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Author Details

Brian D Crompton
2006
50
22
PMIDPaper TitleJournal TitlePublished Year
38096371Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML.Blood2024
36669140Randomized Phase III Trial of Ganitumab With Interval-Compressed Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing Sarcoma: A Report From the Children's Oncology Group.J Clin Oncol2023
37715723Phase 1 study of cabozantinib in combination with topotecan-cyclophosphamide for patients with relapsed Ewing sarcoma or osteosarcoma.2023
37956387Osteosarcoma Explorer: A Data Commons With Clinical, Genomic, Protein, and Tissue Imaging Data for Osteosarcoma Research.JCO Clin Cancer Inform2023
36780200Pilot Study of Recurrent Ewing's Sarcoma Management with Vigil/Temozolomide/Irinotecan and Assessment of Circulating Tumor (ct) DNA.2023
36592003Tumor biology, biomarkers, and liquid biopsy in pediatric renal tumors.Pediatr Blood Cancer2023
36996377Clinical Targeted Next-Generation Panel Sequencing Reveals <i>MYC</i> Amplification Is a Poor Prognostic Factor in Osteosarcoma.JCO Precis Oncol2023
37306107Phase 2 trial of palbociclib and ganitumab in patients with relapsed Ewing sarcoma.Cancer Med2023
36993649The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study.Res Sq2023
36724417Circulating Tumor DNA Is Prognostic in Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.J Clin Oncol2023
35325095Preclinical Modeling of Leiomyosarcoma Identifies Susceptibility to Transcriptional CDK Inhibitors through Antagonism of E2F-Driven Oncogenic Gene Expression.Clinical Cancer Research2022
35512711Germline predisposition to pediatric Ewing sarcoma is characterized by inherited pathogenic variants in DNA damage repair genes.Am J Hum Genet2022
35580298Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533.Journal of Clinical Oncology2022
36221002Adverse prognostic impact of the loss of STAG2 protein expression in patients with newly diagnosed localised Ewing sarcoma: A report from the Children's Oncology Group.Br J Cancer2022
35561344Circulating Tumor DNA Is Associated with Response and Survival in Patients with Advanced Leiomyosarcoma.Clinical Cancer Research2022
35809374Phase 2 study of anti-disialoganglioside antibody, dinutuximab, in combination with GM-CSF in patients with recurrent osteosarcoma: A report from the Children's Oncology Group.Eur J Cancer2022
35739269Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.Nat Med2022
35984457Serrated Polyposis Syndrome in a Young Adolescent Patient.J Pediatr Gastroenterol Nutr2022
36115869An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma.NPJ Precis Oncol2022
35347250Rapid and highly sensitive approach for multiplexed somatic fusion detection.Modern Pathology2022
34964003Germline Sequencing Improves Tumor-Only Sequencing Interpretation in a Precision Genomic Study of Patients With Pediatric Solid Tumor.JCO Precis Oncol2021
34129824STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma.Cancer Cell2021
33769463Patterns of Translocation Testing in Patients Enrolling in a Cooperative Group Trial for Newly Diagnosed Metastatic Ewing Sarcoma.Arch Pathol Lab Med2021
32667141Making the most of small samples: Optimization of tissue allocation of pediatric solid tumors for clinical and research use.Pediatric Blood and Cancer2020
32483734Using Liquid Biopsy in the Treatment of Patient with OS.Advances in Experimental Medicine and Biology2020
32598183Chasing ctDNA in Patients With Sarcoma.American Society of Clinical Oncology educational book / ASCO. American Society of Clinical Oncology. Meeting2020
30880335Correction: Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.Br J Cancer2019
30614191Assessment of circulating tumor DNA in pediatric solid tumors: The promise of liquid biopsies.Pediatric Blood and Cancer2019
30979745High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma.Clin Cancer Res2019
30860482Renal medullary carcinomas depend upon <i>SMARCB1</i> loss and are sensitive to proteasome inhibition.Elife2019
30793095Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease.JCO Precision Oncology2019
31392992EWS-FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex.Nucleic Acids Res2019
31355930Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group.Cancer2019
31240271Duality of purpose: Participant and parent understanding of the purpose of genomic tumor profiling research among children and young adults with solid tumors.JCO Precis Oncol2019
30131550Detection of circulating tumour DNA is associated with inferior outcomes in Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group.Br J Cancer2018
30027144Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors.JCO Precis Oncol2018
29997151Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.Mol Cancer Ther2018
29206863Blood collection in cell-stabilizing tubes does not impact germline DNA quality for pediatric patients.PLoS One2017
26822149Multicenter Feasibility Study of Tumor Molecular Profiling to Inform Therapeutic Decisions in Advanced Pediatric Solid Tumors: The Individualized Cancer Therapy (iCat) Study.JAMA Oncol2016
27429135Patient/parent perspectives on genomic tumor profiling of pediatric solid tumors: The Individualized Cancer Therapy (iCat) experience.Pediatr Blood Cancer2016
27329820Integrated genetic and pharmacologic interrogation of rare cancers.Nat Commun2016
27132463Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.Cancer Genet2016
26337082Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma.Oncotarget2015
26006721CSF 5-Methyltetrahydrofolate Serial Monitoring to Guide Treatment of Congenital Folate Malabsorption Due to Proton-Coupled Folate Transporter (PCFT) Deficiency.JIMD Reports2015
25186949The genomic landscape of pediatric Ewing sarcoma.Cancer Discov2014
25401475Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis.J Clin Invest2014
23536552High-throughput tyrosine kinase activity profiling identifies FAK as a candidate therapeutic target in Ewing sarcoma.Cancer Res2013
23770567Mutational heterogeneity in cancer and the search for new cancer-associated genes.Nature2013
19740703Reversible severe combined immunodeficiency phenotype secondary to a mutation of the proton-coupled folate transporter.Clinical Immunology2009
16123980Survival after recurrence of osteosarcoma: a 20-year experience at a single institution.Pediatric Blood and Cancer2006
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Broad Institute of the Massachusetts Institute of Technology and Harvard
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