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Author Details
Full Name
Philip J Scarpace
Affiliation
University of Florida
ORCID
Career Start Year
1973
Papers
185
H Index
50
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
29089334
iBAT sympathetic innervation is not required for body weight loss induced by central leptin delivery.
Am J Physiol Endocrinol Metab
2018
30024775
Limiting feeding to the active phase reduces blood pressure without the necessity of caloric reduction or fat mass loss.
Am J Physiol Regul Integr Comp Physiol
2018
30006298
ACE2 activator diminazene aceturate reduces adiposity but preserves lean mass in young and old rats.
Exp Gerontol
2018
30246441
Oestradiol and leptin have separate but additive anorexigenic effects and differentially target fat mass in rats.
J Neuroendocrinol
2018
28419850
Overpressure blast injury-induced oxidative stress and neuroinflammation response in rat frontal cortex and cerebellum.
Behav Brain Res
2018
29131966
Activation of the central melanocortin system in rats persistently reduces body and fat mass independently of caloric reduction.
Can J Physiol Pharmacol
2018
28006433
Intracerebroventricular tempol administration in older rats reduces oxidative stress in the hypothalamus but does not change STAT3 signalling or SIRT1/AMPK pathway.
Appl Physiol Nutr Metab
2017
29044801
Differential physiological responses to central leptin overexpression in male and female rats.
J Neuroendocrinol
2017
28794174
Maternal Western diet age-specifically alters female offspring voluntary physical activity and dopamine- and leptin-related gene expression.
FASEB J
2017
28521325
Effect of High-Salt Diet on Age-Related High Blood Pressure and Hypothalamic Redox Signaling.
Pharmacology
2017
28051332
Activation of the central melanocortin system chronically reduces body mass without the necessity of long-term caloric restriction.
Can J Physiol Pharmacol
2017
25617379
Rapamycin Normalizes Serum Leptin by Alleviating Obesity and Reducing Leptin Synthesis in Aged Rats.
J Gerontol A Biol Sci Med Sci
2016
27298812
Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries.
J Exerc Nutrition Biochem
2016
27232670
Anorexic response to rapamycin does not appear to involve a central mechanism.
Clin Exp Pharmacol Physiol
2016
27226180
High dietary fructose does not exacerbate the detrimental consequences of high fat diet on basilar artery function.
J Physiol Pharmacol
2016
27040098
Protective effects of resveratrol on aging-induced cognitive impairment in rats.
Neurobiol Learn Mem
2016
27012992
Onset of leptin resistance shows temporal differences related to dose or pulsed treatment.
Eur J Pharmacol
2016
26855373
Fructose consumption does not worsen bone deficits resulting from high-fat feeding in young male rats.
Bone
2016
25617380
Rapamycin Versus Intermittent Feeding: Dissociable Effects on Physiological and Behavioral Outcomes When Initiated Early and Late in Life.
J Gerontol A Biol Sci Med Sci
2016
26104291
The functional and structural changes in the basilar artery due to overpressure blast injury.
J Cereb Blood Flow Metab
2015
26462882
Successful aging: Advancing the science of physical independence in older adults.
Ageing Res Rev
2015
24630519
The effects of enalapril and losartan on mechanical ventilation-induced sympathoadrenal activation and oxidative stress in rats.
J Surg Res
2014
24829407
Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia.
J Immunol
2014
24920667
Targeted leptin receptor blockade: role of ventral tegmental area and nucleus of the solitary tract leptin receptors in body weight homeostasis.
J Endocrinol
2014
24907295
The effects of aging on the functional and structural properties of the rat basilar artery.
Physiol Rep
2014
22982569
Leptin overexpression in VTA trans-activates the hypothalamus whereas prolonged leptin action in either region cross-desensitizes.
Neuropharmacology
2013
23570732
Overpressure blast-wave induced brain injury elevates oxidative stress in the hypothalamus and catecholamine biosynthesis in the rat adrenal medulla.
Neurosci Lett
2013
23493533
Dietary components in the development of leptin resistance.
Adv Nutr
2013
21636833
Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia.
J Gerontol A Biol Sci Med Sci
2012
22115947
Simultaneous introduction of a novel high fat diet and wheel running induces anorexia.
Physiol Behav
2012
20881371
The act of voluntary wheel running reverses dietary hyperphagia and increases leptin signaling in ventral tegmental area of aged obese rats.
Gerontology
2011
21551274
Effect of age on high-fat diet-induced hypertension.
Am J Physiol Heart Circ Physiol
2011
21565854
POMC overexpression in the ventral tegmental area ameliorates dietary obesity.
J Endocrinol
2011
21366729
Simultaneous POMC gene transfer to hypothalamus and brainstem increases physical activity, lipolysis and reduces adult-onset obesity.
Eur J Neurosci
2011
21418711
Prevention and reversal of diet-induced leptin resistance with a sugar-free diet despite high fat content.
Br J Nutr
2011
21059361
Region-specific diet-induced and leptin-induced cellular leptin resistance includes the ventral tegmental area in rats.
Neuropharmacology
2011
20034526
Intermittent MTII application evokes repeated anorexia and robust fat and weight loss.
Peptides
2010
20538045
Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity.
Neuroscience
2010
20193697
Wheel running eliminates high-fat preference and enhances leptin signaling in the ventral tegmental area.
Physiol Behav
2010
19277011
Nigrostriatal rAAV-mediated GDNF overexpression induces robust weight loss in a rat model of age-related obesity.
Mol Ther
2009
19679649
Responses to the cannabinoid receptor-1 antagonist, AM251, are more robust with age and with high-fat feeding.
J Endocrinol
2009
19726711
Central overexpression of leptin antagonist reduces wheel running and underscores importance of endogenous leptin receptor activity in energy homeostasis.
Am J Physiol Regul Integr Comp Physiol
2009
19713964
Effect of high-fat diet feeding on hypothalamic redox signaling and central blood pressure regulation.
Hypertens Res
2009
19422379
The soluble leptin receptor neutralizes leptin-mediated STAT3 signalling and anorexic responses in vivo.
Br J Pharmacol
2009
19091915
Leptin resistance: a prediposing factor for diet-induced obesity.
Am J Physiol Regul Integr Comp Physiol
2009
18086903
Synergy between leptin therapy and a seemingly negligible amount of voluntary wheel running prevents progression of dietary obesity in leptin-resistant rats.
Diabetes
2008
18703413
Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding.
Am J Physiol Regul Integr Comp Physiol
2008
18596107
Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity.
Am J Physiol Regul Integr Comp Physiol
2008
17082312
Leptin antagonist reveals an uncoupling between leptin receptor signal transducer and activator of transcription 3 signaling and metabolic responses with central leptin resistance.
J Pharmacol Exp Ther
2007
17984669
Leptin antagonist reverses hypertension caused by leptin overexpression, but fails to normalize obesity-related hypertension.
J Hypertens
2007
1 - 50 of 185
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Collaborators
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University of Florida
Co-authored papers
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Michael Matheny
American College of Medical Informatics, Department of Veteran Affairs, Harvard University T H Chan School of Public Health, Massachusetts Institute of Technology, The American Society for Clinical Investigation, University of Kentucky, Vanderbilt University Medical Center, Vanderbilt University Medical School
Co-authored papers
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Yi Zhang
Malcom Randall Veterans Affairs Medical Center
Co-authored papers
28
Christy S Carter
University of Alabama at Birmingham
Co-authored papers
19
Hale Z Toklu
College of Medicine, University of Central Florida
Co-authored papers
15
Nataliya Kirichenko
University of Florida
Co-authored papers
15
Drake Morgan
College of Medicine
Co-authored papers
14
Stephen E Borst
and Clinical Center
Co-authored papers
13
Kit-Yan Cheng
University of Florida
Co-authored papers
12
Sergei Zolotukhin
College of Medicine, University of Florida
Co-authored papers
11
Yasemin Kisbu-Sakarya
52979Koc University
Co-authored papers
11
Benedek Erdos
University of Vermont Larner College of Medicine
Co-authored papers
10
Victor Prima
College of Medicine, University of Florida
Co-authored papers
8
Gang Li
University of Florida College of Medicine
Co-authored papers
8
Alexandra Shapiro
University of Florida, College of Medicine
Co-authored papers
8
Jared T Wilsey
and Clinical Center, Department of Veterans Affairs Medical Center
Co-authored papers
7
Yongxin Gao
University of Florida College of Medicine
Co-authored papers
6
Kevin Y E Strehler
University of Florida College of Medicine
Co-authored papers
6
Christopher S Broxson
University of Florida Health System
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6
Eugene W Shek
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6
Bradley S Bender
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