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Author Details
Full Name
Michael Grunstein
Affiliation
University of California los angeles
ORCID
Career Start Year
1969
Papers
120
H Index
70
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
30208392
Genetics, Biochemistry, and "Simple" Organisms Converge to Unlock Secrets in Histone Biology: The 2018 Albert Lasker Basic Medical Research Award.
JAMA
2018
25556180
Max Birnstiel 1933-2014: Gene pioneer.
Proc Natl Acad Sci U S A
2015
23798425
Acetylated histone H3K56 interacts with Oct4 to promote mouse embryonic stem cell pluripotency.
Proc Natl Acad Sci U S A
2013
23818500
Epigenetics in Saccharomyces cerevisiae.
Cold Spring Harb Perspect Biol
2013
22177115
The Rpd3 core complex is a chromatin stabilization module.
Curr Biol
2012
23124068
Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin.
Genes Dev
2012
22387026
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA.
Mol Cell
2012
21212735
γH2A is a component of yeast heterochromatin required for telomere elongation.
Cell Cycle
2011
21771901
Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast.
Proc Natl Acad Sci U S A
2011
22121899
Genome-wide mapping of histone modifications and mass spectrometry reveal H4 acetylation bias and H3K36 methylation at gene promoters in fission yeast.
Epigenomics
2010
19250903
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.
Mol Cell
2009
19666585
Histone H3 N-terminus regulates higher order structure of yeast heterochromatin.
Proc Natl Acad Sci U S A
2009
19570518
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.
Cell Stem Cell
2009
19266098
Dissecting nucleosome free regions by a segmental semi-Markov model.
PLoS One
2009
19061643
A ncRNA modulates histone modification and mRNA induction in the yeast GAL gene cluster.
Mol Cell
2008
18719283
Adenovirus small e1a alters global patterns of histone modification.
Science
2008
19023413
Cell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast.
PLoS Genet
2008
17446861
Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing.
EMBO J
2007
17889663
Sir2 deacetylates histone H3 lysine 56 to regulate telomeric heterochromatin structure in yeast.
Mol Cell
2007
17362198
Functions of site-specific histone acetylation and deacetylation.
Annu Rev Biochem
2007
16543223
Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast.
Genes Dev
2006
17052455
Histone H2B deacetylation at lysine 11 is required for yeast apoptosis induced by phosphorylation of H2B at serine 10.
Mol Cell
2006
16912715
Genome-wide patterns of histone modifications in yeast.
Nat Rev Mol Cell Biol
2006
15988529
Global histone modification patterns predict risk of prostate cancer recurrence.
Nature
2005
16286008
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.
Cell
2005
15882620
Acetylation in histone H3 globular domain regulates gene expression in yeast.
Cell
2005
16039595
Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dot1 and Set1.
Mol Cell
2005
16079916
Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast.
EMBO J
2005
14975313
Analysis of genome-wide histone acetylation state and enzyme binding using DNA microarrays.
Methods Enzymol
2004
16117649
Acetylation of yeast histone H4 lysine 16: a switch for protein interactions in heterochromatin and euchromatin.
Cold Spring Harb Symp Quant Biol
2004
15186774
Mapping global histone acetylation patterns to gene expression.
Cell
2004
12586729
Identification of a functional domain within the essential core of histone H3 that is required for telomeric and HM silencing in Saccharomyces cerevisiae.
Genetics
2003
12893178
In vivo protein-protein and protein-DNA crosslinking for genomewide binding microarray.
Methods
2003
12893177
Genomewide histone acetylation microarrays.
Methods
2003
14561399
Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3.
Curr Biol
2003
12671650
Histone acetylation and deacetylation in yeast.
Nat Rev Mol Cell Biol
2003
11714726
Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3.
J Biol Chem
2002
12379856
Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin.
Nat Genet
2002
12419235
Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region.
Mol Cell
2002
12453428
Histone acetylation regulates the time of replication origin firing.
Mol Cell
2002
12434058
Requirement of Hos2 histone deacetylase for gene activity in yeast.
Science
2002
12089521
Genome-wide binding map of the histone deacetylase Rpd3 in yeast.
Nat Genet
2002
12086601
Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases.
Cell
2002
12080091
Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast.
Genes Dev
2002
11867538
Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions.
EMBO J
2002
11172717
TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast.
Mol Cell
2001
11287668
HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.
Proc Natl Acad Sci U S A
2001
11545749
Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin.
Mol Cell
2001
11116189
25 years after the nucleosome model: chromatin modifications.
Trends Biochem Sci
2000
11100734
Global histone acetylation and deacetylation in yeast.
Nature
2000
1 - 50 of 120
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University of North Carolina
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University of Toronto
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