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Author Details

Bryan Lo
The Ottawa Hospital/University of Ottawa
1994
38
14
PMIDPaper TitleJournal TitlePublished Year
36136297Molecular Pathogenesis of Penile Squamous Cell Carcinoma: Current Understanding and Potential Treatment Implications.Arch Pathol Lab Med2023
37185415Consensus Recommendations to Optimize the Detection and Reporting of <i>NTRK</i> Gene Fusions by RNA-Based Next-Generation Sequencing.Curr Oncol2023
37100730A rare case of false negative ROS1 fusion in metastatic pulmonary adenocarcinoma: Case report and lessons learned.Clin Lung Cancer2023
36586421CANTRK: A Canadian Ring Study to Optimize Detection of NTRK Gene Fusions by Next-Generation RNA Sequencing.J Mol Diagn2023
35195689CAP-ACP Workload Model for Advanced Diagnostics in Precision Medicine.Am J Clin Pathol2022
35538551Neuroendocrine differentiation distinguishes basaloid variant of lung squamous cell carcinoma.Diagn Pathol2022
35892985Costs of Next-Generation Sequencing Assays in Non-Small Cell Lung Cancer: A Micro-Costing Study.Curr Oncol2022
33450821A Contemporary Report of Clinical Outcomes in Patients with Melanoma Brain Metastases.Curr Oncol2021
33811746Tumor genomic, transcriptomic, and immune profiling characterizes differential response to first-line platinum chemotherapy in high grade serous ovarian cancer.Cancer Med2021
33555379Personalized oncology and BRAF<sup>K601N</sup> melanoma: model development, drug discovery, and clinical correlation.J Cancer Res Clin Oncol2021
34766461The need for speed in advanced non-small cell lung cancer: A population kinetics assessment.Cancer Med2021
34590051A Pan-Canadian Validation Study for the Detection of <i>EGFR</i> T790M Mutation Using Circulating Tumor DNA From Peripheral Blood.JTO Clin Res Rep2021
34381713The Impact of Foundation Medicine Testing on Cancer Patients: A Single Academic Centre Experience.Front Oncol2021
34696852Systemic Therapy in Nonsmall Cell Lung Cancer and the Role of Biomarkers in Selection of Treatment.Thorac Surg Clin2021
34597339Multisite verification of the accuracy of a multi-gene next generation sequencing panel for detection of mutations and copy number alterations in solid tumours.PLoS One2021
34145744Homozygous WNT9B variants in two families with bilateral renal agenesis/hypoplasia/dysplasia.Am J Med Genet A2021
31597663Metformin Abrogates Age-Associated Ovarian Fibrosis.Clin Cancer Res2020
33059707Accuracy and reproducibility of somatic point mutation calling in clinical-type targeted sequencing data.BMC Med Genomics2020
31095693A dural-based spindle cell neoplasm characterized by a novel MN1-KMT2A fusion gene.Neuro Oncol2019
31896942Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study.Curr Oncol2019
31708655OCTANE (Ontario-wide Cancer Targeted Nucleic Acid Evaluation): a platform for intraprovincial, national, and international clinical data-sharing.Curr Oncol2019
31043833A Canadian guideline on the use of next-generation sequencing in oncology.Curr Oncol2019
28068672Genomic hallmarks of localized, non-indolent prostate cancer.Nature2017
28377483Vulvar Squamous Cell Carcinoma (VSCC) as Two Diseases: HPV Status Identifies Distinct Mutational Profiles Including Oncogenic Fibroblast Growth Factor Receptor 3.Clin Cancer Res2017
23712430MARCH1-mediated MHCII ubiquitination promotes dendritic cell selection of natural regulatory T cells.J Exp Med2013
23266956Lkb1 regulates organogenesis and early oncogenesis along AMPK-dependent and -independent pathways.J Cell Biol2012
21444686A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells.J Cell Biol2011
18448629Transmembrane IV of the high-affinity sodium-glucose cotransporter participates in sugar binding.Am J Physiol Cell Physiol2008
16123220Requirement of VPS33B, a member of the Sec1/Munc18 protein family, in megakaryocyte and platelet alpha-granule biogenesis.Blood2005
15052268Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome.Nat Genet2004
15592663Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search for the aetiology of a new autosomal recessive syndrome.Diabetologia2004
15500499Liver biopsy complicated by hemorrhage in a patient with ARC syndrome.Paediatr Anaesth2004
14984473The locus responsible for horizontal gaze palsy/progressive scoliosis and brainstem hypoplasia is refined to a 9-cM region on chromosome 11q23.Clin Genet2004
12900899Novel mutation in the gene encoding c-Abl-binding protein SH3BP2 causes cherubism.Am J Med Genet A2003
9792634Cysteine scanning mutagenesis of the segment between putative transmembrane helices IV and V of the high affinity Na+/Glucose cotransporter SGLT1. Evidence that this region participates in the Na+ and voltage dependence of the transporter.J Biol Chem1998
9422748Replacement of Ala-166 with cysteine in the high affinity rabbit sodium/glucose transporter alters transport kinetics and allows methanethiosulfonate ethylamine to inhibit transporter function.J Biol Chem1998
9576859Functional studies of the rabbit intestinal Na+/glucose carrier (SGLT1) expressed in COS-7 cells: evaluation of the mutant A166C indicates this region is important for Na+-activation of the carrier.Biochem J1998
7948786Characterization of cimetidine transport in LLCPK1 cells.J Am Soc Nephrol1994
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Collaborators

Genentech Inc.
Co-authored papers 3
Centre Hospitalier de l'Universite de Montreal
Co-authored papers 3
Institut du cancer de Montreal
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Ottawa Hospital Research Institute
Co-authored papers 2
Cancer Clinical Research Unit, Princess Margaret Cancer Centre
Co-authored papers 2
The University of Hong Kong
Co-authored papers 2
University Health Network, University of Toronto
Co-authored papers 2
The Ottawa Hospital/University of Ottawa
Co-authored papers 2
Princess Margaret Cancer Centre, University Ave
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
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Children's Hospital of Pittsburgh
Co-authored papers 2
The Ottawa Hospital Research Institute
Co-authored papers 2
The Hospital for Sick Children
Co-authored papers 2
Rutgers Robert Wood Johnson Medical School
Co-authored papers 1
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Centre de Recherche du CHU de Quebec-Universite Laval (axe Oncologie)
Co-authored papers 1
Ottawa Hospital Research Institute
Co-authored papers 1
Ontario Institute for Cancer Research
Co-authored papers 1
Princess Margaret Cancer Center, University Health Network, University of Toronto
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University of California los angeles
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Human Longevity Inc.
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University Health Network
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McMaster University
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Toronto General Hospital, University Health Network, University of Toronto
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Children's Hospital of Eastern Ontario
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National Cancer Centre
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Ontario Institute for Cancer Research
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Centre de Recherche du CHU de Quebec-Universite Laval (axe Oncologie)
Co-authored papers 1