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Author Details

Kristine L Witt
National Institute of Environmental Health Sciences/National Institutes of Health
1989
107
35
PMIDPaper TitleJournal TitlePublished Year
36646809Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing.Nat Rev Drug Discov2023
37643677Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment.Mutat Res Rev Mutat Res2023
37770135Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats.Mutat Res Genet Toxicol Environ Mutagen2023
37214853Adopting Duplex Sequencingâ¿¢ Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats.bioRxiv2023
36646809Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing.Nat Rev Drug Discov2023
36880770Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate-based formulations for genotoxic activity using in vitro assays.Environ Mol Mutagen2023
37300447Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology.Mutagenesis2023
37491114Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency.Mutat Res Genet Toxicol Environ Mutagen2023
37097075Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT).Environ Mol Mutagen2023
37491114Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency.Mutat Res Genet Toxicol Environ Mutagen2023
37643677Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment.Mutat Res Rev Mutat Res2023
37770135Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats.Mutat Res Genet Toxicol Environ Mutagen2023
37214853Adopting Duplex Sequencingâ¿¢ Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats.bioRxiv2023
37300447Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology.Mutagenesis2023
37097075Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT).Environ Mol Mutagen2023
36880770Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate-based formulations for genotoxic activity using in vitro assays.Environ Mol Mutagen2023
36323641A cross-sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements.Environ Mol Mutagen2022
35435491Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation.Arch Toxicol2022
36323641A cross-sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements.Environ Mol Mutagen2022
35473450The common indoor air pollutant α-pinene is metabolised to a genotoxic metabolite α-pinene oxide.Xenobiotica2022
35473450The common indoor air pollutant α-pinene is metabolised to a genotoxic metabolite α-pinene oxide.Xenobiotica2022
35435491Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation.Arch Toxicol2022
33388407Oral deoxynivalenol toxicity in Harlan Sprague Dawley (Hsd:Sprague Dawley® SD®) rat dams and their offspring.Food Chem Toxicol2021
33856461Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells.Toxicol Sci2021
33777704Comparison of sulfolane effects in Sprague Dawley rats, B6C3F1/N mice, and Hartley guinea pigs after 28 days of exposure via oral gavage.Toxicol Rep2021
33727136The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells.Toxicol Lett2021
33388407Oral deoxynivalenol toxicity in Harlan Sprague Dawley (Hsd:Sprague Dawley® SD®) rat dams and their offspring.Food Chem Toxicol2021
33727136The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells.Toxicol Lett2021
33777704Comparison of sulfolane effects in Sprague Dawley rats, B6C3F1/N mice, and Hartley guinea pigs after 28 days of exposure via oral gavage.Toxicol Rep2021
33856461Mechanistic Evaluation of Black Cohosh Extract-Induced Genotoxicity in Human Cells.Toxicol Sci2021
31633839Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposure.Environ Mol Mutagen2020
31600846Mutation as a Toxicological Endpoint for Regulatory Decision-Making.Environ Mol Mutagen2020
32380031Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies.Toxicology2020
31633839Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposure.Environ Mol Mutagen2020
31875426Response to Letter to the Editor.Environ Mol Mutagen2020
32159784Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing.Toxicol Sci2020
32281969Use of Frozen Tissue in the Comet Assay for the Evaluation of DNA Damage.J Vis Exp2020
32798647Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines.Food Chem Toxicol2020
32845000Corrigendum to: "Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing".Toxicol Sci2020
31875426Response to Letter to the Editor.Environ Mol Mutagen2020
32798647Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines.Food Chem Toxicol2020
32845000Corrigendum to: "Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing".Toxicol Sci2020
32281969Use of Frozen Tissue in the Comet Assay for the Evaluation of DNA Damage.J Vis Exp2020
32380031Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies.Toxicology2020
32159784Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing.Toxicol Sci2020
31600846Mutation as a Toxicological Endpoint for Regulatory Decision-Making.Environ Mol Mutagen2020
30818834Identification of Compounds That Inhibit Estrogen-Related Receptor Alpha Signaling Using High-Throughput Screening Assays.Molecules2019
31569270Evidence for an Aneugenic Mechanism of Action for Micronucleus Induction by Black Cohosh Extract.Environ Mol Mutagen2019
30818834Identification of Compounds That Inhibit Estrogen-Related Receptor Alpha Signaling Using High-Throughput Screening Assays.Molecules2019
30744809A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.Mutat Res Genet Toxicol Environ Mutagen2019
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Collaborators

National Institute of Environmental Health Sciences
Co-authored papers 26
National Institute of Environmental Health Sciences
Co-authored papers 15
National Institute of Environmental Health Sciences
Co-authored papers 12
St. George's University Medical School
Co-authored papers 10
Harvard Medical School, Beth Israel Hospital
Co-authored papers 6
Carleton University
Co-authored papers 6
University of Ottawa
Co-authored papers 4
Co-authored papers 4
Center for Environmental Measurement and Modeling
Co-authored papers 3
University of California Los Angeles
Co-authored papers 2
University of California San Diego
Co-authored papers 2
University of Michigan ann arbor
Co-authored papers 2
New York University School of Medicine
Co-authored papers 2
Tufts University
Co-authored papers 2
Center for Computational Sciences
Co-authored papers 2
National Institute of Environmental Health Sciences
Co-authored papers 2
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of Oklahoma
Co-authored papers 2
Co-authored papers 2
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Washington University School of Medicine
Co-authored papers 1
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National Institute of Environmental Health Sciences, National Institutes of Health
Co-authored papers 1
University of Michigan ann arbor
Co-authored papers 1
McGill University
Co-authored papers 1
National Institute of Environmental Health Sciences
Co-authored papers 1
University of South Alabama
Co-authored papers 1
Co-authored papers 1