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| 37992152 | Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency. | | 2023 |
| 35918471 | Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency. | Commun Biol | 2022 |
| 33206168 | Glucagon Receptor Inhibition Reduces Hyperammonemia and Lethality in Male Mice with Urea Cycle Disorder. | Endocrinology | 2021 |
| 32554468 | Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells. | Journal of Biological Chemistry | 2020 |
| 31843957 | Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice. | Journal of Lipid Research | 2020 |
| 31836692 | Clinical and Molecular Prevalence of Lipodystrophy in an Unascertained Large Clinical Care Cohort. | Diabetes | 2020 |
| 32646941 | Angiopoietin-like protein 3 governs LDL-cholesterol levels through endothelial lipase-dependent VLDL clearance. | Journal of Lipid Research | 2020 |
| 30992050 | RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy. | Skeletal Muscle | 2019 |
| 31676859 | Loss of ZnT8 function protects against diabetes by enhanced insulin secretion. | Nature Genetics | 2019 |
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| 30582457 | Hepatic Glucagon Signaling Regulates PCSK9 and Low-Density Lipoprotein Cholesterol. | Circulation Research | 2019 |
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| 30920583 | The Liver-α-Cell Axis and Type 2 Diabetes. | Endocrine Reviews | 2019 |
| 31500834 | Heterogeneity of human pancreatic β-cells. | Molecular Metabolism | 2019 |
| 30938753 | Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition. | Endocrinology | 2019 |
| 29358393 | Increased thermogenesis by a noncanonical pathway in ANGPTL3/8-deficient mice. | Proceedings of the National Academy of Sciences of the United States of America | 2018 |
| 28755409 | A first-in-human pharmacodynamic and pharmacokinetic study of a fully human anti-glucagon receptor monoclonal antibody in normal healthy volunteers. | Diabetes, Obesity and Metabolism | 2018 |
| 29032602 | Muscle-specific differences in expression and phosphorylation of the Janus kinase 2/Signal Transducer and Activator of Transcription 3 following long-term mechanical ventilation and immobilization in rats. | Acta Physiologica | 2018 |
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| 30380031 | Gene Signature of the Human Pancreatic ε Cell. | Endocrinology | 2018 |
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| 29899519 | Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes. | Nat Commun | 2018 |
| 30038024 | Mice harboring the human R138X loss-of-function mutation have increased insulin secretory capacity. | Proceedings of the National Academy of Sciences of the United States of America | 2018 |
| 29562163 | A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease. | N Engl J Med | 2018 |
| 29522819 | Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells. | Cellular Signalling | 2018 |
| 29555772 | Glucagon contributes to liver zonation. | Proceedings of the National Academy of Sciences of the United States of America | 2018 |
| 29698569 | Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction. | Hepatology | 2018 |
| 28115707 | Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice. | Proceedings of the National Academy of Sciences of the United States of America | 2017 |
| 28600283 | Inhibition of PCSK9 does not improve lipopolysaccharide-induced mortality in mice. | Journal of Lipid Research | 2017 |
| 28723334 | ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia. | New England Journal of Medicine | 2017 |
| 28591637 | Amino Acid Transporter Slc38a5 Controls Glucagon Receptor Inhibition-Induced Pancreatic α Cell Hyperplasia in Mice. | | 2017 |
| 28452368 | Activin A more prominently regulates muscle mass in primates than does GDF8. | Nature Communications | 2017 |
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| 28413163 | ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance. | Journal of Lipid Research | 2017 |
| 28323959 | Insulin and Glucagon: Partners for Life. | Endocrinology | 2017 |
| 28321233 | Heterogeneity of the Pancreatic Beta Cell. | Frontiers in Genetics | 2017 |
| 28650342 | Inflammatory Ly6Chi monocytes and their conversion to M2 macrophages drive atherosclerosis regression. | J Clin Invest | 2017 |
| 28204173 | ANGPTL8 Blockade With a Monoclonal Antibody Promotes Triglyceride Clearance, Energy Expenditure, and Weight Loss in Mice. | Endocrinology | 2017 |
| 28143927 | Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition. | Proceedings of the National Academy of Sciences of the United States of America | 2017 |
| 28132887 | PC1/3 Deficiency Impacts Pro-opiomelanocortin Processing in Human Embryonic Stem Cell-Derived Hypothalamic Neurons. | Stem Cell Reports | 2017 |
| 27959690 | Variants in ANGPTL4 and the Risk of Coronary Artery Disease. | N Engl J Med | 2016 |
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| 27667665 | RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes. | | 2016 |
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