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Author Details

Brad A Chapman
Harvard T.H. Chan School of Public Health
2003
45
26
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33797837Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.Alzheimers Dement2021
32193444Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data.Sci Rep2020
33173892Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.medRxiv2020
32998969Aβ-accelerated neurodegeneration caused by Alzheimer's-associated <i>ACE</i> variant R1279Q is rescued by angiotensin system inhibition in mice.Sci Transl Med2020
30858580Best practices for benchmarking germline small-variant calls in human genomes.Nat Biotechnol2019
30899106Author Correction: Best practices for benchmarking germline small-variant calls in human genomes.Nat Biotechnol2019
30210780The 2018 Bioinformatics Open Source Conference (GCCBOSC 2018).F1000Res2018
29967506Bioconda: sustainable and comprehensive software distribution for the life sciences.Nat Methods2018
29118973The 2017 Bioinformatics Open Source Conference (BOSC).F1000Res2017
28186563Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment.Hum Mol Genet2017
28392986Prioritisation of structural variant calls in cancer genomes.PeerJ2017
27060149VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.Nucleic Acids Res2016
27814745Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities.Breast Cancer Res2016
27781083The 2016 Bioinformatics Open Source Conference (BOSC).F1000Res2016
26914653The 2015 Bioinformatics Open Source Conference (BOSC 2015).PLoS Comput Biol2016
25024288The Bioinformatics Open Source Conference (BOSC) 2013.Bioinformatics2015
24531798Integrating human sequence data sets provides a resource of benchmark SNP and indel genotype calls.Nat Biotechnol2014
25472764Community-driven development for computational biology at Sprints, Hackathons and Codefests.BMC Bioinformatics2014
25296256Clonal dynamics of native haematopoiesis.Nature2014
24603872Comparison of illumina and 454 deep sequencing in participants failing raltegravir-based antiretroviral therapy.PLoS One2014
23364702Identification of small RNA pathway genes using patterns of phylogenetic conservation and divergence.Nature2013
23874191GEMINI: integrative exploration of genetic variation and genome annotations.PLoS Comput Biol2013
23596069Targeted exome sequencing of suspected mitochondrial disorders.Neurology2013
23398680The 3rd DBCLS BioHackathon: improving life science data integration with Semantic Web technologies.J Biomed Semantics2013
22121217The Stem Cell Discovery Engine: an integrated repository and analysis system for cancer stem cell comparisons.Nucleic Acids Res2012
23181507CloudMan as a platform for tool, data, and analysis distribution.BMC Bioinformatics2012
22700313Using cloud computing infrastructure with CloudBioLinux, CloudMan, and Galaxy.Curr Protoc Bioinformatics2012
22720264Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes.Cell Rep2012
22909249Bio.Phylo: a unified toolkit for processing, analyzing and visualizing phylogenetic trees in Biopython.BMC Bioinformatics2012
22281772Toward interoperable bioscience data.Nat Genet2012
22429538Cloud BioLinux: pre-configured and on-demand bioinformatics computing for the genomics community.BMC Bioinformatics2012
22143764The genomic binding sites of a noncoding RNA.Proc Natl Acad Sci U S A2011
22012622Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge.Genes Dev2011
20194119Pairwise selection assembly for sequence-independent construction of long-length DNA.Nucleic Acids Res2010
21168766Engineering enzyme specificity using computational design of a defined-sequence library.Chem Biol2010
21210983Galaxy CloudMan: delivering cloud compute clusters.BMC Bioinformatics2010
19304878Biopython: freely available Python tools for computational molecular biology and bioinformatics.Bioinformatics2009
16467140Buffering of crucial functions by paleologous duplicated genes may contribute cyclicality to angiosperm genome duplication.Proc Natl Acad Sci U S A2006
16979781Many gene and domain families have convergent fates following independent whole-genome duplication events in Arabidopsis, Oryza, Saccharomyces and Tetraodon.Trends Genet2006
15161969Ancient polyploidization predating divergence of the cereals, and its consequences for comparative genomics.Proc Natl Acad Sci U S A2004
14734308A comparative phylogenetic approach for dating whole genome duplication events.Bioinformatics2004
15081049Comparative genome analysis of monocots and dicots, toward characterization of angiosperm diversity.Curr Opin Biotechnol2004
12677405High resolution genetic mapping and candidate gene identification at the xa5 locus for bacterial blight resistance in rice ( Oryza sativa L.).Theor Appl Genet2003
12660784Unravelling angiosperm genome evolution by phylogenetic analysis of chromosomal duplication events.Nature2003
14638328Structure and evolution of cereal genomes.Curr Opin Genet Dev2003
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Collaborators

University of Melbourne
Co-authored papers 12
Harvard Medical School
Co-authored papers 9
James Hutton Institute
Co-authored papers 9
Co-authored papers 7
Lawrence Berkely National Laboratory, Massachusetts Institute of Technology, Princeton University
Co-authored papers 6
Duke University
Co-authored papers 5
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University of Illinois Urbana-Champaign
Co-authored papers 4
Johns Hopkins University
Co-authored papers 4
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Smurfit Institute of Genetics, Trinity College of Dublin
Co-authored papers 4
Johns Hopkins University
Co-authored papers 4
University of Colorado Anschutz Medical Campus
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Stanford University
Co-authored papers 3
Open Bioinformatics Foundation
Co-authored papers 3
National Institute of Standards and Technology
Co-authored papers 3
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Partners Healthcare Center for Personalized Genetic Medicine
Co-authored papers 2
Harvard T.H. Chan School of Public Health
Co-authored papers 2
Oxford e-Research Centre, University of Oxford
Co-authored papers 2
Database Center for Life Science
Co-authored papers 2
Center for Devices and Radiological Health
Co-authored papers 2
Novartis Pharma AG
Co-authored papers 2
Biodiversity Institute, University of Oxford
Co-authored papers 2
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Rothamsted Research Harpenden UK.
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Oncology R&D
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Stanford University School of Medicine
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