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Author Details
Full Name
C David Allis
Affiliation
The Rockefeller University
ORCID
Career Start Year
1974
Papers
399
H Index
154
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36264143
A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition.
Cancer Discov
2023
37808786
Altered chromatin occupancy of patient-associated H4 mutants misregulate neuronal differentiation.
bioRxiv
2023
37491148
Histone bivalency regulates the timing of cerebellar granule cell development.
Genes Dev
2023
37626123
MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Nat Commun
2023
37650454
Correction: Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons.
J Cell Sci
2023
37261974
MLL3 regulates the <i>CDKN2A</i> tumor suppressor locus in liver cancer.
Elife
2023
36778390
Histone bivalency regulates the timing of cerebellar granule cell development.
bioRxiv
2023
36516747
Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation.
Cell Rep
2022
32711094
HAT discovery: Heading toward an elusive goal with a key biological assist.
Biochim Biophys Acta Gene Regul Mech
2021
33649601
Oncohistone mutations enhance chromatin remodeling and alter cell fates.
Nat Chem Biol
2021
33619101
Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation.
Proc Natl Acad Sci U S A
2021
34613815
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Sci Transl Med
2021
34580064
Histone H1 Mutations in Lymphoma: A Link(er) between Chromatin Organization, Developmental Reprogramming, and Cancer.
Cancer Res
2021
33986537
Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands.
Nat Genet
2021
34002060
The language of chromatin modification in human cancers.
Nat Rev Cancer
2021
33472068
HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies.
Cell Rep
2021
33412588
A Polycomb repressive complex is required for RNAi-mediated heterochromatin formation and dynamic distribution of nuclear bodies.
Nucleic Acids Res
2021
32396861
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response.
Cancer Cell
2020
33067396
Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression.
Proc Natl Acad Sci U S A
2020
32935098
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors.
bioRxiv
2020
32989154
Loss of UTX/KDM6A and the activation of FGFR3 converge to regulate differentiation gene-expression programs in bladder cancer.
Proc Natl Acad Sci U S A
2020
32699416
Histone H3.3 phosphorylation amplifies stimulation-induced transcription.
Nature
2020
32472103
In situ chromatin interactomics using a chemical bait and trap approach.
Nat Chem
2020
32268116
ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase.
Cell Metab
2020
31068593
Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.
Nat Commun
2019
31611394
PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor.
Proc Natl Acad Sci U S A
2019
31485078
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape.
Nature
2019
29395068
Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation.
Mol Cell
2018
30217363
Pursuing the Secrets of Histone Proteins: An Amazing Journey with a Remarkable Supporting Cast.
Cell
2018
30208392
Genetics, Biochemistry, and "Simple" Organisms Converge to Unlock Secrets in Histone Biology: The 2018 Albert Lasker Basic Medical Research Award.
JAMA
2018
29847798
NMDA Receptor Activation Underlies the Loss of Spinal Dorsal Horn Neurons and the Transition to Persistent Pain after Peripheral Nerve Injury.
Cell Rep
2018
30374167
Structure-guided development of YEATS domain inhibitors by targeting Ï¿-Ï¿-Ï¿ stacking.
Nat Chem Biol
2018
30315258
ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup.
Nat Commun
2018
29358330
Histone variant H3.3-mediated chromatin remodeling is essential for paternal genome activation in mouse preimplantation embryos.
J Biol Chem
2018
29547264
Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".
ACS Chem Biol
2018
29662175
Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.
Nat Cell Biol
2018
29395070
Engineering of a Histone-Recognition Domain in Dnmt3a Alters the Epigenetic Landscape and Phenotypic Features of Mouse ESCs.
Mol Cell
2018
29395069
Greater Than the Sum of Parts: Complexity of the Dynamic Epigenome.
Mol Cell
2018
27864305
Oncogenic Mechanisms of Histone H3 Mutations.
Cold Spring Harb Perspect Med
2017
28138149
SWI/SNF complex in cancer.
Nat Genet
2017
28108335
Tryptase-catalyzed core histone truncation: AÂ novel epigenetic regulatory mechanism in mast cells.
J Allergy Clin Immunol
2017
28241141
ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia.
Nature
2017
29030587
NatD promotes lung cancer progression by preventing histone H4 serine phosphorylation to activate Slug expression.
Nat Commun
2017
28536244
Opinion: On being an advisor to today's junior scientists.
Proc Natl Acad Sci U S A
2017
28770850
Elsässer et al. reply.
Nature
2017
28767641
ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference.
Nature
2017
28823556
Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition.
Cell
2017
27924077
Metabolic regulation of gene expression through histone acylations.
Nat Rev Mol Cell Biol
2017
28067913
Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.
Nat Genet
2017
27103431
YEATS2 is a selective histone crotonylation reader.
Cell Res
2016
1 - 50 of 399
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