Author details

Full Name

Symen Ligthart

Affiliation

ORCID

Career Start Year

2014

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37582864	Ferroptosis and pyroptosis signatures in critical COVID-19 patients.	Cell Death Differ	2023
35137143	Thyroid Function and the Risk of Prediabetes and Type 2 Diabetes.	Journal of Clinical Endocrinology and Metabolism	2022
35459240	Genetic analysis of over half a million people characterises C-reactive protein loci.	Nat Commun	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35790731	Author Correction: Genetic analysis of over half a million people characterises C-reactive protein loci.	Nat Commun	2022
35094551	American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease.	Circulation	2022
33079133	Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study.	JAMA Psychiatry	2021
34091768	Meta-analysis of epigenome-wide association studies of carotid intima-media thickness.	Eur J Epidemiol	2021
34245042	Genetic susceptibility, obesity and lifetime risk of type 2 diabetes: The ARIC study and Rotterdam Study.	Diabet Med	2021
33214188	Lifetime risk to progress from pre-diabetes to type 2 diabetes among women and men: comparison between American Diabetes Association and World Health Organization diagnostic criteria.	BMJ Open Diabetes Res Care	2020
33367543	A Mendelian randomization of Î³' and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke.	Blood	2020
32755526	Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis.	Twin Res Hum Genet	2020
31197173	An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.	Nat Commun	2019
31578548	Commentary: CRP and schizophrenia: cause, consequence or confounding?	International Journal of Epidemiology	2019
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018
30388399	Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.	Am J Hum Genet	2018
29617535	Association of Methylation Signals With Incident Coronary Heart Disease in an Epigenome-Wide Assessment of Circulating Tumor Necrosis Factor Î±.	JAMA Cardiol	2018
28224192	Serum magnesium and the risk of prediabetes: a population-based cohort study.	Diabetologia	2017
28428221	Circulating Levels of Interleukin 1-Receptor Antagonist and Risk of Cardiovascular Disease: Meta-Analysis of Six Population-Based Cohorts.	Arterioscler Thromb Vasc Biol	2017
28721436	Age at natural menopause and risk of type 2 diabetes: a prospective cohort study.	Diabetologia	2017
28338987	Gamma-glutamyltransferase levels, prediabetes and type 2 diabetes: a Mendelian randomization study.	Int J Epidemiol	2017
29198723	DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation.	Am J Hum Genet	2017
27787621	ADAMTS13 activity as a novel risk factor for incident type 2 diabetes mellitus: a population-based cohort study.	Diabetologia	2017
28031419	Serum Levels of Apolipoproteins and Incident Type 2 Diabetes: A Prospective Cohort Study.	Diabetes Care	2017
28107422	Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.	PLoS One	2017
28258520	Novel inflammatory markers for incident pre-diabetes and type 2 diabetes: the Rotterdam Study.	Eur J Epidemiol	2017
27686165	Thyroid function and risk of type 2 diabetes: a population-based prospective cohort study.	BMC Med	2016
27433939	Obesity and Life Expectancy with and without Diabetes in Adults Aged 55 Years and Older in the Netherlands: A Prospective Cohort Study.	PLoS Med	2016
27149122	Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure.	PLoS Genet	2016
27146363	The role of global and regional DNA methylation and histone modifications in glycemic traits and type 2 diabetes: A systematic review.	Nutr Metab Cardiovasc Dis	2016
27286809	Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.	BMC Genomics	2016
27040690	DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.	Am J Hum Genet	2016
26861414	Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns.	Nat Commun	2016
26825526	Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes.	Diabetologia	2016
26585369	Gait characteristics in older adults with diabetes and impaired fasting glucose: The Rotterdam Study.	J Diabetes Complications	2016
26575606	Lifetime risk of developing impaired glucose metabolism and eventual progression from prediabetes to type 2 diabetes: a prospective cohort study.	Lancet Diabetes Endocrinol	2016
26487741	Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors.	Circ Res	2016
27955697	DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.	Genome Biol	2016
27656045	Metabolic syndrome is related to polyneuropathy and impaired peripheral nerve function: a prospective population-based cohort study.	J Neurol Neurosurg Psychiatry	2016
26147588	Vitamin D and C-Reactive Protein: A Mendelian Randomization Study.	PLoS One	2015
25768928	Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein.	PLoS One	2015
25953786	Incremental predictive value of 152 single nucleotide polymorphisms in the 10-year risk prediction of incident coronary heart disease: the Rotterdam Study.	Int J Epidemiol	2015
26015811	Tobacco smoking is associated with methylation of genes related to coronary artery disease.	Clin Epigenetics	2015
24885632	Soluble Flt1 and placental growth factor are novel determinants of newborn thyroid (dys)function: the generation R study.	J Clin Endocrinol Metab	2014
24981077	Pleiotropic genes for metabolic syndrome and inflammation.	Mol Genet Metab	2014
25341801	EN-RAGE: a novel inflammatory marker for incident coronary heart disease.	Arterioscler Thromb Vasc Biol	2014