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Author Details

Todd R Golub
Broad Institute of MIT and Harvard
1989
308
153
PMIDPaper TitleJournal TitlePublished Year
36711455An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies.bioRxiv2023
37794185The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.Nature2023
37612728Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.Genome Biol2023
36711603A nanoparticle priming agent reduces cellular uptake of cell-free DNA and enhances the sensitivity of liquid biopsies.bioRxiv2023
36711455An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies.bioRxiv2023
37205492Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.bioRxiv2023
37453661FDX1 regulates cellular protein lipoylation through direct binding to LIAS.J Biol Chem2023
36945501Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030.medRxiv2023
37106072Single duplex DNA sequencing with CODEC detects mutations with high sensitivity.Nat Genet2023
37794185The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.Nature2023
37612728Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.Genome Biol2023
37453661FDX1 regulates cellular protein lipoylation through direct binding to LIAS.J Biol Chem2023
36945501Circulating tumor DNA association with residual cancer burden after neoadjuvant chemotherapy in triple-negative breast cancer in TBCRC 030.medRxiv2023
37106072Single duplex DNA sequencing with CODEC detects mutations with high sensitivity.Nat Genet2023
37205492Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma.bioRxiv2023
36711603A nanoparticle priming agent reduces cellular uptake of cell-free DNA and enhances the sensitivity of liquid biopsies.bioRxiv2023
34591958Duplex-Repair enables highly accurate sequencing, despite DNA damage.Nucleic Acids Res2022
36305736BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.Cancer Discov2022
35759080Proceedings of the fifth international Molecular Pathological Epidemiology (MPE) meeting.Cancer Causes Control2022
35821277Publisher Correction: DNA-based copy number analysis confirms genomic evolution of PDX models.NPJ Precis Oncol2022
35437317Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.Nat Cancer2022
36127368Systematic profiling of conditional degron tag technologies for target validation studies.Nat Commun2022
35301450Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth.Nat Biomed Eng2022
35298263Copper induces cell death by targeting lipoylated TCA cycle proteins.Science2022
34984433Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine.Neuro Oncol2022
34591958Duplex-Repair enables highly accurate sequencing, despite DNA damage.Nucleic Acids Res2022
35437317Phosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.Nat Cancer2022
35759080Proceedings of the fifth international Molecular Pathological Epidemiology (MPE) meeting.Cancer Causes Control2022
35821277Publisher Correction: DNA-based copy number analysis confirms genomic evolution of PDX models.NPJ Precis Oncol2022
36305736BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma.Cancer Discov2022
36127368Systematic profiling of conditional degron tag technologies for target validation studies.Nat Commun2022
34984433Liquid biopsy detection of genomic alterations in pediatric brain tumors from cell-free DNA in peripheral blood, CSF, and urine.Neuro Oncol2022
35301450Massively parallel enrichment of low-frequency alleles enables duplex sequencing at low depth.Nat Biomed Eng2022
35298263Copper induces cell death by targeting lipoylated TCA cycle proteins.Science2022
34253920Genome-scale screens identify factors regulating tumor cell responses to natural killer cells.Nat Genet2021
34179825FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS.Nat Cancer2021
33753930A first-generation pediatric cancer dependency map.Nat Genet2021
33883167Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer.Cancer Discov2021
33510483Noncanonical open reading frames encode functional proteins essential for cancer cell survival.Nat Biotechnol2021
34260938Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.Cell Rep2021
33505028Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.Nature2021
34253920Genome-scale screens identify factors regulating tumor cell responses to natural killer cells.Nat Genet2021
33500573Cancer research needs a better map.Nature2021
34732899Publisher Correction: A metastasis map of human cancer cell lines.Nature2021
35122065Author Correction: Fatty acid synthesis is required for breast cancer brain metastasis.Nat Cancer2021
33883167Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer.Cancer Discov2021
33510483Noncanonical open reading frames encode functional proteins essential for cancer cell survival.Nat Biotechnol2021
33505028Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition.Nature2021
33753930A first-generation pediatric cancer dependency map.Nat Genet2021
33500573Cancer research needs a better map.Nature2021
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Collaborators

Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
Co-authored papers 54
Eric S Lander
Vanderbilt-Ingram Cancer Center, Vanderbilt University
Co-authored papers 43
Matthew Meyerson
Broad Institute
Co-authored papers 39
Jesse S Boehm
Broad Institute of Harvard and MIT
Co-authored papers 29
David E Root
Broad Institute of Harvard and MIT
Co-authored papers 29
Kimberly Stegmaier
Dana-Farber Cancer Institute
Co-authored papers 28
Aravind Subramanian
Co-authored papers 28
William C Hahn
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Co-authored papers 27
Levi A Garraway
Broad Institute of Harvard and MIT
Co-authored papers 26
Rameen Beroukhim
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Michael S Lawrence
Co-authored papers 26
Francisca Vazquez
Broad Institute of MIT and Harvard
Co-authored papers 25
Pablo Tamayo
University of California San Diego
Co-authored papers 24
Benjamin L Ebert
Co-authored papers 24
Aviad Tsherniak
Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard
Co-authored papers 22
Stacey Gabriel
Broad Institute of MIT and Harvard
Co-authored papers 21
Stefano Monti
Co-authored papers 21
Jun Lu
Yale University
Co-authored papers 18
Donna Neuberg
Co-authored papers 18
Jill P Mesirov
University of California San Diego
Co-authored papers 17
Stuart L Schreiber
Broad Institute
Co-authored papers 17
Massimo Loda
Weill Medical College of Cornell University
Co-authored papers 16
Carrie Sougnez
The Broad Institute of Harvard and MIT
Co-authored papers 16
Wendy Winckler
Co-authored papers 15
Kristian Cibulskis
Co-authored papers 14
William R Sellers
Co-authored papers 14
Barbara A Weir
Janssen Research and Development LLC
Co-authored papers 14
Bang Wong
Co-authored papers 13
Daniel Auclair
Co-authored papers 13
Scott L Carter
Co-authored papers 13
Release 1.2