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Author Details

Yolanda Sanchez
Collegeville
1985
108
44
PMIDPaper TitleJournal TitlePublished Year
36724365NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease.Am J Respir Crit Care Med2023
36430366Fission Yeast Rho1p-GEFs: From Polarity and Cell Wall Synthesis to Genome Stability.Int J Mol Sci2022
34575767The Role of the Cell Integrity Pathway in Septum Assembly in Yeast.J Fungi (Basel)2021
34705450Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction.J Med Chem2021
34666001Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast.Dev Cell2021
32267199Tumor microtubes connect pancreatic cancer cells in an Arp2/3 complex-dependent manner.Mol Biol Cell2020
33103994A novel checkpoint pathway controls actomyosin ring constriction trigger in fission yeast.Elife2020
30626555Discovery of a crystalline sulforaphane analog with good solid-state stability and engagement of the Nrf2 pathway in vitro and in vivo.Bioorg Med Chem2019
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
31505685Scientific Business Abstracts of the 113th Annual Meeting of the Association of Physicians of Great Britain and Ireland.QJM2019
30973731Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein Interaction.J Med Chem2019
31002701Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease.PLoS One2019
29533925Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation.J Clin Invest2018
29617658Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.Cell Rep2018
29547002Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease Is Enhanced by Nrf2 Agonists.Am J Respir Crit Care Med2018
28790194Characterization of the Potent, Selective Nrf2 Activator, 3-(Pyridin-3-Ylsulfonyl)-5-(Trifluoromethyl)-2<i>H</i>-Chromen-2-One, in Cellular and In Vivo Models of Pulmonary Oxidative Stress.J Pharmacol Exp Ther2017
28334931Rgf1p (Rho1p GEF) is required for double-strand break repair in fission yeast.Nucleic Acids Res2017
28166733A machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastoma.BMC Genomics2017
29662612Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells.Oncotarget2017
29095909Correction: Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells and monocytes.PLoS One2017
28886135Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells and monocytes.PLoS One2017
26196323Expanding the p53 regulatory network: LncRNAs take up the challenge.Biochim Biophys Acta2016
26934555Genomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sites.Oncotarget2016
27031670Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery.J Med Chem2016
25780921Identification and characterization of PERK activators by phenotypic screening and their effects on NRF2 activation.PLoS One2015
26574138Stephen Elledge and the DNA damage response.DNA Repair (Amst)2015
25697088Neuro-otologic manifestations of tuberculosis. "The great imitator".Am J Otolaryngol2015
24478458The checkpoint-dependent nuclear accumulation of Rho1p exchange factor Rgf1p is important for tolerance to chronic replication stress.Mol Biol Cell2014
25524025Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature.Nat Commun2014
24947517The putative exchange factor Gef3p interacts with Rho3p GTPase and the septin ring during cytokinesis in fission yeast.J Biol Chem2014
24563904Analytical approaches for quantification of a Nrf2 pathway activator: overcoming bioanalytical challenges to support a toxicity study.Analyst2014
23391415Long non-coding RNAs: challenges for diagnosis and therapies.Nucleic Acid Ther2013
24070194Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2.Genome Biol2013
23825576Biochemical characterization of Paracoccidioides brasiliensis α-1,3-glucanase Agn1p, and its functionality by heterologous Expression in Schizosaccharomyces pombe.PLoS One2013
23907979The fission yeast cell wall stress sensor-like proteins Mtl2 and Wsc1 act by turning on the GTPase Rho1p but act independently of the cell wall integrity pathway.Microbiologyopen2013
21697395Discovery of a small molecule targeting IRA2 deletion in budding yeast and neurofibromin loss in malignant peripheral nerve sheath tumor cells.Mol Cancer Ther2011
22033190Xenografts in zebrafish embryos as a rapid functional assay for breast cancer stem-like cell identification.Cell Cycle2011
21779180Proteins in the nutrient-sensing and DNA damage checkpoint pathways cooperate to restrain mitotic progression following DNA damage.PLoS Genet2011
20078209Compatibility and stability of ternary admixtures of tramadol, haloperidol, and hyoscine N-butyl bromide: retrospective clinical evaluation.J Palliat Med2010
20716966Deregulated Ras signaling compromises DNA damage checkpoint recovery in S. cerevisiae.Cell Cycle2010
20641019Cell separation and the maintenance of cell integrity during cytokinesis in yeast: the assembly of a septum.Yeast2010
20605902Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.J Pharmacol Exp Ther2010
19000667Serum soluble transferrin receptor concentrations are increased in central obesity. Results from a screening programme for hereditary hemochromatosis in men with hyperferritinemia.Clin Chim Acta2009
19720055Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.Chem Biol Interact2009
19778378U2OS cells lacking Chk1 undergo aberrant mitosis and fail to activate the spindle checkpoint.J Cell Mol Med2009
19411848Conserved ATRMec1 phosphorylation-independent activation of Chk1 by single amino acid substitution in the GD domain.Cell Cycle2009
19189958Fission yeast rgf2p is a rho1p guanine nucleotide exchange factor required for spore wall maturation and for the maintenance of cell integrity in the absence of rgf1p.Genetics2009
18984588ATRMec1 phosphorylation-independent activation of Chk1 in vivo.J Biol Chem2009
19038232Regulation of genistein-induced differentiation in human acute myeloid leukaemia cells (HL60, NB4) Protein kinase modulation and reactive oxygen species generation.Biochem Pharmacol2009
19037094The Rho1p exchange factor Rgf1p signals upstream from the Pmk1 mitogen-activated protein kinase pathway in fission yeast.Mol Biol Cell2009
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Collaborators

Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 6
Oregon Health & Science University
Co-authored papers 5
Whitehead Institute for Biomedical Research
Co-authored papers 4
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 4
Co-authored papers 4
Geisel School of Medicine, Dartmouth College
Co-authored papers 3
Center for Genomic Medicine, Massachusetts General Hospital
Co-authored papers 3
Instituto Goncalo Moniz, Yale School of Public Health
Co-authored papers 3
Broad Institute of MIT and Harvard
Co-authored papers 3
Dartmouth-Hitchcock Medical Center
Co-authored papers 2
The University of Texas M. D. Anderson Cancer Center
Co-authored papers 2
Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth
Co-authored papers 2
Vall d'Hebron Institute of Oncology (VHIO)
Co-authored papers 2
Center for Applied Medical Research (CIMA)
Co-authored papers 2
Dartmouth-Hitchcock Medical Center
Co-authored papers 2
Tianjin University of Traditional Chinese Medicine
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Dartmouth Health and the Dartmouth Cancer Center, USA Geisel School of Medicine
Co-authored papers 1
The University of Texas Health Science Center at San Antonio
Co-authored papers 1
Post Graduate Institute of Medical Education and Research
Co-authored papers 1
Sun Yat-sen University Cancer Center
Co-authored papers 1
University of Lausanne (UNIL)
Co-authored papers 1
Cancer Center, Texas Tech University Health Sciences Center School of Medicine
Co-authored papers 1
Co-authored papers 1
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 1
Co-authored papers 1
Epigenetics Institute, University of Pennsylvania
Co-authored papers 1
Geisel School of Medicine, Dartmouth College
Co-authored papers 1
University Hospital Regensburg
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1