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Author Details

Alex Sparreboom
Ohio State University
1994
382
86
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38071551Vincristine Disposition and Neurotoxicity Are Unchanged in Humanized CYP3A5 Mice.Drug Metab Dispos2024
36821823<i>DPYD</i> Testing: Time to Put Patient Safety First.J Clin Oncol2023
37908705Exploring pharmacokinetics of talazoparib in ABCB1/ABCG2-deficient mice using a novel UHPLC-MS/MS method.Heliyon2023
37792442Unique Cabozantinib Dosing Considerations in People Living with HIV and Cancer.Clin Cancer Res2023
37059009Determination and disposition of meta-iodobenzylguanidine in plasma and heart of transporter-deficient mice by UPLC-MS/MS.J Chromatogr B Analyt Technol Biomed Life Sci2023
37347545Targeting a xenobiotic transporter to ameliorate vincristine-induced sensory neuropathy.JCI Insight2023
37286564Author Correction: Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice.Nat Commun2023
37264059Increased renal elimination of endogenous and synthetic pyrimidine nucleosides in concentrative nucleoside transporter 1 deficient mice.Nat Commun2023
32761456Solute Carrier Transportome in Chemotherapy-Induced Adverse Drug Reactions.Rev Physiol Biochem Pharmacol2022
35546260Transporters and Toxicity: Insights From the International Transporter Consortium Workshop 4.Clin Pharmacol Ther2022
35456528Interaction of Antifungal Drugs with CYP3A- and OATP1B-Mediated Venetoclax Elimination.Pharmaceutics2022
36506732Targeting OCT2 with Duloxetine to Prevent Oxaliplatin-Induced Peripheral Neurotoxicity.Cancer Res Commun2022
36145680A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug-Drug Interaction Liabilities.Pharmaceutics2022
36068461Pharmacogenomics in Cytotoxic Chemotherapy of Cancer.Methods Mol Biol2022
36068460Pharmacogenomics in Targeted Therapy and Supportive Care Therapies for Cancer.Methods Mol Biol2022
35955741MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia.Int J Mol Sci2022
36296409Itraconazole-Induced Increases in Gilteritinib Exposure Are Mediated by CYP3A and OATP1B.Molecules2022
36054985Determination of the endogenous OATP1B biomarkers glycochenodeoxycholate-3-sulfate and chenodeoxycholate-24-glucuronide in human and mouse plasma by a validated UHPLC-MS/MS method.J Chromatogr B Analyt Technol Biomed Life Sci2022
35983889The role of OATP1B1 and OATP1B3 transporter polymorphisms in drug disposition and response to anticancer drugs: a review of the recent literature.Expert Opin Drug Metab Toxicol2022
34237188Contribution of membrane transporters to chemotherapy-induced cardiotoxicity.Basic Clin Pharmacol Toxicol2022
34117715Boosting the oral bioavailability of anticancer drugs through intentional drug-drug interactions.Basic Clin Pharmacol Toxicol2022
32905646DNA Methylation-Based Epigenetic Repression of SLC22A4 Promotes Resistance to Cytarabine in Acute Myeloid Leukemia.Clin Transl Sci2021
33495337Targeting OCT3 attenuates doxorubicin-induced cardiac injury.Proc Natl Acad Sci U S A2021
33684722Rapid quantification of vincristine in mouse plasma using ESI-LC-MS/MS: Application to pharmacokinetic studies.J Chromatogr B Analyt Technol Biomed Life Sci2021
33790797Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1.Front Pharmacol2021
33664059Regulation of OATP1B1 Function by Tyrosine Kinase-mediated Phosphorylation.Clin Cancer Res2021
34950932Intentional Modulation of Ibrutinib Pharmacokinetics through CYP3A Inhibition.Cancer Res Commun2021
34959286<i>In Vitro</i> and <i>In Vivo</i> Inhibition of MATE1 by Tyrosine Kinase Inhibitors.Pharmaceutics2021
34614509Gilteritinib-induced upregulation of S100A9 is mediated through BCL6 in acute myeloid leukemia.Blood Adv2021
34548319Precision Dosing of Targeted Therapies Is Ready for Prime Time.Clin Cancer Res2021
34518298Gilteritinib Inhibits Glutamine Uptake and Utilization in <i>FLT3</i>-ITD-Positive AML.Mol Cancer Ther2021
34576971Endogenous Biomarkers for SLC Transporter-Mediated Drug-Drug Interaction Evaluation.Molecules2021
34534550Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition.Kidney Int2021
33939491Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update.J Clin Oncol2021
34365291Development, validation, and application of an LC-MS/MS method for the determination of the AXL/FLT3 inhibitor gilteritinib in mouse plasma.J Chromatogr B Analyt Technol Biomed Life Sci2021
34205780Imaging-Based Characterization of a <i>Slco2b1<sup>(-/-)</sup></i> Mouse Model Using [<sup>11</sup>C]Erlotinib and [<sup>99m</sup>Tc]Mebrofenin as Probe Substrates.Pharmaceutics2021
33142018Role for Drug Transporters in Chemotherapy-Induced Peripheral Neuropathy.Clin Transl Sci2021
31350763Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1.Clin Pharmacol Ther2020
31924044Corrigendum to "Engineered multifunctional biodegradable hybrid microparticles for paclitaxel delivery in cancer therapy" [Mater Sci Eng C 102 (2019) 113-123].Mater Sci Eng C Mater Biol Appl2020
32916864Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors.Pharmaceutics2020
32825359Influence of Probenecid on the Pharmacokinetics and Pharmacodynamics of Sorafenib.Pharmaceutics2020
32989230Androgen receptor signalling impairs docetaxel efficacy in castration-resistant prostate cancer.Br J Cancer2020
32114507Role of Oatp2b1 in Drug Absorption and Drug-Drug Interactions.Drug Metab Dispos2020
32276560Role of <i>SLC</i> transporters in toxicity induced by anticancer drugs.Expert Opin Drug Metab Toxicol2020
32321718Intratumoral Comparison of Nanoparticle Entrapped Docetaxel (CPC634) with Conventional Docetaxel in Patients with Solid Tumors.Clin Cancer Res2020
32484793Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice.J Clin Invest2020
32534260Development and validation of a sensitive UHPLC-MS/MS analytical method for venetoclax in mouse plasma, and its application to pharmacokinetic studies.J Chromatogr B Analyt Technol Biomed Life Sci2020
32317630A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury.Nat Commun2020
31055183Development and validation of a UPLC-MS/MS analytical method for dofetilide in mouse plasma and urine, and its application to pharmacokinetic study.J Pharm Biomed Anal2019
31671477Predicting Paclitaxel Disposition in Humans With Whole-Body Physiologically-Based Pharmacokinetic Modeling.CPT Pharmacometrics Syst Pharmacol2019
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Collaborators

Sharyn D Baker
Ohio State University
Co-authored papers 78
Shuiying Hu
The Ohio State University
Co-authored papers 56
Alice A Gibson
The Ohio State University
Co-authored papers 35
Jason A Sprowl
School of Pharmacy and Pharmaceutical Sciences, University at Buffalo
Co-authored papers 20
Lie Li
Sino-French Hoffmann Institute, Guangzhou Medical University
Co-authored papers 12
Seth M Steinberg
Center for Cancer Research, National Cancer Institute
Co-authored papers 11
Navjotsingh Pabla
The Ohio State University
Co-authored papers 10
Ronald de Wit
Erasmus MC Cancer Institute
Co-authored papers 10
Giuliano Ciarimboli
University Hospital Munster
Co-authored papers 9
Howard L McLeod
Center for Precision Medicine and Functional Genomics, Utah Tech University
Co-authored papers 8
William E Evans
Departments of Oncology. St. Jude Children's Research Hospital
Co-authored papers 7
Guido Cavaletti
NeuroMI (Milan Center for Neuroscience)
Co-authored papers 7
Eberhard Schlatter
University Hospital Muenster
Co-authored papers 7
Guoqing Du
Second Affiliated Hospital of Harbin Medical University
Co-authored papers 7
Mary V Relling
Departments of Pharmaceutical Sciences.
Co-authored papers 6
Taosheng Chen
St. Jude Children's Research Hospital
Co-authored papers 6
Anne T Nies
and University of Tuebingen, University of Tuebingen
Co-authored papers 6
Su Sien Ong
St. Jude Children's Research Hospital
Co-authored papers 5
Michael A Carducci
Johns Hopkins School of Medicine
Co-authored papers 5
Matthias Schwab
and of Biochemistry and Pharmacy, University of Tuebingen
Co-authored papers 5
Aksana Vasilyeva
St Jude Children's Research Hospital
Co-authored papers 5
Ching-Hon Pui
St. Jude Children's Research Hospital
Co-authored papers 5
Antonio C Wolff
Co-authored papers 5
Jan H M Schellens
Department of Pharmaceutical Sciences, Utrecht University
Co-authored papers 4
Daelynn R Buelow
The Ohio State University
Co-authored papers 4
Roxann G Ingersoll
Mc-Kusick-Nathans Institute of Genetic Medicine, Johns Hopkins
Co-authored papers 3
Cheng Cheng
St. Jude Children's Research Hospital
Co-authored papers 3
Stanley Pounds
St. Jude Children's Research Hospital.
Co-authored papers 3
Kathleen M Giacomini
University of California San Francisco
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Lara E Sucheston-Campbell
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Release 1.2