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Author Details

John D Minna
University of Texas Southwestern Medical Center at Dallas
1967
902
163
PMIDPaper TitleJournal TitlePublished Year
38014454The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β-catenin signaling in lung cancer.Thorac Cancer2024
36647832Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer.J Clin Invest2023
37863065Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer.Cancer Cell2023
37985999IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells.Cell Commun Signal2023
37774698Loss of p53 and mutational heterogeneity drives immune resistance in an autochthonous mouse lung cancer model with high tumor mutational burden.Cancer Cell2023
37606995Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer.J Clin Invest2023
37600329Silencing of <i>GRHL2</i> induces epithelialâ¿¿toâ¿¿mesenchymal transition in lung cancer cell lines with different effects on proliferation and clonogenic growth.Oncol Lett2023
37255415A Comparative Study of Neuroendocrine Heterogeneity in Small Cell Lung Cancer and Neuroblastoma.Mol Cancer Res2023
37378310Dissecting molecular, pathological, and clinical features associated with tumor neural/neuroendocrine heterogeneity.iScience2023
37171983A comparative study of neuroendocrine heterogeneity in small cell lung cancer and neuroblastoma.Mol Cancer Res2023
37272226Single-cell transcriptomic analysis uncovers intratumoral heterogeneity and drug-tolerant persister in ALK-rearranged lung adenocarcinoma.Cancer Commun (Lond)2023
37035141Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers.Front Oncol2023
37398419ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers.bioRxiv2023
37327788MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma.Cancer Cell2023
37092555Tumor loss-of-function mutations in STK11/LKB1 induce cachexia.JCI Insight2023
37461694Deep Learning of Cell Spatial Organizations Identifies Clinically Relevant Insights in Tissue Images.Res Sq2023
36787696CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance.Cancer Cell2023
36812886Moving toward precision medicine with lung cancer organoids.Cell Rep Med2023
34654720Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado.Mol Cancer Res2022
35411116High-throughput functional evaluation of human cancer-associated mutations using base editors.Nat Biotechnol2022
35838183Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells.Cancer Commun (Lond)2022
35798240Tumor Cells Modulate Macrophage Phenotype in a Novel In Vitro Co-Culture Model of the NSCLC Tumor Microenvironment.J Thorac Oncol2022
35759731Longitudinal Analyses of COVID-19 Vaccination in Patients With Lung Cancer: Antibody Responses and Variant-Specific Neutralization.J Clin Oncol2022
35492873AXL targeting restores PD-1 blockade sensitivity of <i>STK11/LKB1</i> mutant NSCLC through expansion of TCF1<sup>+</sup> CD8 T cells.Cell Rep Med2022
35941179Author Correction: Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.Nat Commun2022
36090641Circulating mitochondrial DNA as a biomarker for lung cancer screening.Transl Lung Cancer Res2022
36325065Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation.iScience2022
35882862Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.Nat Commun2022
36386455Cellular senescence and lung cancer prognosis.Transl Lung Cancer Res2022
36077736A Pan-Cancer Assessment of <i>RB1</i>/<i>TP53</i> Co-Mutations.Cancers (Basel)2022
35288734Lung Cancer Cell of Origin: Controversy and Clinical Translational Implications.Cancer Res2022
35189561Unbiased peptoid cell screen identifies a peptoid targeting newly appeared cell surface vimentin on tumor transformed early lung cancer cells.Bioorg Med Chem2022
35149086Resistance to mutant KRAS<sup>V12</sup>-induced senescence in an hTERT/Cdk4-immortalized normal human bronchial epithelial cell line.Exp Cell Res2022
35134341AP-1 leads the way in lung cancer transformation.Dev Cell2022
34751162Lung Cancer Computational Biology and Resources.Cold Spring Harb Perspect Med2022
34774792Lung Cancer and Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Identifying Important Knowledge Gaps for Investigation.J Thorac Oncol2022
32577652Lung cancer models reveal SARS-CoV-2-induced EMT contributes to COVID-19 pathophysiology.bioRxiv2021
33495232Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis.Cancer Res2021
33547084Nsp1 protein of SARS-CoV-2 disrupts the mRNA export machinery to inhibit host gene expression.Sci Adv2021
33848475A rational targeted therapy for platinum-resistant small-cell lung cancer.Cancer Cell2021
33761321SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt.Dev Cell2021
33536620Elevated NSD3 histone methylation activity drives squamous cell lung cancer.Nature2021
33809063Single-Cell Expression Landscape of SARS-CoV-2 Receptor <i>ACE2</i> and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients.Cancers (Basel)2021
33750914Cell-autonomous immune gene expression is repressed in pulmonary neuroendocrine cells and small cell lung cancer.Commun Biol2021
34853306Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids.Nat Commun2021
34466783ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer.iScience2021
34430372Narrative review: molecular and genetic profiling of oligometastatic non-small cell lung cancer.Transl Lung Cancer Res2021
34752753Structure-based classification of EGFR mutations informs inhibitor selection for lung cancer therapy.Cancer Cell2021
34797899Phosphatidylserine receptors enhance SARS-CoV-2 infection.PLoS Pathog2021
34771509Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells.Cancers (Basel)2021
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Collaborators

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Co-authored papers 49
Guanghua Xiao
The University of Texas Southwestern Medical Center
Co-authored papers 25
Marion M Nau
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Co-authored papers 22
Lixia Diao
The University of Texas MD Anderson Cancer Center
Co-authored papers 22
Kevin R Coombes
Medical College of Georgia
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Michael A White
University of Georgia
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British Columbia Cancer Research Institute
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Ping Yang
Mayo Clinic
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Michael J Birrer
Co-authored papers 12
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Moores Cancer Center, university of california san diego
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Christopher I Amos
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Eugene R Zabarovsky
Co-authored papers 10
Roy S Herbst
Yale School of Medicine
Co-authored papers 10
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 10
Susan M Pinney
Co-authored papers 9
Hao Tang
Guizhou Medical University
Co-authored papers 9
Jonathan R Pollack
Stanford University School of Medicine
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Mariza de Andrade
Mayo Clinic
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Pierre P Massion
Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center
Co-authored papers 8
Daniela Seminara
National Cancer Institute, 9609 Medical Center Dr
Co-authored papers 8
Young H Kim
Stanford University
Co-authored papers 8
Yunyun Zhou
Children's Hospital of Philadelphia
Co-authored papers 7
Hyun Seok Kim
Seoul National University
Co-authored papers 7
Release 1.2