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Author Details

Jake Chen
Tufts University School of Dental Medicine
2003
62
31
PMIDPaper TitleJournal TitlePublished Year
36703959Construction of ceRNA and m6A-related lncRNA networks associated with anti-inflammation of AdipoAI.Front Immunol2023
37928259A novel lncRNA-mediated epigenetic regulatory mechanism in periodontitis.Int J Biol Sci2023
37143319The adiponectin receptor agonist AdipoAI attenuates periodontitis in diabetic rats by inhibiting gingival fibroblast-induced macrophage migration.Br J Pharmacol2023
37092468AdipoAI suppresses osteoclastogenesis by activating AdipoR1/APPL1: An in vivo experimental study in diabetes-associated peri-implantitis.Clin Oral Implants Res2023
36873496AdipoRon accelerates bone repair of calvarial defect in diet-induced obesity mice.Heliyon2023
34984683A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes-associated periodontitis by enhancing autophagy in osteoclasts.J Periodontal Res2022
35813949The Periodontal Pathogen <i>Fusobacterium nucleatum</i> Exacerbates Alzheimer's Pathogenesis <i>via</i> Specific Pathways.Front Aging Neurosci2022
32986862Identification and characterization of a novel adiponectin receptor agonist adipo anti-inflammation agonist and its anti-inflammatory effects in vitro and in vivo.Br J Pharmacol2021
34650969Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis.Front Cell Dev Biol2021
34273868Osteogenic effects of microRNA-335-5p/lipidoid nanoparticles coated on titanium surface.Arch Oral Biol2021
341911256-Shogaol promotes bone resorption and accelerates orthodontic tooth movement through the JNK-NFATc1 signaling axis.J Bone Miner Metab2021
32572964Irisin deficiency disturbs bone metabolism.J Cell Physiol2021
31541471Potential roles of miR-335-5p on pathogenesis of experimental periodontitis.J Periodontal Res2020
31838062AdipoRon promotes diabetic fracture repair through endochondral ossification-based bone repair by enhancing survival and differentiation of chondrocytes.Exp Cell Res2020
30479003Central adiponectin induces trabecular bone mass partly through epigenetic downregulation of cannabinoid receptor CB1.J Cell Physiol2019
30626266An Adiponectin Receptor Agonist Reduces Type 2 Diabetic Periodontitis.J Dent Res2019
29377540MicroRNA-99a is a novel regulator of KDM6B-mediated osteogenic differentiation of BMSCs.J Cell Mol Med2018
29886386A novel Lipidoid-MicroRNA formulation promotes calvarial bone regeneration.Biomaterials2018
27064596Runx2/DICER/miRNA Pathway in Regulating Osteogenesis.J Cell Physiol2017
28944087Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism.Bone Res2017
28846804Overexpression of MiR-335-5p Promotes Bone Formation and Regeneration in Mice.J Bone Miner Res2017
27658728Bone Tissue Regeneration - Application of Mesenchymal Stem Cells and Cellular and Molecular Mechanisms.Curr Stem Cell Res Ther2017
26738448Cyclosporine A promotes cell proliferation, collagen and α-smooth muscle actin expressions in rat gingival fibroblasts by Smad3 activation and miR-29b suppression.J Periodontal Res2016
26399931Epigenetic Modulation in Periodontitis: Interaction of Adiponectin and JMJD3-IRF4 Axis in Macrophages.J Cell Physiol2016
25187480Adiponectin regulates bone marrow mesenchymal stem cell niche through a unique signal transduction pathway: an approach for treating bone disease in diabetes.Stem Cells2015
25923143Epigenetically Modified Bone Marrow Stromal Cells in Silk Scaffolds Promote Craniofacial Bone Repair and Wound Healing.Tissue Eng Part A2015
25389000Response to letter to the editor, "BET inhibitor JQ1 blocks inflammation and bone destruction".J Dent Res2015
24218084MicroRNA expression signature for Satb2-induced osteogenic differentiation in bone marrow stromal cells.Mol Cell Biochem2014
24780611Central adiponectin administration reveals new regulatory mechanisms of bone metabolism in mice.Am J Physiol Endocrinol Metab2014
24836538Adiponectin ameliorates experimental periodontitis in diet-induced obesity mice.PLoS One2014
22934794Association of CD14-260 polymorphisms, red-complex periodontopathogens and gingival crevicular fluid cytokine levels with cyclosporine A-induced gingival overgrowth in renal transplant patients.J Periodontal Res2013
24352891Transcription factor and bone marrow stromal cells in osseointegration of dental implants.Eur Cell Mater2013
22061107Sustained release of adiponectin improves osteogenesis around hydroxyapatite implants by suppressing osteoclast activity in ovariectomized rabbits.Acta Biomater2012
20658533Application of induced pluripotent stem (iPS) cells in periodontal tissue regeneration.J Cell Physiol2011
21862122Enhanced osseointegration of titanium implant through the local delivery of transcription factor SATB2.Biomaterials2011
21889205The use of injectable sonication-induced silk hydrogel for VEGF(165) and BMP-2 delivery for elevation of the maxillary sinus floor.Biomaterials2011
21385070Roles of SATB2 in osteogenic differentiation and bone regeneration.Tissue Eng Part A2011
21351149Effects of miR-335-5p in modulating osteogenic differentiation by specifically downregulating Wnt antagonist DKK1.J Bone Miner Res2011
21300805Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1.J Biol Chem2011
21492931Critical-size calvarial bone defects healing in a mouse model with silk scaffolds and SATB2-modified iPSCs.Biomaterials2011
18756497Targeted overexpression of BSP in osteoclasts promotes bone metastasis of breast cancer cells.J Cell Physiol2009
19828887Osterix enhances BMSC-associated osseointegration of implants.J Dent Res2009
19326395Applications of transgenics in studies of bone sialoprotein.J Cell Physiol2009
19505603Apatite-coated silk fibroin scaffolds to healing mandibular border defects in canines.Bone2009
19501905Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs.Biomaterials2009
18096892Phenotypic analysis of Dlx5 overexpression in post-natal bone.J Dent Res2008
18471237Expression of Osterix in mechanical stress-induced osteogenic differentiation of periodontal ligament cells in vitro.Eur J Oral Sci2008
18459139Haploinsufficiency of Runx2 results in bone formation decrease and different BSP expression pattern changes in two transgenic mouse models.J Cell Physiol2008
18597627Overexpression of bone sialoprotein leads to an uncoupling of bone formation and bone resorption in mice.J Bone Miner Res2008
17960569Systemically transplanted bone marrow stromal cells contributing to bone tissue regeneration.J Cell Physiol2008
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Collaborators

Jake Y Chen
Co-authored papers 62
Qisheng Tu
Tufts University School of Dental Medicine
Co-authored papers 48
Jin Zhang
Shandong University
Co-authored papers 23
Paloma Valverde
Co-authored papers 17
Dana Murray
Co-authored papers 12
Pishan Yang
Co-authored papers 11
Liming Yu
Co-authored papers 9
Lan Zhang
Co-authored papers 9
Yin Tang
Co-authored papers 8
Jean Tang
Co-authored papers 8
David L Kaplan
Co-authored papers 8
Shu Meng
Co-authored papers 7
Xiaofang Zhu
Co-authored papers 7
Thomas E Van Dyke
The Forsyth Institute
Co-authored papers 6
Qianqian Han
Co-authored papers 6
Lei Sui
Co-authored papers 6
Hongle Wu
Co-authored papers 6
Michel Dard
Co-authored papers 6
Jun Zhao
Co-authored papers 5
Youcheng Yu
Co-authored papers 5
En Luo
Co-authored papers 4
Gary S Stein
University of Vermont
Co-authored papers 4
Wenli Ma
Co-authored papers 4
Sung-Hoon Kim
Co-authored papers 4
Junxiang Lian
Co-authored papers 4
Jane B Lian
University of Vermont
Co-authored papers 4
Xingwen Wu
Co-authored papers 4
Hua Jiang
Co-authored papers 4
Leilei Zheng
Co-authored papers 4
Yuwei Wu
Co-authored papers 4
Release 1.2