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Author Details

John Ziebuhr
Institute of Medical Virology Justus Liebig University
1995
111
48
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36549112Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors.Eur J Med Chem2023
37112819A Novel Insertion in the Hepatitis B Virus Surface Protein Leading to Hyperglycosylation Causes Diagnostic and Immune Escape.Viruses2023
37199624Conserved Characteristics of NMPylation Activities of Alpha- and Betacoronavirus NiRAN Domains.J Virol2023
35336926Rocaglates as Antivirals: Comparing the Effects on Viral Resistance, Anti-Coronaviral Activity, RNA-Clamping on eIF4A and Immune Cell Toxicity.Viruses2022
35534355Thapsigargin: key to new host-directed coronavirus antivirals?Trends Pharmacol Sci2022
35458456IFITM3 Interacts with the HBV/HDV Receptor NTCP and Modulates Virus Entry and Infection.Viruses2022
36376283Reply to: The stress-inducible ER chaperone GRP78/BiP is upregulated during SARS-CoV-2 infection and acts as a pro-viral protein.Nat Commun2022
35015105[Ten years of the National Reference Center for hepatitis B viruses and hepatitis D viruses in Giessen, Germany: activities and experiences].Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz2022
32930481Structure-Activity Relationships of Benzamides and Isoindolines Designed as SARS-CoV Protease Inhibitors Effective against SARS-CoV-2.ChemMedChem2021
33619526Reprograming of sRNA target specificity by the leader peptide peTrpL in response to antibiotic exposure.Nucleic Acids Res2021
33807988Targeting the DEAD-Box RNA Helicase eIF4A with Rocaglates-A Pan-Antiviral Strategy for Minimizing the Impact of Future RNA Virus Pandemics.Microorganisms2021
33774510Conflicting and ambiguous names of overlapping ORFs in the SARS-CoV-2 genome: A homology-based resolution.Virology2021
33658206Hallmarks of <i>Alpha-</i> and <i>Betacoronavirus</i> non-structural protein 7+8 complexes.Sci Adv2021
34850109Inhibition of SARS-CoV-2 coronavirus proliferation by designer antisense-circRNAs.Nucleic Acids Res2021
34545074Multi-level inhibition of coronavirus replication by chemical ER stress.Nat Commun2021
34108654SARS-CoV-2 Variants of Interest and Concern naming scheme conducive for global discourse.Nat Microbiol2021
33108263ICTV Virus Taxonomy Profile: <i>Roniviridae</i>.J Gen Virol2021
33422611The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo.Antiviral Res2021
33472860Coronavirus replication-transcription complex: Vital and selective NMPylation of a conserved site in nsp9 by the NiRAN-RdRp subunit.Proc Natl Acad Sci U S A2021
33237794Immunoglobulin deficiency as an indicator of disease severity in patients with COVID-19.Am J Physiol Lung Cell Mol Physiol2021
32266822Call for Papers: The Pathophysiology of COVID-19 and SARS-CoV-2 Infection.Am J Physiol Lung Cell Mol Physiol2020
31931103Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol.Antiviral Res2020
33024972Hallmarks of <i>Alpha</i>- and <i>Betacoronavirus</i> non-structural protein 7+8 complexes.bioRxiv2020
30993322Transcription attenuation-derived small RNA rnTrpL regulates tryptophan biosynthesis gene expression in trans.Nucleic Acids Res2019
31439691Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis.Genome Res2019
30918070Identification and Characterization of a Human Coronavirus 229E Nonstructural Protein 8-Associated RNA 3'-Terminal Adenylyltransferase Activity.J Virol2019
31078932Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.Virology2019
29167338Inhibition of Cytosolic Phospholipase A<sub>2</sub>α Impairs an Early Step of Coronavirus Replication in Cell Culture.J Virol2018
30014009A Single-Center Study of Viral Respiratory Tract Infections in Hospitalized Children From the Kurdistan Region of Iraq.Glob Pediatr Health2018
30065095Reverse Genetics for Type I Feline Coronavirus Field Isolate To Study the Molecular Pathogenesis of Feline Infectious Peritonitis.mBio2018
30058998Characterization of a bafinivirus exoribonuclease activity.J Gen Virol2018
29337162Antiviral activity of K22 against members of the order Nidovirales.Virus Res2018
29258862Broad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses.Antiviral Res2018
29223446Structural and functional conservation of cis-acting RNA elements in coronavirus 5'-terminal genome regions.Virology2018
28004945Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology.J Med Chem2017
28355270The NF-κB-dependent and -independent transcriptome and chromatin landscapes of human coronavirus 229E-infected cells.PLoS Pathog2017
28158275Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication.PLoS Pathog2017
28758629Identification and characterization of a Golgi retention signal in feline coronavirus accessory protein 7b.J Gen Virol2017
26973232Phylogenetic analysis of human influenza A/H3N2 viruses isolated in 2015 in Germany indicates significant genetic divergence from vaccine strains.Arch Virol2016
27712628The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.Adv Virus Res2016
27712629Preface.Adv Virus Res2016
27712622Coronavirus cis-Acting RNA Elements.Adv Virus Res2016
27345250Characterization of the 3rd International Standard for hepatitis B virus surface antigen (HBsAg).J Clin Virol2016
27405649Identification of specific residues in avian influenza A virus NS1 that enhance viral replication and pathogenicity in mammalian systems.J Gen Virol2016
26743314The PB1 segment of an influenza A virus H1N1 2009pdm isolate enhances the replication efficiency of specific influenza vaccine strains in cell culture and embryonated eggs.J Gen Virol2016
26854339Characterization of monoclonal antibodies against feline coronavirus accessory protein 7b.Vet Microbiol2016
26977900Proteolytic processing of mesonivirus replicase polyproteins by the viral 3C-like protease.J Gen Virol2016
25810542Influenza virus-induced caspase-dependent enlargement of nuclear pores promotes nuclear export of viral ribonucleoprotein complexes.J Virol2015
26338147Studies of nosocomial outbreaks of hepatitis B in nursing homes in Germany suggest a major role of hepatitis B e antigen expression in disease severity and progression.Int J Med Microbiol2015
26091504In Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses.Sci Rep2015
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Collaborators

Alexander E Gorbalenya
Leiden University Medical Center
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Christian Cambillau
Aix Marseille University and CNRS
Co-authored papers 3
Luis Enjuanes
Campus Universidad Autonoma de Madrid
Co-authored papers 2
Dmitri I Svergun
King's College London BHF Centre for Research Excellence
Co-authored papers 2
Ann Marie Egloff
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Co-authored papers 2
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Co-authored papers 1
Bette Korber
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Co-authored papers 1
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Wellcome Trust Sanger Institute
Co-authored papers 1
Michael S Diamond
Washington University School of Medicine
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Nankai University
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Institute of Nuclear Sciences VINCA
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Manolis Kellis
Massachusetts Institute of Technology
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International Renal Research Institute of Vicenza (IRRIV)
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University of California San Francisco
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The Institute of Medical Science, The University of Tokyo
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Noah Stern
Weizmann Institute of Science
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Giuliano Ciarimboli
University Hospital Munster
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Stephan Becker
Institute of Virology, Philipps University Marburg
Co-authored papers 1
Klaus Schughart
University of Tennessee Health Science Center
Co-authored papers 1
Chase W Nelson
Biodiversity Research Center, Taiwan Institute for Comparative Genomics
Co-authored papers 1
Irwin Jungreis
Broad Institute of MIT and Harvard
Co-authored papers 1
Andrew Rambaut
Institute of Ecology and Evolution, University of Edinburgh
Co-authored papers 1
Yaara Finkel
Weizmann Institute of Science
Co-authored papers 1
Ralph S Baric
University of North Carolina
Co-authored papers 1
Marion Koopmans
Erasmus Medical Center
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Andrew E Firth
University of Cambridge
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Duncan MacCannell
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Release 1.2