Author details

Full Name

Shoshana D Brown

Affiliation

University of California san francisco

ORCID

Career Start Year

1999

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
32242662	Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.	Biochemistry	2020
32449511	A strategy for large-scale comparison of evolutionary- and reaction-based classifications of enzyme function.	Database (Oxford)	2020
30398656	InterPro in 2019: improving coverage, classification and access to protein sequence annotations.	Nucleic Acids Res	2019
31074977	Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.	Biochemistry	2019
30097089	Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain.	Methods Enzymol	2018
28054422	An approach to functionally relevant clustering of the protein universe: Active site profile-based clustering of protein structures and sequences.	Protein Sci	2017
28365730	Biocuration in the structure-function linkage database: the anatomy of a superfamily.	Database (Oxford)	2017
28605775	Biocuration in the structure-function linkage database: the anatomy of a superfamily.	Database (Oxford)	2017
27650333	Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha.	Plant Cell	2016
25513739	Covalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatases.	Biochemistry	2015
25855808	Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.	Nucleic Acids Res	2015
24271399	The Structure-Function Linkage Database.	Nucleic Acids Res	2014
25501940	Using the structure-function linkage database to characterize functional domains in enzymes.	Curr Protoc Bioinformatics	2014
25210038	New insights about enzyme evolution from large scale studies of sequence and structure relationships.	J Biol Chem	2014
24980702	Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks.	Elife	2014
23676670	Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function.	Nature	2013
24056934	Discovery of new enzymes and metabolic pathways by using structure and genome context.	Nature	2013
23959887	Consequences of domain insertion on sequence-structure divergence in a superfold.	Proc Natl Acad Sci U S A	2013
22069325	Inference of functional properties from large-scale analysis of enzyme superfamilies.	J Biol Chem	2012
22392983	Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.	Proc Natl Acad Sci U S A	2012
19219566	Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies.	J Struct Funct Genomics	2009
20011109	Annotation error in public databases: misannotation of molecular function in enzyme superfamilies.	PLoS Comput Biol	2009
19518059	Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily.	Biochemistry	2009
19220063	Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes.	Biochemistry	2009
18171028	At the periphery of the amidohydrolase superfamily: Bh0493 from Bacillus halodurans catalyzes the isomerization of D-galacturonate to D-tagaturonate.	Biochemistry	2008
17500569	Kinetics of the deprotonation of methylnitroacetate by amines: unusually high intrinsic rate constants for a nitroalkane.	J Org Chem	2007
17603539	Prediction and assignment of function for a divergent N-succinyl amino acid racemase.	Nat Chem Biol	2007
17567048	Structural diversity within the mononuclear and binuclear active sites of N-acetyl-D-glucosamine-6-phosphate deacetylase.	Biochemistry	2007
17407355	Spectroscopic and kinetic evidence for an accumulating intermediate in an SNV reaction with amine nucleophiles. Reaction of methyl beta-methylthio-alpha-nitrocinnamate with piperidine and morpholine.	J Org Chem	2007
16507141	A gold standard set of mechanistically diverse enzyme superfamilies.	Genome Biol	2006
18428763	Using the Structure-function Linkage Database to characterize functional domains in enzymes.	Curr Protoc Bioinformatics	2006
16776504	Hydrolysis of alpha-alkyl-alpha-(methylthio)methylene Meldrum's acids. A kinetic and computational investigation of steric effects.	J Org Chem	2006
16489747	Leveraging enzyme structure-function relationships for functional inference and experimental design: the structure-function linkage database.	Biochemistry	2006
15759641	Representing structure-function relationships in mechanistically diverse enzyme superfamilies.	Pac Symp Biocomput	2005
12713273	A semiautomated approach to gene discovery through expressed sequence tag data mining: discovery of new human transporter genes.	AAPS PharmSci	2003
11674786	Acid-Catalyzed Breakdown of Alkoxide and Thiolate Ion Adducts of Benzylidene Meldrum's Acid, Methoxybenzylidene Meldrum's Acid and Thiomethoxybenzylidene Meldrum's Acid.	J Org Chem	1999

1 - 36 of 36

Neil Swainston

Institute of Systems, University of Liverpool

Career Start Year 2006

Number of shared co-authors 1

Lian Duan

Brown University

Career Start Year 2006

Number of shared co-authors 1

Thomas Clayton

Celgene/Bristol-Myers Squibb Corporation

Career Start Year 2004

Number of shared co-authors 1

Elena Evdokimova

University of Toronto

Career Start Year 2002

Number of shared co-authors 0

Heath E Klock

Merck & Co., Inc.

Career Start Year 2002

Number of shared co-authors 1

Dylan Chivian

Lawrence Berkeley National Laboratory

Career Start Year 2001

Number of shared co-authors 0

Stephen A McMahon

University of St Andrews

Career Start Year 1998

Number of shared co-authors 2

Iddo Friedberg

Iowa State University

Career Start Year 1997

Number of shared co-authors 13

Alexei Savchenko

University of Toronto

Career Start Year 1997

Number of shared co-authors 10

Hsiu-Ju Chiu

Joint Center for Structural Genomics

Career Start Year 1997

Number of shared co-authors 1

Ashley M Deacon

Accelero Biostructures Inc., USA XPose Therapeutics Inc.

Career Start Year 1996

Number of shared co-authors 1

Qingping Xu

Argonne National Laboratory

Career Start Year 1996

Number of shared co-authors 1

Alex Bateman

European Bioinformatics Institute (EMBL-EBI)

Career Start Year 1995

Number of shared co-authors 20

Lukasz Jaroszewski

University of California Riverside School of Medicine

Career Start Year 1995

Number of shared co-authors 5

Orly Dym

Weizmann Institute of Science

Career Start Year 1995

Number of shared co-authors 9

Jeremy D Selengut

Craig Venter Institute, 9704 Medical Center Drive

Career Start Year 1994

Number of shared co-authors 12

Youngchang Kim

Argonne National Laboratory

Career Start Year 1993

Number of shared co-authors 9

Marc-Andr?? Elsliger

Joint Center for Structural Genomics

Career Start Year 1989

Number of shared co-authors 2

Mitchell D Miller

Rice University

Career Start Year 1989

Number of shared co-authors 1

Wladek Minor

University of Virginia

Career Start Year 1989

Number of shared co-authors 14

P??r Nordlund

Karolinska Institutet, BioClinicum J6

Career Start Year 1989

Number of shared co-authors 9

Mark W Knuth

Joint Center for Structural Genomics

Career Start Year 1988

Number of shared co-authors 1

Adam Godzik

University of California Riverside

Career Start Year 1987

Number of shared co-authors 9

Scott A Lesley

Merck & Co., Inc.

Career Start Year 1987

Number of shared co-authors 10

Liisa Holm

Institute of Biotechnology, University of Helsinki

Career Start Year 1986

Number of shared co-authors 8

Daniel H Haft

National Center for Biotechnology Information, National Institutes of Health

Career Start Year 1985

Number of shared co-authors 18

Brian G Fox

University of Wisconsin-Madison

Career Start Year 1983

Number of shared co-authors 3

Andrei L Osterman

Sanford Burnham Prebys Medical Discovery Institute

Career Start Year 1980

Number of shared co-authors 17

Andrzej Joachimiak

Center for Structural Biology of Infectious Diseases, University of Chicago

Career Start Year 1979

Number of shared co-authors 12

Chris Sander

Broad Institute of MIT and Harvard

Career Start Year 1979

Number of shared co-authors 4

row(s) 1 - 30 of 30

Patricia C Babbitt

University of California san francisco

Co-authored papers 32

Steven C Almo

Albert Einstein College of Medicine

Co-authored papers 12

John A Gerlt

University of Illinois at Urbana-Champaign

Co-authored papers 7

Eyal Akiva

University of California san francisco

Co-authored papers 6

Thomas E Ferrin

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 6

Matthew P Jacobson

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 6

John H Morris

University of California san francisco

Co-authored papers 5

Conrad C Huang

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 5

Gemma L Holliday

European Bioinformatics Institute (EMBL-EBI)

Co-authored papers 5

Elaine C Meng

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 5

Jeffrey B Bonanno

Albert Einstein College of Medicine

Co-authored papers 4

Frank M Raushel

Texas A&M University, College Station

Co-authored papers 4

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 3

Ursula Pieper

University of California san francisco

Co-authored papers 3

Jennifer L Seffernick

University of Minnesota

Co-authored papers 3

Chakrapani Kalyanaraman

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 3

Brandan Hillerich

Cue BioPharma Inc.

Co-authored papers 3

Margaret E Glasner

Texas A&M University, College Station

Co-authored papers 3

Ronald D Seidel

Albert Einstein College of Medicine

Co-authored papers 3

Matthew W Vetting

Albert Einstein College of Medicine

Co-authored papers 3

Stephen K Burley

The State University of New Jersey

Co-authored papers 2

Yury Patskovsky

New York University Grossman School of Medicine

Co-authored papers 2

Nawar Al-Obaidi

Cardiovascular Research Unit, Newark Beth Israel Medical Center

Co-authored papers 2

Suwen Zhao

ShanghaiTech University, China iHuman Institute

Co-authored papers 2

Jungwook Kim

Gwangju Institute of Science and Technology

Co-authored papers 2

Karen N Allen

Boston University

Co-authored papers 2

J Michael Sauder

Eli Lilly and Co.

Co-authored papers 2

Heidi J Imker

Harvard Medical School

Co-authored papers 2

Christian J A Sigrist

Co-authored papers 1

Hongzhan Huang

Co-authored papers 1

1 - 30

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