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Author Details

Joseph A Ludwig
The University of Texas MD Anderson Cancer Center
2005
69
31
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36151848Retrospective evaluation of the role of gemcitabine-docetaxel in well-differentiated and dedifferentiated liposarcoma.Cancer Med2023
37745374Mapping the Single-cell Differentiation Landscape of Osteosarcoma.bioRxiv2023
37058010Impact of Biomarker-Matched Therapies on Outcomes in Patients with Sarcoma Enrolled in Early-Phase Clinical Trials (SAMBA 101).Clin Cancer Res2023
36288393Examining Stripes on a Herd of Zebras: Impact of Genomic Matching for Ultrarare Sarcomas in Phase 1 Clinical Trials (SAMBA 102).Clin Cancer Res2023
35228656Experimental models of undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumor.Lab Invest2022
35650195The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma.Nat Commun2022
35379887Multi-site desmoplastic small round cell tumors are genetically related and immune-cold.NPJ Precis Oncol2022
35582528Understanding sarcoma drug resistance one cell at a time.Cancer Drug Resist2022
35517059Commentary: A Special Edition in bone sarcoma.J Bone Oncol2022
36313661The immune landscape of undifferentiated pleomorphic sarcoma.Front Oncol2022
35128664Real-world use of palbociclib monotherapy in retroperitoneal liposarcomas at a large volume sarcoma center.Int J Cancer2022
35284040Correlation of nuclear pIGF-1R/IGF-1R and YAP/TAZ in a tissue microarray with outcomes in osteosarcoma patients.Oncotarget2022
35251924Targeting the IGF/PI3K/mTOR pathway and AXL/YAP1/TAZ pathways in primary bone cancer.J Bone Oncol2022
33408328Transcriptional activators YAP/TAZ and AXL orchestrate dedifferentiation, cell fate, and metastasis in human osteosarcoma.Cancer Gene Ther2021
33575859Outcomes of systemic therapy in metastatic phyllodes tumor of the breast.Breast Cancer Res Treat2021
32565716PET/CT Imaging as a Diagnostic Tool in Distinguishing Well-Differentiated versus Dedifferentiated Liposarcoma.Sarcoma2020
32057288Modeling the Tumor Microenvironment and Pathogenic Signaling in Bone Sarcoma.Tissue Eng Part B Rev2020
334632393D Tissue-Engineered Tumor Model for Ewing's Sarcoma That Incorporates Bone-like ECM and Mineralization.ACS Biomater Sci Eng2020
33050651Primary Ewing Sarcoma/Primitive Neuroectodermal Tumor of the Kidney: The MD Anderson Cancer Center Experience.Cancers (Basel)2020
32630797IGF-1R/mTOR Targeted Therapy for Ewing Sarcoma: A Meta-Analysis of Five IGF-1R-Related Trials Matched to Proteomic and Radiologic Predictive Biomarkers.Cancers (Basel)2020
30420447Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma.Clin Cancer Res2019
31542501Mechanically tunable coaxial electrospun models of YAP/TAZ mechanoresponse and IGF-1R activation in osteosarcoma.Acta Biomater2019
30733229Alpha Particle Radium 223 Dichloride in High-risk Osteosarcoma: A Phase I Dose Escalation Trial.Clin Cancer Res2019
29212731Clinical Activity of Pazopanib in Patients with Advanced Desmoplastic Small Round Cell Tumor.Oncologist2018
33418729Effects of Shear Stress Gradients on Ewing Sarcoma Cells Using 3D Printed Scaffolds and Flow Perfusion.ACS Biomater Sci Eng2018
29871905Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival.Clin Cancer Res2018
29383611Desmoplastic Small Round Cell Tumor Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Results of a Phase 2 Trial.Ann Surg Oncol2018
29626752Efficacy of ONC201 in Desmoplastic Small Round Cell Tumor.Neoplasia2018
27923328Modeling Stroma-Induced Drug Resistance in a Tissue-Engineered Tumor Model of Ewing Sarcoma.Tissue Eng Part A2017
28377484Phase Ib/II Study of the Safety and Efficacy of Combination Therapy with Multikinase VEGF Inhibitor Pazopanib and MEK Inhibitor Trametinib In Advanced Soft Tissue Sarcoma.Clin Cancer Res2017
29138631SARC006: Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated Chemotherapy-Naive Malignant Peripheral Nerve Sheath Tumors.Sarcoma2017
28710342Vincristine, Ifosfamide, and Doxorubicin for Initial Treatment of Ewing Sarcoma in Adults.Oncologist2017
26802024The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.Oncotarget2016
27882721Survival of patients with metastatic leiomyosarcoma: the MD Anderson Clinical Center for targeted therapy experience.Cancer Med2016
27748430Evaluation of Novel Targeted Therapies in Aggressive Biology Sarcoma Patients after progression from US FDA approved Therapies.Sci Rep2016
27486883Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials.Oncotarget2016
27576731IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma.J Natl Cancer Inst2016
25772182Prognostic factors and patterns of relapse in ewing sarcoma patients treated with chemotherapy and r0 resection.Int J Radiat Oncol Biol Phys2015
26240353Flow perfusion effects on three-dimensional culture and drug sensitivity of Ewing sarcoma.Proc Natl Acad Sci U S A2015
25869102Targeted therapies for advanced Ewing sarcoma family of tumors.Cancer Treat Rev2015
25964201An Oral Formulation of YK-4-279: Preclinical Efficacy and Acquired Resistance Patterns in Ewing Sarcoma.Mol Cancer Ther2015
24046124Complete cytoreduction and HIPEC improves survival in desmoplastic small round cell tumor.Ann Surg Oncol2014
25119929Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumors.PLoS One2014
251098533D tissue-engineered model of Ewing's sarcoma.Adv Drug Deliv Rev2014
24448245Universal marker and detection tool for human sarcoma circulating tumor cells.Cancer Res2014
23576741Modeling Ewing sarcoma tumors in vitro with 3D scaffolds.Proc Natl Acad Sci U S A2013
23477833Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial.Lancet Oncol2013
22492588Toxicity of hyperthermic intraperitoneal chemotherapy (HIPEC) in pediatric patients with sarcomatosis/carcinomatosis: early experience and phase 1 results.Pediatr Blood Cancer2012
23272660Extensive adipocytic maturation can be seen in myxoid liposarcomas treated with neoadjuvant doxorubicin and ifosfamide and pre-operative radiation therapy.Clin Sarcoma Res2012
22465830Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors.Clin Cancer Res2012
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Collaborators

Alexander J Lazar
The University of Texas MD Anderson Cancer Center
Co-authored papers 17
Najat C Daw
The University of Texas MD Anderson Cancer Center
Co-authored papers 11
Funda Meric-Bernstam
University of Texas MD Anderson Cancer Center
Co-authored papers 7
Jonathan C Trent
Sylvester Comprehensive Cancer Center, University of Miami
Co-authored papers 5
Kenneth R Hess
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
Raphael E Pollock
James Cancer Center, The Ohio State University
Co-authored papers 3
Richard Gorlick
University of Texas MD Anderson Cancer Center
Co-authored papers 3
John N Weinstein
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Jaume Mora
Pediatric Cancer Center Barcelona, Hospital Sant Joan de Deu
Co-authored papers 2
Waldemar Priebe
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Enrique de Alava
Servicio de Anatomia Patologica. Hospital Universitario Virgen del Rocio.
Co-authored papers 2
Lee J Helman
Osteosarcoma Institute
Co-authored papers 2
Phillip A Futreal
The University of Texas MD Anderson Cancer Center
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Jordi Rodon
The University of Texas MD Anderson Cancer Center
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Rebecca L Maywald
Baylor College of Medicine
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Keri Schadler
The University of Texas MD Anderson Cancer Center
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Takuro Nakamura
Tohoku University Graduate School of Medicine
Co-authored papers 1
E Alejandro Sweet-Cordero
University of California San Francisco
Co-authored papers 1
B. E. Snaar-Jagalska
Institute of Biology, Leiden University
Co-authored papers 1
Xingzhi Song
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Stefan Burdach
Technische Universitat Munchen
Co-authored papers 1
Abdul R Abdullah
Massachusetts General Hospital, and Harvard Medical School
Co-authored papers 1
Branka Radic-Sarikas
St. Anna Children's Cancer Research Institute (CCRI), Medical University of Vienna
Co-authored papers 1
Katia Scotlandi
IRCCS Istituto Ortopedico Rizzoli
Co-authored papers 1
Christian F Meyer
Johns Hopkins University School of Medicine
Co-authored papers 1
Markus Metzler
University Hospital Erlangen
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Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
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Stephen L Lessnick
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Release 1.2