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Author Details

Michael Grunstein
University of California los angeles
1969
120
70
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
30208392Genetics, Biochemistry, and "Simple" Organisms Converge to Unlock Secrets in Histone Biology: The 2018 Albert Lasker Basic Medical Research Award.JAMA2018
25556180Max Birnstiel 1933-2014: Gene pioneer.Proc Natl Acad Sci U S A2015
23798425Acetylated histone H3K56 interacts with Oct4 to promote mouse embryonic stem cell pluripotency.Proc Natl Acad Sci U S A2013
23818500Epigenetics in Saccharomyces cerevisiae.Cold Spring Harb Perspect Biol2013
22177115The Rpd3 core complex is a chromatin stabilization module.Curr Biol2012
23124068Mechanism for epigenetic variegation of gene expression at yeast telomeric heterochromatin.Genes Dev2012
22387026Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA.Mol Cell2012
21212735γH2A is a component of yeast heterochromatin required for telomere elongation.Cell Cycle2011
21771901Topoisomerase II binds nucleosome-free DNA and acts redundantly with topoisomerase I to enhance recruitment of RNA Pol II in budding yeast.Proc Natl Acad Sci U S A2011
22121899Genome-wide mapping of histone modifications and mass spectrometry reveal H4 acetylation bias and H3K36 methylation at gene promoters in fission yeast.Epigenomics2010
19250903Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells.Mol Cell2009
19666585Histone H3 N-terminus regulates higher order structure of yeast heterochromatin.Proc Natl Acad Sci U S A2009
19570518Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures.Cell Stem Cell2009
19266098Dissecting nucleosome free regions by a segmental semi-Markov model.PLoS One2009
19061643A ncRNA modulates histone modification and mRNA induction in the yeast GAL gene cluster.Mol Cell2008
18719283Adenovirus small e1a alters global patterns of histone modification.Science2008
19023413Cell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast.PLoS Genet2008
17446861Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing.EMBO J2007
17889663Sir2 deacetylates histone H3 lysine 56 to regulate telomeric heterochromatin structure in yeast.Mol Cell2007
17362198Functions of site-specific histone acetylation and deacetylation.Annu Rev Biochem2007
16543223Acetylation of H2AZ Lys 14 is associated with genome-wide gene activity in yeast.Genes Dev2006
17052455Histone H2B deacetylation at lysine 11 is required for yeast apoptosis induced by phosphorylation of H2B at serine 10.Mol Cell2006
16912715Genome-wide patterns of histone modifications in yeast.Nat Rev Mol Cell Biol2006
15988529Global histone modification patterns predict risk of prostate cancer recurrence.Nature2005
16286008Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.Cell2005
15882620Acetylation in histone H3 globular domain regulates gene expression in yeast.Cell2005
16039595Histone H2B ubiquitylation controls processive methylation but not monomethylation by Dot1 and Set1.Mol Cell2005
16079916Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast.EMBO J2005
14975313Analysis of genome-wide histone acetylation state and enzyme binding using DNA microarrays.Methods Enzymol2004
16117649Acetylation of yeast histone H4 lysine 16: a switch for protein interactions in heterochromatin and euchromatin.Cold Spring Harb Symp Quant Biol2004
15186774Mapping global histone acetylation patterns to gene expression.Cell2004
12586729Identification of a functional domain within the essential core of histone H3 that is required for telomeric and HM silencing in Saccharomyces cerevisiae.Genetics2003
12893178In vivo protein-protein and protein-DNA crosslinking for genomewide binding microarray.Methods2003
12893177Genomewide histone acetylation microarrays.Methods2003
14561399Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3.Curr Biol2003
12671650Histone acetylation and deacetylation in yeast.Nat Rev Mol Cell Biol2003
11714726Acetylation of the yeast histone H4 N terminus regulates its binding to heterochromatin protein SIR3.J Biol Chem2002
12379856Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin.Nat Genet2002
12419235Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region.Mol Cell2002
12453428Histone acetylation regulates the time of replication origin firing.Mol Cell2002
12434058Requirement of Hos2 histone deacetylase for gene activity in yeast.Science2002
12089521Genome-wide binding map of the histone deacetylase Rpd3 in yeast.Nat Genet2002
12086601Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases.Cell2002
12080091Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast.Genes Dev2002
11867538Hyperacetylation of chromatin at the ADH2 promoter allows Adr1 to bind in repressed conditions.EMBO J2002
11172717TUP1 utilizes histone H3/H2B-specific HDA1 deacetylase to repress gene activity in yeast.Mol Cell2001
11287668HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.Proc Natl Acad Sci U S A2001
11545749Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin.Mol Cell2001
1111618925 years after the nucleosome model: chromatin modifications.Trends Biochem Sci2000
11100734Global histone acetylation and deacetylation in yeast.Nature2000
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Collaborators

David Geffen School of Medicine, University of California los angeles
Co-authored papers 12
L'Institut Suisse de Recherche Experimentale sur le Cancer (ISREC) Foundation
Co-authored papers 6
Co-authored papers 5
Karolinska Institute
Co-authored papers 3
The Rockefeller University
Co-authored papers 2
Tokyo University of Science
Co-authored papers 2
University of Pennsylvania
Co-authored papers 2
Center for Reproductive Science, University of California los angeles
Co-authored papers 2
University of California davis
Co-authored papers 1
Karolinska Institutet
Co-authored papers 1
Co-authored papers 1
University of Washington
Co-authored papers 1
University of North Carolina
Co-authored papers 1
Murdoch Children's Research Institute
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of Toronto
Co-authored papers 1
Baylor College of Medicine, USA Center for Precision Environmental Health
Co-authored papers 1
Wisconsin Institute for Discovery, University of Wisconsin-Madison
Co-authored papers 1
Karolinska Institutet, University College Sodertorn
Co-authored papers 1
Boston University School of Medicine, Boston University
Co-authored papers 1
The Scripps Research Institute
Co-authored papers 1
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University of Massachusetts Chan Medical School
Co-authored papers 1
Panum Institute, University of Copenhagen
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
College Street, University of Toronto
Co-authored papers 1
University of North Carolina at Chapel Hill
Co-authored papers 1
Princess Maxima Center for Pediatric Oncology
Co-authored papers 1
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1