Author details

Full Name

Colleen Fearns

Affiliation

ORCID

Career Start Year

1992

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
27165517	Current and future treatment of amyloid diseases.	Journal of Internal Medicine	2016
26338154	Targeting protein aggregation for the treatment of degenerative diseases.	Nat Rev Drug Discov	2015
22244854	The transthyretin amyloidoses: from delineating the molecular mechanism of aggregation linked to pathology to a regulatory-agency-approved drug.	Journal of Molecular Biology	2012
22273578	Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment.	Molecular Therapy	2012
20832753	Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein.	Cancer Cell	2010
19276368	CDC25B mediates rapamycin-induced oncogenic responses in cancer cells.	Cancer Res	2009
19406746	Kinome siRNA screen identifies SMG-1 as a negative regulator of hypoxia-inducible factor-1alpha in hypoxia.	Journal of Biological Chemistry	2009
19351860	Combined integrin phosphoproteomic analyses and small interfering RNA--based functional screening identify key regulators for cancer cell adhesion and migration.	Cancer Res	2009
19426145	Nuclear factor kappaB (NF-kappaB) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist.	Biochemical Journal	2009
17982484	Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling.	Oncogene	2008
17403772	MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.	Journal of Leukocyte Biology	2007
16327803	A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy.	Nature Medicine	2006
16968706	Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding.	Journal of Biological Chemistry	2006
16893899	N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.	J Biol Chem	2006
16479018	Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.	J Lipid Res	2006
16204048	Tid1 negatively regulates the migratory potential of cancer cells by inhibiting the production of interleukin-8.	Cancer Research	2005
15879105	Tid1 is required for T cell transition from double-negative 3 to double-positive stages.	Journal of Immunology	2005
16140937	Big mitogen-activated protein kinase 1/extracellular signal-regulated kinase 5 signaling pathway is essential for tumor-associated angiogenesis.	Cancer Research	2005
14993262	Tid1, a cochaperone of the heat shock 70 protein and the mammalian counterpart of the Drosophila tumor suppressor l(2)tid, is critical for early embryonic development and cell survival.	Molecular and Cellular Biology	2004
15520177	Tid1, the human homologue of a Drosophila tumor suppressor, reduces the malignant activity of ErbB-2 in carcinoma cells.	Cancer Research	2004
14633627	MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury.	American Journal of Pathology	2003
11870620	Expression and role of CD14 in mice sensitized to lipopolysaccharide by Propionibacterium acnes.	European Journal of Immunology	2002
10848581	Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest.	Molecular and Cellular Biology	2000
10811012	Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli.	Journal of Leukocyte Biology	2000
11106558	Inhibition of the tissue factor-thrombin pathway limits infarct size after myocardial ischemia-reperfusion injury by reducing inflammation.	American Journal of Pathology	2000
10393961	Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation.	Proceedings of the National Academy of Sciences of the United States of America	1999
10225918	Lipopolysaccharide induction of tissue factor expression in rabbits.	Infection and Immunity	1999
10202018	The origin and function of soluble CD14 in experimental bacterial meningitis.	J Immunol	1999
9763564	Tissue distribution and regulation of murine von Willebrand factor gene expression in vivo.	Blood	1998
9525321	Effect of recombinant interleukin-1beta on murine CD14 gene expression in vivo.	Shock	1998
9353071	Role of tumor necrosis factor alpha in induction of murine CD14 gene expression by lipopolysaccharide.	Infection and Immunity	1997
9033272	Induction of plasminogen activator inhibitor 1 gene expression in murine liver by lipopolysaccharide. Cellular localization and role of endogenous tumor necrosis factor-alpha.	American Journal of Pathology	1997
7532683	Murine CD14 gene expression in vivo: extramyeloid synthesis and regulation by lipopolysaccharide.	Journal of Experimental Medicine	1995
1537627	The desmoplastic response: induction of collagen synthesis by melanoma cells in vitro.	International Journal of Cancer	1992
1562456	Unusual growth characteristics of human melanoma xenografts in the nude mouse: a model for desmoplasia, dormancy and progression.	British Journal of Cancer	1992