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Author Details

Hiroaki Hirata
Nagoya University Graduate School of Medicine
2004
60
23
PMIDPaper TitleJournal TitlePublished Year
36852278Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers.iScience2023
36994099Editorial: Multicellularity: Views from cellular signaling and mechanics.Front Cell Dev Biol2023
34073333Involvement of Autophagy in Rat Tail Static Compression-Induced Intervertebral Disc Degeneration and Notochordal Cell Disappearance.Int J Mol Sci2021
34858971Anti-Malignant Effect of Tensile Loading to Adherens Junctions in Cutaneous Squamous Cell Carcinoma Cells.Front Cell Dev Biol2021
34440595Sphingosine-1-Phosphate Induces ATP Release via Volume-Regulated Anion Channels in Breast Cell Lines.Life (Basel)2021
33194512Cell mechanosensing underlies homeostasis of multicellular systems.Biophys Physicobiol2020
32093160MMP24 as a Target of YAP is a Potential Prognostic Factor in Cancer Patients.Bioengineering (Basel)2020
33225242Coordination between Cell Motility and Cell Cycle Progression in Keratinocyte Sheets via Cell-Cell Adhesion and Rac1.iScience2020
31480541DMPK is a New Candidate Mediator of Tumor Suppressor p53-Dependent Cell Death.Molecules2019
30204447Tensile Loads on Tethered Actin Filaments Induce Accumulation of Cell Adhesion-Associated Proteins in Vitro.Langmuir2019
28686514Substrate rigidity-dependent positive feedback regulation between YAP and ROCK2.Cell Adh Migr2018
30101371Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms.Clin Transl Med2018
30227869The factors of deterioration in long-term clinical course of lumbar spinal canal stenosis after successful conservative treatment.J Orthop Surg Res2018
30404732Planar compression of extracellular substrates induces S phase arrest via ATM-independent CHK2 activation.Biochem Biophys Res Commun2018
30384551Dopamine and Serotonin Receptors Cooperatively Modulate Pacemaker Activity of Intestinal Cells of Cajal.Chin J Physiol2018
29462067Postoperative Walking Ability of Non-ambulatory Cervical Myelopathy Patients.Spine (Phila Pa 1976)2018
27525538Predictive Risk Factors of Cervical Spine Instabilities in Rheumatoid Arthritis: A Prospective Multicenter Over 10-Year Cohort Study.Spine (Phila Pa 1976)2017
28191463Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression.Biomed Res Int2017
28406163Actomyosin contractility provokes contact inhibition in E-cadherin-ligated keratinocytes.Sci Rep2017
28321404Cell and Molecular Mechanics in Health and Disease.Biomed Res Int2017
27924570Quantifying Tensile Force and ERK Phosphorylation on Actin Stress Fibers.Methods Mol Biol2017
27779604The Prediction and Prevention of Dysphagia After Occipitospinal Fusion by Use of the S-line (Swallowing Line).Spine (Phila Pa 1976)2017
27029899Association between tensin 1 and p130Cas at focal adhesions links actin inward flux to cell migration.Biol Open2016
28078303Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling.Biomed Res Int2016
27876065Expression of adiponectin receptors in human and rat intervertebral disc cells and changes in receptor expression during disc degeneration using a rat tail temporary static compression model.J Orthop Surg Res2016
27885186[p130Cas-Mediated Regulation of Mechanical Functions of Cells.]Clin Calcium2016
27454536Preliminary Evaluation of the Pathomechanisms of Dysphagia After Occipitospinal Fusion: Kinematic Analysis by Videofluoroscopic Swallowing Study.Spine (Phila Pa 1976)2016
27528401MEKK1-dependent phosphorylation of calponin-3 tunes cell contractility.J Cell Sci2016
24965068Non-channel mechanosensors working at focal adhesion-stress fiber complex.Pflugers Arch2015
26479219A novel role of actomyosin bundles in ERK signaling.Commun Integr Biol2015
25702895Cell surface receptors: rapid quantification of live cell receptors using bioluminescence in a flow-based microfluidic device (small 8/2015).Small2015
25550404Actomyosin bundles serve as a tension sensor and a platform for ERK activation.EMBO Rep2015
25546513Functional impact of integrin α5β1 on the homeostasis of intervertebral discs: a study of mechanotransduction pathways using a novel dynamic loading organ culture system.Spine J2015
25608921Mechanics of epithelial closure over non-adherent environments.Nat Commun2015
25336403Rapid quantification of live cell receptors using bioluminescence in a flow-based microfluidic device.Small2015
24472667Notochordal cell disappearance and modes of apoptotic cell death in a rat tail static compression-induced disc degeneration model.Arthritis Res Ther2014
25142525Actin flow and talin dynamics govern rigidity sensing in actin-integrin linkage through talin extension.J R Soc Interface2014
25081617Molecular mechanisms underlying the force-dependent regulation of actin-to-ECM linkage at the focal adhesions.Prog Mol Biol Transl Sci2014
24928898Displacement of p130Cas from focal adhesions links actomyosin contraction to cell migration.J Cell Sci2014
24558457Accelerated development of cervical spine instabilities in rheumatoid arthritis: a prospective minimum 5-year cohort study.PLoS One2014
24722239Biophysical properties of intrinsically disordered p130Cas substrate domain--implication in mechanosensing.PLoS Comput Biol2014
24662565p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion.J Cell Biol2014
24626190Design and construction of an equibiaxial cell stretching system that is improved for biochemical analysis.PLoS One2014
24647813Loss of p53 enhances NF-κB-dependent lamellipodia formation.J Cell Physiol2014
24285589A rat tail temporary static compression model reproduces different stages of intervertebral disc degeneration with decreased notochordal cell phenotype.J Orthop Res2014
24292420Epithelial bridges maintain tissue integrity during collective cell migration.Nat Mater2014
24452377Force-dependent vinculin binding to talin in live cells: a crucial step in anchoring the actin cytoskeleton to focal adhesions.Am J Physiol Cell Physiol2014
23192951Fas ligand plays an important role for the production of pro-inflammatory cytokines in intervertebral disc nucleus pulposus cells.J Orthop Res2013
29252520Intraosseous Epidermoid Cyst in the Femur After an Open Fracture: A Case Report.JBJS Case Connect2013
24302570Cytoplasmic translocation of the retinoblastoma protein disrupts sarcomeric organization.Elife2013
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Collaborators

Yasuhiro Sawada
National Rehabilitation Center for Persons with Disabilities
Co-authored papers 10
Hiroaki Machiyama
Tokyo Medical University
Co-authored papers 5
Mallur S Madhusudhan
Indian Institute of Science Education and Research Pune
Co-authored papers 1
Takashi Ohe
Locomotive Syndrome Research Institute, Nadogaya Hospital
Co-authored papers 1
Rong Gao
ShanghaiTech University
Co-authored papers 1
Christopher W V Hogue
National University of Singapore
Co-authored papers 1
Yasushi Ishihama
Graduate School of Pharmaceutical Sciences, Kyoto University
Co-authored papers 1
Soumya Ranganathan
and Blood Institute, National Institutes of Health
Co-authored papers 1
Ruchuan Liu
College of Physics, Chongqing University
Co-authored papers 1
Neelesh Soni
Indian Institute of Science Education and Research Pune
Co-authored papers 1
Fei Wu
National University of Singapore
Co-authored papers 1
Kinya Hotta
Genetech Biotechnology Pte Ltd.
Co-authored papers 1
Release 1.2