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Author Details

Jesse S Boehm
Broad Institute of Harvard and MIT
2004
82
49
PMIDPaper TitleJournal TitlePublished Year
37612728Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.Genome Biol2023
37612728Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.Genome Biol2023
35084050Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.Prostate2022
35437317Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.Nat Cancer2022
36258042Author Correction: Massively parallel phenotyping of coding variants in cancer with Perturb-seq.Nat Biotechnol2022
35353015Cell Painting predicts impact of lung cancer variants.Mol Biol Cell2022
35058622Massively parallel phenotyping of coding variants in cancer with Perturb-seq.Nat Biotechnol2022
35085500Sparse dictionary learning recovers pleiotropy from human cell fitness screens.Cell Syst2022
35084050Implementation of a prostate cancer-specific targeted sequencing panel for credentialing of patient-derived cell lines and genomic characterization of patient samples.Prostate2022
35353015Cell Painting predicts impact of lung cancer variants.Mol Biol Cell2022
35437317Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.Nat Cancer2022
36258042Author Correction: Massively parallel phenotyping of coding variants in cancer with Perturb-seq.Nat Biotechnol2022
35085500Sparse dictionary learning recovers pleiotropy from human cell fitness screens.Cell Syst2022
35058622Massively parallel phenotyping of coding variants in cancer with Perturb-seq.Nat Biotechnol2022
34260938Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.Cell Rep2021
33753930A first-generation pediatric cancer dependency map.Nat Genet2021
34099491Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival.Cancer Res2021
34260938Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.Cell Rep2021
33500573Cancer research needs a better map.Nature2021
34723225Weekly SARS-CoV-2 screening of asymptomatic kindergarten to grade 12 students and staff helps inform strategies for safer in-person learning.Cell Rep Med2021
34930405Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects.Genome Biol2021
33753930A first-generation pediatric cancer dependency map.Nat Genet2021
33500573Cancer research needs a better map.Nature2021
34930405Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects.Genome Biol2021
34723225Weekly SARS-CoV-2 screening of asymptomatic kindergarten to grade 12 students and staff helps inform strategies for safer in-person learning.Cell Rep Med2021
34099491Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival.Cancer Res2021
32613204Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling.Nat Cancer2020
32696566The Cancer Dependency Map enables drug mechanism-of-action investigations.Mol Syst Biol2020
32613204Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling.Nat Cancer2020
33326793Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.Cell Rep2020
33326793Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.Cell Rep2020
32696566The Cancer Dependency Map enables drug mechanism-of-action investigations.Mol Syst Biol2020
30397176A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma.Clin Cancer Res2019
31862961Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.Nat Commun2019
30397176A Combination CDK4/6 and IGF1R Inhibitor Strategy for Ewing Sarcoma.Clin Cancer Res2019
30928774From cell lines to living biosensors: new opportunities to prioritize cancer dependencies using ex vivo tumor cultures.Curr Opin Genet Dev2019
30971823WRN helicase is a synthetic lethal target in microsatellite unstable cancers.Nature2019
30860482Renal medullary carcinomas depend upon <i>SMARCB1</i> loss and are sensitive to proteasome inhibition.Elife2019
30962421A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.Nat Commun2019
31068700Next-generation characterization of the Cancer Cell Line Encyclopedia.Nature2019
31862961Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets.Nat Commun2019
31068700Next-generation characterization of the Cancer Cell Line Encyclopedia.Nature2019
30860482Renal medullary carcinomas depend upon <i>SMARCB1</i> loss and are sensitive to proteasome inhibition.Elife2019
30971823WRN helicase is a synthetic lethal target in microsatellite unstable cancers.Nature2019
30962421A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.Nat Commun2019
30928774From cell lines to living biosensors: new opportunities to prioritize cancer dependencies using ex vivo tumor cultures.Curr Opin Genet Dev2019
29200198NetSig: network-based discovery from cancer genomes.Nat Methods2018
30550791Organoid Modeling of the Tumor Immune Microenvironment.Cell2018
30389920Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration.Nat Commun2018
29915188GeNets: a unified web platform for network-based genomic analyses.Nat Methods2018
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Collaborators

William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 54
David E Root
Broad Institute of Harvard and MIT
Co-authored papers 36
Todd R Golub
Broad Institute of MIT and Harvard
Co-authored papers 29
Francisca Vazquez
Broad Institute of MIT and Harvard
Co-authored papers 24
Aviad Tsherniak
Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard
Co-authored papers 21
Barbara A Weir
Janssen Research and Development LLC
Co-authored papers 16
Matthew Meyerson
Broad Institute
Co-authored papers 15
Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 15
Levi A Garraway
Broad Institute of Harvard and MIT
Co-authored papers 15
Pablo Tamayo
University of California San Diego
Co-authored papers 13
John G Doench
Co-authored papers 12
Federica Piccioni
Co-authored papers 11
Xiaoyun Wu
Co-authored papers 11
Eric S Lander
Vanderbilt-Ingram Cancer Center, Vanderbilt University
Co-authored papers 10
Jill P Mesirov
University of California San Diego
Co-authored papers 8
Aravind Subramanian
Co-authored papers 8
Bang Wong
Co-authored papers 8
Ian F Dunn
Co-authored papers 7
Glenn S Cowley
Broad Institute of Harvard and MIT
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Rameen Beroukhim
Co-authored papers 7
Eliezer M Van Allen
Dana-Farber Cancer Institute
Co-authored papers 7
Kimberly Stegmaier
Dana-Farber Cancer Institute
Co-authored papers 7
Serena J Silver
Co-authored papers 7
Paul A Clemons
Broad Institute
Co-authored papers 7
Stuart L Schreiber
Broad Institute
Co-authored papers 6
Gregory V Kryukov
Co-authored papers 6
Alice H Berger
Fred Hutchinson Cancer Research Center
Co-authored papers 6
Michael S Lawrence
Co-authored papers 6
Anna C Schinzel
Co-authored papers 6
Jordi Barretina
Co-authored papers 6
Release 1.2