Author details

Full Name

Zhen Chen

Affiliation

ORCID

Career Start Year

2009

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36913673	Epitranscriptional Regulation: From the Perspectives of Cardiovascular Bioengineering.	Annu Rev Biomed Eng	2023
36512424	Long noncoding RNA LEENE promotes angiogenesis and ischemic recovery in diabetes models.	J Clin Invest	2023
34806652	Role of endothelial cells in pulmonary fibrosis via SREBP2 activation.	JCI insight	2021
33644072	RAMP2-AS1 Regulates Endothelial Homeostasis and Aging.	Front Cell Dev Biol	2021
33542531	Publisher Correction: miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1.	Communications Biology	2021
33468662	Longitudinal shear stress response in human endothelial cells to atheroprone and atheroprotective conditions.	Proc Natl Acad Sci U S A	2021
34044251	On the modeling of mechanotransduction in flow-mediated dilation.		2021
34595164	Heme Oxygenase-1 at the Nexus of Endothelial Cell Fate Decision Under Oxidative Stress.	Front Cell Dev Biol	2021
33060583	Stress-induced RNA-chromatin interactions promote endothelial dysfunction.	Nat Commun	2020
31964851	Reply to Hartl and Gao: Lack of between-batch difference in the distributions of measured extracellular RNA levels.	Proc Natl Acad Sci U S A	2020
32393053	Suppression of Endothelial AGO1 Promotes Adipose Tissue Browning and Improves Metabolic Dysfunction.	Circulation	2020
32278310	Characterization of arterial flow mediated dilation via a physics-based model.		2020
32095737	Endothelial mechanobiology.	APL Bioengineering	2020
32747424	Integrative Omics Analyses Reveal Epigenetic Memory in Diabetic Renal Cells Regulating Genes Associated With Kidney Dysfunction.		2020
32788395	Reply to Verwilt et al.: Experimental evidence against DNA contamination in SILVER-seq.	Proc Natl Acad Sci U S A	2020
31320990	Differential gene expression and AKT targeting in triple negative breast cancer.	Oncotarget	2019
31597449	Extracellular MicroRNA-92a Mediates Endothelial Cell-Macrophage Communication.	Arterioscler Thromb Vasc Biol	2019
31762781	Brachial flow-mediated dilation by continuous monitoring of arterial cross-section with ultrasound imaging.	Ultrasound	2019
29742957	Abnormalities of vascular histology and collagen fiber configuration in patients with advanced chronic kidney disease.	Journal of Vascular Access	2019
30917677	Atheroprotective Flow Upregulates ITPR3 (Inositol 1,4,5-Trisphosphate Receptor 3) in Vascular Endothelium via KLF4 (KrÃ¼ppel-Like Factor 4)-Mediated Histone Modifications.	Arterioscler Thromb Vasc Biol	2019
30730019	Epigenetic Risk Profile of Diabetic Kidney Disease in High-Risk Populations.	Current Diabetes Reports	2019
30718424	Genome-wide colocalization of RNA-DNA interactions and fusion RNA pairs.	Proc Natl Acad Sci U S A	2019
31481608	Extracellular RNA in a single droplet of human serum reflects physiologic and disease states.	Proc Natl Acad Sci U S A	2019
29348663	Enhancer-associated long non-coding RNA LEENE regulates endothelial nitric oxide synthase and endothelial function.	Nat Commun	2018
30463374	Long Non-Coding RNA Modulation of VEGF-A during Hypoxia.	Non-coding RNA	2018
29570986	AMP-activated Protein Kinase Phosphorylation of Angiotensin-Converting Enzyme 2 in Endothelium Mitigates Pulmonary Hypertension.	American Journal of Respiratory and Critical Care Medicine	2018
27923814	miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition: Therapeutic Implications in Kawasaki Disease.	Circ Res	2017
28500253	LINC00341 exerts an anti-inflammatory effect on endothelial cells by repressing VCAM1.	Physiol Genomics	2017
28973892	Systems biology analysis of longitudinal functional response of endothelial cells to shear stress.	Proc Natl Acad Sci U S A	2017
28696247	MicroRNA-92a Mediates Endothelial Dysfunction in CKD.	J Am Soc Nephrol	2017
29255148	Tyrosine phosphatase SHP2 negatively regulates NLRP3 inflammasome activation via ANT1-dependent mitochondrial homeostasis.	Nature Communications	2017
28301736	Epigenetic Regulation: A New Frontier for Biomedical Engineers.	Annu Rev Biomed Eng	2017
27935860	T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice.	Oncotarget	2017
27965388	TIFA as a crucial mediator for NLRP3 inflammasome.	Proc Natl Acad Sci U S A	2016
26986624	Cardiovascular Protective Effect of Metformin and Telmisartan: Reduction of PARP1 Activity via the AMPK-PARP1 Cascade.	PLoS ONE	2016
25908724	A compendium on peripheral arterial disease.	Circulation Research	2015
25550450	Oxidative stress activates endothelial innate immunity via sterol regulatory element binding protein 2 (SREBP2) transactivation of microRNA-92a.	Circulation	2015
25188917	Endothelial dysfunction: the role of sterol regulatory element-binding protein-induced NOD-like receptor family pyrin domain-containing protein 3 inflammasome in atherosclerosis.	Current Opinion in Lipidology	2014
23727269	Mechanosensitive microRNAs-role in endothelial responses to shear stress and redox state.	Free Radic Biol Med	2013
23754392	Ca2+/calmodulin-dependent protein kinase kinase Î² phosphorylation of Sirtuin 1 in endothelium is atheroprotective.	Proc Natl Acad Sci U S A	2013
23838163	Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic-induced atherosclerosis susceptibility.	Circulation	2013
23878263	Shear stress activation of nuclear receptor PXR in endothelial detoxification.	Proc Natl Acad Sci U S A	2013
23477488	Regulation of SIRT1 by oxidative stress-responsive miRNAs and a systematic approach to identify its role in the endothelium.	Antioxidants and Redox Signaling	2013
23426184	Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis.	Journal of Clinical Investigation	2013
22454291	Glucagon regulates ACC activity in adipocytes through the CAMKKÎ²/AMPK pathway.	American Journal of Physiology - Endocrinology and Metabolism	2012
20479254	Shear stress, SIRT1, and vascular homeostasis.	Proc Natl Acad Sci U S A	2010
19131647	AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633.	Circulation Research	2009