Skip to Main Content

Author Details

Xiang Chen
St. Jude Children's Research Hospital
1999
70
42
PMIDPaper TitleJournal TitlePublished Year
36723810A Guide to MethylationToActivity: A Deep Learning Framework That Reveals Promoter Activity Landscapes from DNA Methylomes in Individual Tumors.Methods Mol Biol2023
37566049A Review of Single-Cell RNA-Seq Annotation, Integration, and Cell-Cell Communication.Cells2023
37414763Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma.Nat Commun2023
37257452Single-cell transcriptomics reveal a hyperacute cytokine and immune checkpoint axis after cardiac arrest in patients with poor neurological outcome.Med2023
36723810A Guide to MethylationToActivity: A Deep Learning Framework That Reveals Promoter Activity Landscapes from DNA Methylomes in Individual Tumors.Methods Mol Biol2023
37566049A Review of Single-Cell RNA-Seq Annotation, Integration, and Cell-Cell Communication.Cells2023
37257452Single-cell transcriptomics reveal a hyperacute cytokine and immune checkpoint axis after cardiac arrest in patients with poor neurological outcome.Med2023
37414763Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma.Nat Commun2023
35313970Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer.Genome Med2022
35590059Acute lymphoblastic leukemia displays a distinct highly methylated genome.Nat Cancer2022
36037042Identification and targeting of a HES1-YAP1-CDKN1C functional interaction in fusion-negative rhabdomyosarcoma.Mol Oncol2022
35483358The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma.Dev Cell2022
35857643Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.Sci Transl Med2022
35313970Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer.Genome Med2022
35857643Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma.Sci Transl Med2022
35590059Acute lymphoblastic leukemia displays a distinct highly methylated genome.Nat Cancer2022
35483358The myogenesis program drives clonal selection and drug resistance in rhabdomyosarcoma.Dev Cell2022
36037042Identification and targeting of a HES1-YAP1-CDKN1C functional interaction in fusion-negative rhabdomyosarcoma.Mol Oncol2022
33461601MethylationToActivity: a deep-learning framework that reveals promoter activity landscapes from DNA methylomes in individual tumors.Genome Biol2021
33461601MethylationToActivity: a deep-learning framework that reveals promoter activity landscapes from DNA methylomes in individual tumors.Genome Biol2021
34099548Accurate genomic variant detection in single cells with primary template-directed amplification.Proc Natl Acad Sci U S A2021
34315877Retinoblastoma from human stem cell-derived retinal organoids.Nat Commun2021
34099548Accurate genomic variant detection in single cells with primary template-directed amplification.Proc Natl Acad Sci U S A2021
34315877Retinoblastoma from human stem cell-derived retinal organoids.Nat Commun2021
32322368A comparison of methods accounting for batch effects in differential expression analysis of UMI count based single cell RNA sequencing.Comput Struct Biotechnol J2020
32322368A comparison of methods accounting for batch effects in differential expression analysis of UMI count based single cell RNA sequencing.Comput Struct Biotechnol J2020
31647544Molecular Mechanism of Telomere Length Dynamics and Its Prognostic Value in Pediatric Cancers.J Natl Cancer Inst2020
32060267MYCN amplification and ATRX mutations are incompatible in neuroblastoma.Nat Commun2020
31647544Molecular Mechanism of Telomere Length Dynamics and Its Prognostic Value in Pediatric Cancers.J Natl Cancer Inst2020
32060267MYCN amplification and ATRX mutations are incompatible in neuroblastoma.Nat Commun2020
30568299Metabolic heterogeneity underlies reciprocal fates of T<sub>H</sub>17 cell stemness and plasticity.Nature2019
31631027ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures.Cancer Cell2019
31566233Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data.Nucleic Acids Res2019
31862972Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor.Nat Commun2019
30395907Combinatorial screening using orthotopic patient derived xenograft-expanded early phase cultures of osteosarcoma identify novel therapeutic drug combinations.Cancer Lett2019
30568299Metabolic heterogeneity underlies reciprocal fates of T<sub>H</sub>17 cell stemness and plasticity.Nature2019
30651371The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment.Mol Cancer Res2019
31493975Nucleome Dynamics during Retinal Development.Neuron2019
30867008Analysis of error profiles in deep next-generation sequencing data.Genome Biol2019
31316100VCF2CNA: A tool for efficiently detecting copy-number alterations in VCF genotype data and tumor purity.Sci Rep2019
31862972Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor.Nat Commun2019
31493975Nucleome Dynamics during Retinal Development.Neuron2019
31316100VCF2CNA: A tool for efficiently detecting copy-number alterations in VCF genotype data and tumor purity.Sci Rep2019
31631027ATRX In-Frame Fusion Neuroblastoma Is Sensitive to EZH2 Inhibition via Modulation of Neuronal Gene Signatures.Cancer Cell2019
31566233Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data.Nucleic Acids Res2019
30867008Analysis of error profiles in deep next-generation sequencing data.Genome Biol2019
30651371The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment.Mol Cancer Res2019
30395907Combinatorial screening using orthotopic patient derived xenograft-expanded early phase cultures of osteosarcoma identify novel therapeutic drug combinations.Cancer Lett2019
29343754Development and validation of a brief diabetic foot ulceration risk checklist among diabetic patients: a multicenter longitudinal study in China.Sci Rep2018
29980617Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells.Sci Immunol2018
  • 1 - 50 of 140

Recommended Authors

Komal S Rathi
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Career Start Year 2014
Number of shared co-authors 14
Jiguang Wang
The Hong Kong University of Science and Technology
Career Start Year 2012
Number of shared co-authors 2
Krutika S Gaonkar
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Career Start Year 2012
Number of shared co-authors 6
Hiroko Tanaka
Tokyo Medical and Dental University
Career Start Year 2012
Number of shared co-authors 1
Alex Murison
Princess Margaret Cancer Centre, University Health Network
Career Start Year 2012
Number of shared co-authors 14
Chris Lawerenz
German Cancer Research Center (DKFZ)
Career Start Year 2011
Number of shared co-authors 9
Maxime Caron
Centre Hospitalier Universitaire Sainte-Justine
Career Start Year 2010
Number of shared co-authors 2
Natalie J??ger
Hopp Children's Cancer Center Heidelberg (KiTZ)
Career Start Year 2010
Number of shared co-authors 27
Adrian M Dubuc
Dana-Farber Cancer Institute
Career Start Year 2008
Number of shared co-authors 12
Xinmin Li
University of California los angeles
Career Start Year 2008
Number of shared co-authors 2
Ken Chen
University of Texas MD Anderson Cancer Center
Career Start Year 2007
Number of shared co-authors 24
Ritu Roy
University of California San Francisco.
Career Start Year 2007
Number of shared co-authors 1
Siyuan Zheng
Greehey Children's Cancer Research Institute
Career Start Year 2007
Number of shared co-authors 12
Linghua Wang
The University of Texas M. D. Anderson
Career Start Year 2006
Number of shared co-authors 6
Henry Yang
Cancer Science Institute of Singapore, National University of Singapore
Career Start Year 2005
Number of shared co-authors 1
Catrina Fronick
McDonnell Genome Institute, Washington University in St. Louis School of Medicine
Career Start Year 2004
Number of shared co-authors 10
Chip Stewart
Broad Institute of MIT and Harvard
Career Start Year 2004
Number of shared co-authors 16
Matthias Schlesner
University of Augsburg
Career Start Year 2004
Number of shared co-authors 14
Trevor J Pugh
Princess Margaret Cancer Centre, University Health Network
Career Start Year 2003
Number of shared co-authors 24
Jianmin Wang
Roswell Park Comprehensive Cancer Center
Career Start Year 2003
Number of shared co-authors 0
Jianhua Zhang
University of Texas MD Anderson Cancer Center
Career Start Year 2003
Number of shared co-authors 9
Peter Van Loo
The Francis Crick Institute
Career Start Year 2003
Number of shared co-authors 5
Olivier Elemento
Meyer Cancer Center
Career Start Year 2002
Number of shared co-authors 8
Jacqueline E Payton
Washington University School of Medicine.
Career Start Year 2001
Number of shared co-authors 16
Gad Getz
Broad Institute of the Massachusetts Institute of Technology and Harvard
Career Start Year 2000
Number of shared co-authors 26
Luciano G Martelotto
Monash University
Career Start Year 2000
Number of shared co-authors 0
Andrew J Gentles
Stanford Center for Biomedical Informatics Research, Stanford University
Career Start Year 1999
Number of shared co-authors 1
Robert L Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 3
Woong-Yang Park
Samsung Genome Institute, Samsung Medical Center
Career Start Year 1995
Number of shared co-authors 2
Javed Khan
Center for Cancer Research, National Cancer Institute
Career Start Year 1993
Number of shared co-authors 36

Collaborators

John Easton
St Jude Children's Research Hospital
Co-authored papers 40
Jinghui Zhang
Changhai Hospital, Second Military Medical University
Co-authored papers 37
Elaine R Mardis
The Ohio State University
Co-authored papers 25
Richard K Wilson
The Ohio State University
Co-authored papers 25
Michael Rusch
St Jude Children's Research Hospital
Co-authored papers 23
Michael N Edmonson
St. Jude Children's Research Hospital
Co-authored papers 18
Charles G Mullighan
St Jude Children's Research Hospital
Co-authored papers 17
Li Ding
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 16
Yongjin Li
Mayo Clinic
Co-authored papers 13
Charles Lu
Co-authored papers 13
Ching-Hon Pui
St. Jude Children's Research Hospital
Co-authored papers 13
Alberto S Pappo
St Jude Children's Research Hospital
Co-authored papers 12
David W Ellison
St. Jude Children's Research Hospital
Co-authored papers 12
Stanley Pounds
St. Jude Children's Research Hospital.
Co-authored papers 11
Xin Zhou
St. Jude Children's Research Hospital
Co-authored papers 11
Robert S Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 11
Xiaotu Ma
St. Jude Children's Research Hospital
Co-authored papers 11
Geoffrey Neale
St. Jude Children's Research Hospital
Co-authored papers 10
Robert Huether
Division of Clinical Genomics
Co-authored papers 10
Chunxu Qu
Co-authored papers 9
Lucinda Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 9
Stephen P Hunger
Children's Hospital of Philadelphia
Co-authored papers 8
Elizabeth Stewart
St Jude Children's Research Hospital
Co-authored papers 8
Mignon L Loh
University of Washington
Co-authored papers 7
Yu Liu
Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital
Co-authored papers 7
Kathryn G Roberts
St Jude Children's Research Hospital
Co-authored papers 7
Meenakshi Devidas
St Jude Children's Research Hospital
Co-authored papers 7
Anang A Shelat
St. Jude Children's Research Hospital
Co-authored papers 6
Suzanne J Baker
Co-authored papers 6
Daniela S Gerhard
National Cancer Institute
Co-authored papers 5
Release 1.2