Author details

Full Name

Pauline Chabosseau

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36980244	ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition.		2023
38076935	Differential CpG methylation at in the early establishment of beta cell heterogeneity.		2023
35294578	Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.	Diabetologia	2022
35476777	Glucose-Dependent miR-125b Is a Negative Regulator of Î²-Cell Function.		2022
35472764	Mitofusins Mfn1 and Mfn2 Are Required to Preserve Glucose- but Not Incretin-Stimulated Î²-Cell Connectivity and Insulin Secretion.		2022
34545099	Author Correction: Intravital imaging of islet Ca dynamics reveals enhanced Î² cell connectivity after bariatric surgery in mice.	Nature Communications	2021
33492421	Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.	Diabetologia	2021
33960419	The Ca -binding protein sorcin stimulates transcriptional activity of the unfolded protein response mediator ATF6.	FEBS Letters	2021
33989778	Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated Î²-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.	Molecular Metabolism	2021
33498234	Importance of Both Imprinted Genes and Functional Heterogeneity in Pancreatic Beta Cells: Is There a Link?	International Journal of Molecular Sciences	2021
34453049	Intravital imaging of islet Ca dynamics reveals enhanced Î² cell connectivity after bariatric surgery in mice.	Nature Communications	2021
30718914	An essential role for the Zn transporter ZIP7 in B cell development.	Nature Immunology	2019
31676859	Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.	Nature Genetics	2019
29686402	Targeting GLP-1 receptor trafficking to improve agonist efficacy.	Nature Communications	2018
30310153	The Î±-cell in diabetes mellitus.	Nature Reviews Endocrinology	2018
29864031	Neuronatin regulates pancreatic Î² cell insulin content and secretion.	Journal of Clinical Investigation	2018
30038024	Mice harboring the human R138X loss-of-function mutation have increased insulin secretory capacity.	Proceedings of the National Academy of Sciences of the United States of America	2018
29431830	Sensors for measuring subcellular zinc pools.	Metallomics	2018
29284659	A Targeted RNAi Screen Identifies Endocytic Trafficking Factors That Control GLP-1 Receptor Signaling in Pancreatic Î²-Cells.		2018
28132686	Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice.	American Journal of Human Genetics	2017
28466490	Local and regional control of calcium dynamics in the pancreatic islet.	Diabetes Obes Metab	2017
28377501	The transcription factor <i>Pax6</i> is required for pancreatic Î² cell identity, glucose-regulated ATP synthesis, and Ca<sup>2+</sup> dynamics in adult mice.	J Biol Chem	2017
28334855	SLC30A9 mutation affecting intracellular zinc homeostasis causes a novel cerebro-renal syndrome.	Brain	2017
26584158	Molecular Genetic Regulation of Slc30a8/ZnT8 Reveals a Positive Association With Glucose Tolerance.	Mol Endocrinol	2016
27390586	Over-expression of Slc30a8/ZnT8 selectively in the mouse Î± cell impairs glucagon release and responses to hypoglycemia.	Nutrition and Metabolism	2016
27329800	Changes in the expression of the type 2 diabetes-associated gene VPS13C in the Î²-cell are associated with glucose intolerance in humans and mice.	Am J Physiol Endocrinol Metab	2016
26861785	Disallowance of Acot7 in Î²-Cells Is Required for Normal Glucose Tolerance and Insulin Secretion.		2016
27262257	Zinc and diabetes.	Archives of Biochemistry and Biophysics	2016
26365743	Intracellular zinc in insulin secretion and action: a determinant of diabetes risk?	Proc Nutr Soc	2016
26151333	eZinCh-2: A Versatile, Genetically Encoded FRET Sensor for Cytosolic and Intraorganelle Zn(2+) Imaging.	ACS Chemical Biology	2015
26258299	The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.	Nature	2015
25011072	Mitochondrial and ER-targeted eCALWY probes reveal high levels of free Zn2+.	ACS Chemical Biology	2014
25119717	Divergent effects of liraglutide, exendin-4, and sitagliptin on beta-cell mass and indicators of pancreatitis in a mouse model of hyperglycaemia.	PLoS ONE	2014
21712816	Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome.	Nature Communications	2011
20454621	Genetic interactions show the importance of rRNA modification machinery for the role of Rps15p during ribosome biogenesis in S. cerevisiae.	PLoS ONE	2010
20215422	The Bloom syndrome protein limits the lethality associated with RAD51 deficiency.	Molecular Cancer Research	2010