Author details

Full Name

Peter K Sorger

Affiliation

ORCID

Career Start Year

1986

Papers

303

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37349501	High-plex immunofluorescence imaging and traditional histology of the same tissue section for discovering image-based biomarkers.		2023
36170403	Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data.	IEEE Trans Vis Comput Graph	2023
37602225	Paired evaluation of machine-learning models characterizes effects of confounders and outliers.	Patterns (N Y)	2023
37602216	Erratum: Paired evaluation of machine-learning models characterizes effects of confounders and outliers.	Patterns (N Y)	2023
37595065	A Hybrid Structure-Based Machine Learning Approach for Predicting Kinase Inhibition by Small Molecules.		2023
38014110	Cell Spotter (CSPOT): A machine-learning approach to automated cell spotting and quantification of highly multiplexed tissue images.		2023
38014067	SpatialCells: Automated Profiling of Tumor Microenvironments with Spatially Resolved Multiplexed Single-Cell Data.		2023
38014052	Multiplexed 3D Analysis of Cell Plasticity and Immune Niches in Melanoma.		2023
37986801	2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer.		2023
37716347	Metabolic modulation of mitochondrial mass during CD4<sup>+</sup> TÂ cell activation.	Cell Chem Biol	2023
37889813	Residency Octree: A Hybrid Approach for Scalable Web-Based Multi-Volume Rendering.		2023
37873453	ASCT2 is the primary serine transporter in cancer cells.	bioRxiv	2023
37873428	Resident memory T cell development is associated with AP-1 transcription factor upregulation across anatomical niches.		2023
37961235	Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter.		2023
37870091	Systematic Characterization of Antibody-Drug Conjugate Targets in Central Nervous System Tumors.		2023
36778477	Nociceptor neuroimmune interactomes reveal cell type- and injury-specific inflammatory pain pathways.	bioRxiv	2023
37473730	Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition.	Cell Syst	2023
36634707	Targeting TBK1 to overcome resistance to cancer immunotherapy.	Nature	2023
36700386	Mechanistic model of MAPK signaling reveals how allostery and rewiring contribute to drug resistance.		2023
37066161	Immune Profiling of Dermatologic Adverse Events from Checkpoint Blockade using Tissue Cyclic Immunofluorescence.		2023
36938926	Automated assembly of molecular mechanisms at scale from text mining and curated databases.	Mol Syst Biol	2023
37059105	Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma.		2023
37352344	Sequential apoptotic and multiplexed proteomic evaluation of single cancer cells.		2023
36920903	Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction.		2023
36669472	Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer.	Cell	2023
37542042	Proteomic profiling across breast cancer cell lines and models.	Sci Data	2023
34750536	Narrative online guides for the interpretation of digital-pathology images and tissue-atlas data.	Nature Biomedical Engineering	2022
36376301	Multiplexed and reproducible high content screening of live and fixed cells using Dye Drop.	Nat Commun	2022
35973991	Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma.	Nat Commun	2022
35972352	Stitching and registering highly multiplexed whole-slide images of tissues and tumors using ASHLAR.		2022
35842290	Drug independence and the curability of cancer by combination chemotherapy.		2022
36173860	Oncometabolite d-2HG alters T cell metabolism to impair CD8<sup>+</sup> T cell function.	Science	2022
35830470	Fides: Reliable trust-region optimization for parameter estimation of ordinary differential equation models.	PLoS Computational Biology	2022
36207580	A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses.	Commun Biol	2022
35737447	Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes.	Elife	2022
35617956	A human breast atlas integrating single-cell proteomics and transcriptomics.	Dev Cell	2022
35486732	Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy.	Science advances	2022
36192636	Single-sequence protein structure prediction using a language model and deep learning.	Nat Biotechnol	2022
35404441	The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution.	Cancer Discovery	2022
36425793	The impact of stage-related features in melanoma recurrence prediction: A machine learning approach.	JAAD Int	2022
36419822	Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients.	Cell Genomics	2022
36316482	Prediction of early-stage melanoma recurrence using clinical and histopathologic features.	NPJ Precis Oncol	2022
35045958	Predictable Clinical Benefits without Evidence of Synergy in Trials of Combination Therapies with Immune-Checkpoint Inhibitors.	Clinical Cancer Research	2022
34983746	Independent Drug Action in Combination Therapy: Implications for Precision Oncology.	Cancer Discovery	2022
35292783	Temporal and spatial topography of cell proliferation in cancer.	Nature Cell Biology	2022
35169116	Cancer patient survival can be parametrized to improve trial precision and reveal time-dependent therapeutic effects.	Nature Communications	2022
35149753	Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium.	Commun Biol	2022
35149709	Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer.	Nat Commun	2022
34606456	Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data.		2022
34824477	MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging.	Nat Methods	2022