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Author Details

Laura Acquasaliente
Department of Pharmaceutical and Pharmacological Sciences, University of Padova
2012
29
12
PMIDPaper TitleJournal TitlePublished Year
37209594The role of high molecular weight hyaluronic acid in mucoadhesion on an ocular surface model.J Mech Behav Biomed Mater2023
37879145A novel genetically-encoded bicyclic peptide inhibitor of human urokinase-type plasminogen activator with better cross-reactivity toward the murine orthologue.Bioorg Med Chem2023
37924304From haemadin to haemanorm: Synthesis and characterization of full-length haemadin from the leech Haemadipsa sylvestris and of a novel bivalent, highly potent thrombin inhibitor (haemanorm).Protein Sci2023
37311533Aerosolized sulfated hyaluronan derivatives prolong the survival of K18 ACE2 mice infected with a lethal dose of SARS-CoV-2.Eur J Pharm Sci2023
35052783NOG-Derived Peptides Can Restore Neuritogenesis on a CRASH Syndrome Cell Model.Biomedicines2022
35701444Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation.Sci Rep2022
36614141The Role of Proteolysis in Amyloidosis.Int J Mol Sci2022
35954311Preliminary Discovery of Small Molecule Inhibitors of Epidermal Growth Factor Receptor (EGFR) That Bind to the Extracellular Domain.Cancers (Basel)2022
34199427Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC.Int J Mol Sci2021
33920144Von Willebrand Factor Multimers and the Relaxation Response: A One-Year Study.Entropy (Basel)2021
33727531Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen.Nat Commun2021
33803867Sperm Cholesterol Content Modifies Sperm Function and TRPV1-Mediated Sperm Migration.Int J Mol Sci2021
34712402A conserved Neurite Outgrowth and Guidance motif with biomimetic potential in neuronal Cell Adhesion Molecules.Comput Struct Biotechnol J2021
33033332Endocrine disruption of vitamin D activity by perfluoro-octanoic acid (PFOA).Sci Rep2020
30670733Effects of point mutations in the binding pocket of the mouse major urinary protein MUP20 on ligand affinity and specificity.Sci Rep2019
30992526Probing prothrombin structure by limited proteolysis.Sci Rep2019
30403786Endocrine Disruption of Androgenic Activity by Perfluoroalkyl Substances: Clinical and Experimental Evidence.J Clin Endocrinol Metab2019
29230873Noncoded amino acids in protein engineering: Structure-activity relationship studies of hirudin-thrombin interaction.Biotechnol Appl Biochem2018
30466070Lupus anticoagulant identifies two distinct groups of patients with different antibody patterns.Thromb Res2018
29511224Interplay between conformational selection and zymogen activation.Sci Rep2018
28684417Non-canonical proteolytic activation of human prothrombin by subtilisin from <i>Bacillus subtilis</i> may shift the procoagulant-anticoagulant equilibrium toward thrombosis.J Biol Chem2017
28490758Identifying conformational changes with site-directed spin labeling reveals that the GTPase domain of HydF is a molecular switch.Sci Rep2017
28963346Onconase dimerization through 3D domain swapping: structural investigations and increase in the apoptotic effect in cancer cells.Biochem J2017
27347732Loop Electrostatics Asymmetry Modulates the Preexisting Conformational Equilibrium in Thrombin.Biochemistry2016
27818145A MICU1 Splice Variant Confers High Sensitivity to the Mitochondrial Ca<sup>2+</sup> Uptake Machinery of Skeletal Muscle.Mol Cell2016
27760842Molecular mapping of α-thrombin (αT)/β2-glycoprotein I (β2GpI) interaction reveals how β2GpI affects αT functions.Biochem J2016
26001728Thrombin inhibits the anti-myeloperoxidase and ferroxidase functions of ceruloplasmin: relevance in rheumatoid arthritis.Free Radic Biol Med2015
23578283β2 -Glycoprotein I binds to thrombin and selectively inhibits the enzyme procoagulant functions.J Thromb Haemost2013
22635233Circulating β2 glycoprotein I-IgG anti-β2 glycoprotein I immunocomplexes in patients with definite antiphospholipid syndrome.Lupus2012
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Collaborators

Vincenzo De Filippis
Department of Pharmaceutical and Pharmacological Sciences, University of Padua
Co-authored papers 19
Federico Uliana
Institute of Biochemistry, ETH Zurich
Co-authored papers 2
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Rodolfo Ciuffa
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Bernd Wollscheid
ETH Zurich
Co-authored papers 1
Ulrich Auf dem Keller
Technical University of Denmark
Co-authored papers 1
Sandra Goetze
ETH Zurich
Co-authored papers 1
Matej Vizovi??ek
Jozef Stefan Institute
Co-authored papers 1
Rosario Rizzuto
Co-authored papers 1
Luis Martinez-Sobrido
Texas Biomedical Research Institute
Co-authored papers 1
Andrea Fossati
J. David Gladstone Institutes
Co-authored papers 1
Fabian Frommelt
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 1
Matthias Gstaiger
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
Release 1.2