SARS-CoV-2 infection.	Nat Commun	2021
33414548	A cross-platform approach identifies genetic regulators of human metabolism and health.	Nat Genet	2021
34857772	Mapping the serum proteome to neurological diseases using whole genome sequencing.	Nat Commun	2021
34426508	Genetically Predicted Glucose-Dependent Insulinotropic Polypeptide (GIP) Levels and Cardiovascular Disease Risk Are Driven by Distinct Causal Variants in the <i>GIPR</i> Region.	Diabetes	2021
34819519	Synergistic insights into human health from aptamer- and antibody-based proteomic profiling.	Nature Communications	2021
33328453	Genetic architecture of host proteins involved in SARS-CoV-2 infection.	Nat Commun	2020
32492392	Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription.	Cell Metab	2020
32150548	The influence of rare variants in circulating metabolic biomarkers.	PLoS Genet	2020
33045005	Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.	PLoS Genet	2020
33096487	Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes.	eBioMedicine	2020
33188205	Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study.	Sci Data	2020
32637948	Genetic architecture of host proteins interacting with SARS-CoV-2.	bioRxiv	2020
31049640	Genome-wide association study of type 2 diabetes in Africa.	Diabetologia	2019
31675503	Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.	Cell	2019
31002796	Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.	Cell	2019
29522974	Genetics of HbA1c: a case study in clinical translation.	Current Opinion in Genetics and Development	2018
29876888	Key Concepts in Genetic Epidemiology.	Methods in Molecular Biology	2018
28138151	Corrigendum: Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.	Nat Genet	2017
28898252	Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.	PLoS Med	2017
28977447	Genetic aetiology of glycaemic traits: approaches and insights.	Human Molecular Genetics	2017
28663568	Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity.	Sci Rep	2017
27841877	Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.	Nat Genet	2017
27863252	The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.	Cell	2016
26411566	A Bayesian Approach to the Overlap Analysis of Epidemiologically Linked Traits.	Genet Epidemiol	2015
25105364	Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance.	Journal of Clinical Investigation	2014
24845081	Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study.	PLoS Med	2014
23563609	Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity.	Nat Genet	2013
23778139	Rare variants in single-minded 1 (SIM1) are associated with severe obesity.	J Clin Invest	2013