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Author Details

Bharat V Adkar
Harvard University
2007
12
10
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37094144Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase.Proc Natl Acad Sci U S A2023
34180142Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype.Mol Syst Biol2021
31097595Substrate inhibition imposes fitness penalty at high protein stability.Proc Natl Acad Sci U S A2019
29445020Trade-offs between microbial growth phases lead to frequency-dependent and non-transitive selection.Proc Biol Sci2018
29883608Accessibility of the Shine-Dalgarno Sequence Dictates N-Terminal Codon Bias in E. coli.Mol Cell2018
28812634Optimization of lag phase shapes the evolution of a bacterial enzyme.Nat Ecol Evol2017
27417136An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin.J Biol Chem2016
23667620Effect of signal peptide on stability and folding of Escherichia coli thioredoxin.PLoS One2013
22325784Protein model discrimination using mutational sensitivity derived from deep sequencing.Structure2012
20836529Role of water in the enzymatic catalysis: study of ATP + AMP â¿¿ 2ADP conversion by adenylate kinase.J Phys Chem A2011
21261390Dynamic coupling between the LID and NMP domain motions in the catalytic conversion of ATP and AMP to ADP by adenylate kinase.J Chem Phys2011
18069886Stereochemical criteria for prediction of the effects of proline mutations on protein stability.PLoS Comput Biol2007
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Collaborators

Eugene I Shakhnovich
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Co-authored papers 7
Raghavan Varadarajan
Indian Institute of Science
Co-authored papers 3
Purbani Chakrabarti
Babraham Institute
Co-authored papers 2
Kanika Bajaj
Genentech Inc.
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Mallur S Madhusudhan
Indian Institute of Science Education and Research Pune
Co-authored papers 1
Chandrasekaran Ramakrishnan
Indian Institute of Technology Madras
Co-authored papers 1
Orly Dym
Weizmann Institute of Science
Co-authored papers 1
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