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Author Details

Ghislain M C Bonamy
Prestige BioPharma Ltd
2004
27
19
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35238873Efficacy of HD201 vs Referent Trastuzumab in Patients With ERBB2-Positive Breast Cancer Treated in the Neoadjuvant Setting: A Multicenter Phase 3 Randomized Clinical Trial.JAMA Oncol2022
33536278NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models.Sci Transl Med2021
29341586Development of a Cytopathic Effect-Based Phenotypic Screening Assay against Cryptosporidium.ACS Infect Dis2018
29530849Imidazolopiperazines Kill both Rings and Dormant Rings in Wild-Type and K13 Artemisinin-Resistant Plasmodium falciparum In Vitro.Antimicrob Agents Chemother2018
28068668The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα.Nature2017
28216045Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit.Bioorg Med Chem Lett2017
28423309The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase.Cell Rep2017
29215331A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite <i>Plasmodium cynomolgi</i>.Elife2017
28731783Identification of SPPL2a Inhibitors by Multiparametric Analysis of a High-Content Ultra-High-Throughput Screen.SLAS Discov2017
28539634The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites.Sci Rep2017
28562588A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis.Nature2017
27642791UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes.Nat Microbiol2016
23300950FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.PLoS One2013
22423970Cofactors required for TLR7- and TLR9-dependent innate immune responses.Cell Host Microbe2012
22884261Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP.Chem Biol2012
22907892A small molecule promotes mitochondrial fusion in mammalian cells.Angew Chem Int Ed Engl2012
21866942A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor.ACS Chem Biol2011
22096101Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery.Science2011
20027183Human host factors required for influenza virus replication.Nature2010
20133616Determining the distribution of probes between different subcellular locations through automated unmixing of subcellular patterns.Proc Natl Acad Sci U S A2010
19365637LPA-induced mutually exclusive subcellular localization of active RhoA and Arp2 mRNA revealed by sequential FRET and FISH.Histochem Cell Biol2009
18641393Thyroid hormone receptor alpha1 follows a cooperative CRM1/calreticulin-mediated nuclear export pathway.J Biol Chem2008
18854154Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.Cell2008
17409357Receptor complexes cotransported via polarized endocytic pathways form clusters with distinct organizations.Mol Biol Cell2007
16741566Oncogenic conversion of the thyroid hormone receptor by altered nuclear transport.Nucl Recept Signal2006
15650025Cancer promoted by the oncoprotein v-ErbA may be due to subcellular mislocalization of nuclear receptors.Mol Endocrinol2005
14729678Nuclear export of the oncoprotein v-ErbA is mediated by acquisition of a viral nuclear export sequence.J Biol Chem2004
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Collaborators

Genomics Institute of the Novartis Research Foundation
Co-authored papers 5
Genomics Institute of the Novartis Research Foundation
Co-authored papers 4
Genomics Institute of the Novartis Research Foundation
Co-authored papers 4
The Scripps Research Institute
Co-authored papers 4
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
University of California San Diego
Co-authored papers 3
Paul-Ehrlich-Institut
Co-authored papers 2
University of California San Diego
Co-authored papers 2
Genomics Institute of the Novartis Research Foundation
Co-authored papers 2
Roche Pharma
Co-authored papers 2
Sanford-Burnham Medical Research Institute
Co-authored papers 2
United States Army Medical Research Institute of Infectious Diseases
Co-authored papers 2
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
a division of The Scripps Research Institute La Jolla
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Merck & Co., Inc.
Co-authored papers 1
university of california san diego School of Medicine
Co-authored papers 1
Co-authored papers 1
Institute of Molecular Genetics of the Czech Academy of Sciences
Co-authored papers 1
The Scripps Research Institute
Co-authored papers 1
Genomics Institute of the Novartis Research Foundation
Co-authored papers 1
The Salk Institute for Biological Studies
Co-authored papers 1
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
University of California irvine
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 1
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Co-authored papers 1
Merck & Co. Inc.
Co-authored papers 1