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Author Details

Andrew V Kossenkov
The Wistar Institute
2003
210
55
Sarah J Ratcliffe (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36863485Elevated iNOS and 3'-nitrotyrosine in Kaposi's Sarcoma tumors and mouse model.Tumour Virus Res2023
37889078The three-dimensional structure of the EBV genome plays a crucial role in regulating viral gene expression in EBVaGC.Nucleic Acids Res2023
37609144Plasma Glycomic Markers of Accelerated Biological Aging During Chronic HIV Infection.bioRxiv2023
37606370Decitabine disrupts EBV genomic epiallele DNA methylation patterns around CTCF binding sites to increase chromatin accessibility and lytic transcription in gastric cancer.mBio2023
37723305Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer.Nat Cancer2023
36993171Leukemia core transcriptional circuitry is a sparsely interconnected hierarchy stabilized by incoherent feed-forward loops.bioRxiv2023
37149684Type I interferon response in astrocytes promotes brain metastasis by enhancing monocytic myeloid cell recruitment.Nat Commun2023
37377614Targeting Fatty Acid Reprogramming Suppresses CARM1-expressing Ovarian Cancer.Cancer Res Commun2023
36975214The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9.Antimicrob Agents Chemother2023
37205503Age-related increases in IGFBP2 increase melanoma cell invasion and lipid synthesis.bioRxiv2023
37140445An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.Cancer Discov2023
37095257The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses.Oncogene2023
36999023Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge.Front Immunol2023
37328686Correction: NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment.Oncogene2023
36963401Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis.Cancer Cell2023
37461649PARP1 Inhibition Halts EBV+ Lymphoma Progression by Disrupting the EBNA2/MYC Axis.bioRxiv2023
36749725Common activities and predictive gene signature identified for genetic hypomorphs of TP53.Proc Natl Acad Sci U S A2023
36548516Syntaphilin Regulates Neutrophil Migration in Cancer.Cancer Immunol Res2023
36778367Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells.Res Sq2023
36911698Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression <i>in vivo</i>.Front Immunol2023
36712010The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses.Res Sq2023
36711814Dasatinib Resensitizes MAPK Inhibitor Efficacy in Standard-of-Care Relapsed Melanomas.bioRxiv2023
36707623Correction: NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment.Oncogene2023
36824975Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to <i>LMNA</i> cardiomyopathy.bioRxiv2023
36892943Intercellular hif1α reprograms mammary progenitors and myeloid immune evasion to drive high-risk breast lesions.J Clin Invest2023
34432273Functional Annotation of MicroRNAs Using Existing Resources.Methods Mol Biol2022
35650435Stromal changes in the aged lung induce an emergence from melanoma dormancy.Nature2022
35726891KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer.Cancer Immunol Res2022
35726818Mechanisms regulating transitory suppressive activity of neutrophils in newborns: PMNs-MDSCs in newborns.J Leukoc Biol2022
35723626IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma.Cancer Discov2022
35421198The nuclear lamina binds the EBV genome during latency and regulates viral gene expression.PLoS Pathog2022
35420632Telomere dysfunction implicates POT1 in patients with idiopathic pulmonary fibrosis.J Exp Med2022
35851616ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16<sup>INK4a</sup> levels.Nat Cell Biol2022
35552618Tumor-Derived Lysophosphatidic Acid Blunts Protective Type I Interferon Responses in Ovarian Cancer.Cancer Discov2022
35354906NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment.Oncogene2022
36028493DAXX-ATRX regulation of p53 chromatin binding and DNA damage response.Nat Commun2022
36261012Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis.Cell Rep2022
36223343Mitochondrial fitness and cancer risk.PLoS One2022
36385526Ferroptosis of tumour neutrophils causes immune suppression in cancer.Nature2022
36344556The NOGO receptor NgR2, a novel αVβ3 integrin effector, induces neuroendocrine differentiation in prostate cancer.Sci Rep2022
36083892The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer.Sci Immunol2022
35188070Small extracellular vesicle-mediated <i>ITGB6</i> siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells.Cancer Biol Ther2022
35039491The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity.Nat Commun2022
35177476Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability.Proc Natl Acad Sci U S A2022
35022320BAMM (BRAF Autophagy and MEK Inhibition in Melanoma): A Phase I/II Trial of Dabrafenib, Trametinib, and Hydroxychloroquine in Advanced BRAFV600-mutant Melanoma.Clin Cancer Res2022
33414169Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth.Cancer Res2021
33883224Defective Epstein-Barr Virus Genomes and Atypical Viral Gene Expression in B-Cell Lines Derived from Multiple Myeloma Patients.J Virol2021
33795874m<sup>6</sup>A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype.Nat Cell Biol2021
33741967Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway.Nat Commun2021
33566112Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice.J Exp Med2021
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Collaborators

The Wistar Institute
Co-authored papers 46
Co-authored papers 37
The Wistar Institute
Co-authored papers 17
Ellen and Ronald Caplan Cancer Center, The Wistar Institute
Co-authored papers 13
Wistar Institute
Co-authored papers 13
Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine
Co-authored papers 12
The College of New Jersey
Co-authored papers 7
University of Pennsylvania School of Medicine
Co-authored papers 6
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Co-authored papers 6
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 5
Co-authored papers 5
Johns Hopkins University School of Medicine
Co-authored papers 5
Center for Free Radical and Antioxidant Health, University of Pittsburgh
Co-authored papers 4
Co-authored papers 4
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 4
Wistar Institute
Co-authored papers 4
Co-authored papers 4
Co-authored papers 3
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 3
UCL Queen Square Institute of Neurology
Co-authored papers 3
University of Washington School of Medicine
Co-authored papers 3
Co-authored papers 3
The Wistar Institute
Co-authored papers 3
National Institute on Aging, National Institutes of Health
Co-authored papers 3
University of Virginia
Co-authored papers 3
Co-authored papers 3
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
National Institute on Aging, National Institutes of Health
Co-authored papers 2
Co-authored papers 2