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Author Details

Donald J Johann
Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences
1996
59
20
PMIDPaper TitleJournal TitlePublished Year
36251491BLOODPAC: Collaborating to chart a path towards blood-based screening for early cancer detection.Clin Transl Sci2023
38062992Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis.Exp Biol Med (Maywood)2023
36846293An advanced molecular medicine case report of a rare human tumor using genomics, pathomics, and radiomics.Front Genet2023
36828596Contrived Materials and a Data Set for the Evaluation of Liquid Biopsy Tests: A Blood Profiling Atlas in Cancer (BLOODPAC) Community Study.J Mol Diagn2023
35094324Microdissection Methods Utilizing Single-Cell Subtype Analysis and the Impact on Precision Medicine.Methods Mol Biol2022
35768876Deep oncopanel sequencing reveals within block position-dependent quality degradation in FFPE processed samples.Genome Biol2022
35418127Ultra-deep sequencing data from a liquid biopsy proficiency study demonstrating analytic validity.Sci Data2022
36129255Effect of Antigen Retrieval on Genomic DNA From Immunodissected Samples.J Histochem Cytochem2022
34659195Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed.Front Immunol2021
35475002Advancing NGS quality control to enable measurement of actionable mutations in circulating tumor DNA.Cell Rep Methods2021
33846644Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology.Nat Biotechnol2021
33863366A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency.Genome Biol2021
33863344Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions.Genome Biol2021
33929890BloodPAC Data Commons for Liquid Biopsy Data.JCO Clin Cancer Inform2021
35282311FDA-led consortium studies advance quality control of targeted next generation sequencing assays for precision oncology.Precis Cancer Med2021
35024310Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk.Acta Pharm Sin B2021
34647017NPARS-A Novel Approach to Address Accuracy and Reproducibility in Genomic Data Science.Front Big Data2021
32870995Generic Protocols for the Analytical Validation of Next-Generation Sequencing-Based ctDNA Assays: A Joint Consensus Recommendation of the BloodPAC's Analytical Variables Working Group.Clin Chem2020
32017048Minimum Technical Data Elements for Liquid Biopsy Data Submitted to Public Databases.Clin Pharmacol Ther2020
32777070Sustained fetal hematopoiesis causes juvenile death from leukemia: evidence from a dual-age-specific mouse model.Blood Adv2020
29344855Protocol for the Analysis of Laser Capture Microdissected Fresh-Frozen Tissue Homogenates by Silver-Stained 1D SDS-PAGE.Methods Mol Biol2018
29899869Direct molecular dissection of tumor parenchyma from tumor stroma in tumor xenograft using mass spectrometry-based glycoproteomics.Oncotarget2018
30622835Computer-Aided Laser Dissection: A Microdissection Workflow Leveraging Image Analysis Tools.J Pathol Inform2018
29405770Liquid biopsy and its role in an advanced clinical trial for lung cancer.Exp Biol Med (Maywood)2018
28808996Preparation and Immunoaffinity Depletion of Fresh Frozen Tissue Homogenates for Mass Spectrometry-Based Proteomics in the Context of Drug Target/Biomarker Discovery.Methods Mol Biol2017
25943786Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma.Blood2015
26424691Proceedings of the 2015 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference.BMC Bioinformatics2015
26424171Enhancing cancer clonality analysis with integrative genomics.BMC Bioinformatics2015
24497533Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease.Blood2014
25350881Leveraging the new with the old: providing a framework for the integration of historic microarray studies with next generation sequencing.BMC Bioinformatics2014
25350589Revealing the inherent heterogeneity of human malignancies by variant consensus strategies coupled with cancer clonal analysis.BMC Bioinformatics2014
24521024Mass spectrometry in cancer biomarker research: a case for immunodepletion of abundant blood-derived proteins from clinical tissue specimens.Biomark Med2014
24373936Patterns of central nervous system involvement in relapsed and refractory multiple myeloma.Clin Lymphoma Myeloma Leuk2014
23716540Metronomic therapy is an effective salvage treatment for heavily pre-treated relapsed/refractory multiple myeloma.Haematologica2013
24268045Towards the integration, annotation and association of historical microarray experiments with RNA-seq.BMC Bioinformatics2013
23603914Risk factors for MDS and acute leukemia following total therapy 2 and 3 for multiple myeloma.Blood2013
23625401Trypsin-mediated ¹⁸O/¹⁶O labeling for biomarker discovery.Methods Mol Biol2013
23625395Proteomic analysis of frozen tissue samples using laser capture microdissection.Methods Mol Biol2013
22214408Proteomic profiling of H-Ras-G12V induced hypertrophic cardiomyopathy in transgenic mice using comparative LC-MS analysis of thin fresh-frozen tissue sections.J Proteome Res2012
22665304Post-digestion ¹⁸O exchange/labeling for quantitative shotgun proteomics of membrane proteins.Methods Mol Biol2012
21761297Profiling solid tumor heterogeneity by LCM and biological MS of fresh-frozen tissue sections.Methods Mol Biol2011
20121140Combined blood/tissue analysis for cancer biomarker discovery: application to renal cell carcinoma.Anal Chem2010
20540505Optimized method for computing (18)O/(16)O ratios of differentially stable-isotope labeled peptides in the context of postdigestion (18)O exchange/labeling.Anal Chem2010
19284784Approaching solid tumor heterogeneity on a cellular basis by tissue proteomics using laser capture microdissection and biological mass spectrometry.J Proteome Res2009
19709643Optimization of protein solubilization for the analysis of the CD14 human monocyte membrane proteome using LC-MS/MS.J Proteomics2009
19083000Cancer and the tumor microenvironment: a review of an essential relationship.Cancer Chemother Pharmacol2009
18937426Quantitation of steroid hormones in thin fresh frozen tissue sections.Anal Chem2008
17489728Multiple biomarkers in molecular oncology.Expert Rev Mol Diagn2007
17892354Biomarker discovery: tissues versus fluids versus both.Expert Rev Mol Diagn2007
17409454Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival.Cancer Res2007
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Clinical Sequencing Division
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Oncology R&D
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University of Louisville
Co-authored papers 3
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Icahn School of Medicine at Mount Sinai
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