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Author Details

Zolt??n N Oltvai
University of Rochester
1991
84
43
PMIDPaper TitleJournal TitlePublished Year
36455649Alterations in the omics profiles in mevalonate pathway-inhibited cancer cells.Life Sci2023
37628603Efficient Lung Cancer Molecular Diagnostics by Combining Next Generation Sequencing with Reflex Idylla Genefusion Assay Testing.Genes (Basel)2023
37517480Clinicopathologic and Molecular Characterization of Anorectal Neuroendocrine Carcinomas Reveals Human Papillomavirus, p53, and c-Myc as Alternative Mechanisms of Carcinogenesis.Mod Pathol2023
37541087HMG-CoA reductase degrader, SR-12813, counteracts statin-induced upregulation of HMG-CoA reductase and augments the anticancer effect of atorvastatin.Biochem Biophys Res Commun2023
37501994Expression of housekeeping genes varies depending on mevalonate pathway inhibition in cancer cells.Heliyon2023
37160316Clonal cytopenia of undetermined significance (CCUS)-associated reversion of donor-derived, transient αβ T-cell large granular clonal lymphocytosis, emerging post-transplant in a patient with a history of γδ T-cell large granular lymphocytic leukemia.Cold Spring Harb Mol Case Stud2023
35627184Utility of Select Gene Mutation Detection in Tumors by the Idylla Rapid Multiplex PCR Platform in Comparison to Next-Generation Sequencing.Genes (Basel)2022
35732498Incidental discovery of acute myeloid leukemia during liquid biopsy of a lung cancer patient.Cold Spring Harb Mol Case Stud2022
34140545Concomitant attenuation of HMGCR expression and activity enhances the growth inhibitory effect of atorvastatin on TGF-β-treated epithelial cancer cells.Sci Rep2021
33832922Assessing acquired resistance to IDH1 inhibitor therapy by full-exon <i>IDH1</i> sequencing and structural modeling.Cold Spring Harb Mol Case Stud2021
32532878Neonatal respiratory failure due to novel compound heterozygous mutations in the ABCA3 lipid transporter.Cold Spring Harb Mol Case Stud2020
32101277Rhapsody: predicting the pathogenicity of human missense variants.Bioinformatics2020
31127043Adjustment in tumbling rates improves bacterial chemotaxis on obstacle-laden terrains.Proc Natl Acad Sci U S A2019
29146185Biomarker identification for statin sensitivity of cancer cell lines.Biochem Biophys Res Commun2018
30034619Concomitant attenuation of HMG-CoA reductase expression potentiates the cancer cell growth-inhibitory effect of statins and expands their efficacy in tumor cells with epithelial characteristics.Oncotarget2018
29925909Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors.Sci Rep2018
30401978Statins attenuate outgrowth of breast cancer metastases.Br J Cancer2018
30458856Statin drugs to reduce breast cancer recurrence and mortality.Breast Cancer Res2018
29242632Quantitative assessment of cell fate decision between autophagy and apoptosis.Sci Rep2017
28993669Cell-cell communication enhances bacterial chemotaxis toward external attractants.Sci Rep2017
27484619Macromolecular crowding explains overflow metabolism in cells.Sci Rep2016
25192741BalestraWeb: efficient online evaluation of drug-target interactions.Bioinformatics2015
25175563Significance of p53 dynamics in regulating apoptosis in response to ionizing radiation, and polypharmacological strategies.Sci Rep2014
25534349Statin-induced mevalonate pathway inhibition attenuates the growth of mesenchymal-like cancer cells that lack functional E-cadherin mediated cell cohesion.Sci Rep2014
24157871Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells.Cell Death Dis2013
24289468Predicting drug-target interactions using probabilistic matrix factorization.J Chem Inf Model2013
24279929The metabolic demands of cancer cells are coupled to their size and protein synthesis rates.Cancer Metab2013
24330501Carbon catabolite repression correlates with the maintenance of near invariant molecular crowding in proliferating E. coli cells.BMC Syst Biol2013
22689770Matching experiments across species using expression values and textual information.Bioinformatics2012
23300522Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes.PLoS One2012
22976035Identification of motions in membrane proteins by elastic network models and their experimental validation.Methods Mol Biol2012
23078666Ongoing technological revolution. Preface.Clin Lab Med2012
23078662Workflow organization in pathology.Clin Lab Med2012
21559344Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology.PLoS One2011
22073143Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation.PLoS One2011
20080587Blueprint for antimicrobial hit discovery targeting metabolic networks.Proc Natl Acad Sci U S A2010
20702396Cross-species queries of large gene expression databases.Bioinformatics2010
20459610Catabolic efficiency of aerobic glycolysis: the Warburg effect revisited.BMC Syst Biol2010
20573514Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays.Bioorg Med Chem2010
19497118Computational disease modeling - fact or fiction?BMC Syst Biol2009
19376871Comparative genome-scale metabolic reconstruction and flux balance analysis of multiple Staphylococcus aureus genomes identify novel antimicrobial drug targets.J Bacteriol2009
18369434A semi-supervised method for predicting transcription factor-gene interactions in Escherichia coli.PLoS Comput Biol2008
18846199Impact of limited solvent capacity on metabolic rate, enzyme activities, and metabolite concentrations of S. cerevisiae glycolysis.PLoS Comput Biol2008
18599447The implications of human metabolic network topology for disease comorbidity.Proc Natl Acad Sci U S A2008
18215292Impact of the solvent capacity constraint on E. coli metabolism.BMC Syst Biol2008
17325675Shaping specificity in signaling networks.Nat Genet2007
17634615A pitfall in series of microarrays: the position of probes affects the cross-correlation of gene expression profiles.Methods Mol Biol2007
17652176Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity.Proc Natl Acad Sci U S A2007
16777593Exploring transcriptional regulatory networks in the worm.Cell2006
17069658Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae.BMC Bioinformatics2006
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Collaborators

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Co-authored papers 22
Carnegie Mellon University
Co-authored papers 7
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Laufer Center for Physical and Quantitative Biology, Stony Brook University
Co-authored papers 7
Co-authored papers 3
Winship Cancer Institute, Emory University
Co-authored papers 2
Janssen Research & Development Inc.
Co-authored papers 2
Carnegie Mellon University
Co-authored papers 1
King Abdullah University of Science and Technology (KAUST)
Co-authored papers 1
University of Vermont
Co-authored papers 1
University of Pittsburgh
Co-authored papers 1
Ecole Normale Superieure
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Linkoping University
Co-authored papers 1
Institute for Biomedical Engineering, University of Zurich & ETH Zurich
Co-authored papers 1
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Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS)
Co-authored papers 1
Hospital Clinic of Barcelona-Institut d'Investigacions
Co-authored papers 1
University of Miami
Co-authored papers 1
School of Molecular Sciences & College of Health Solutions, Arizona State University
Co-authored papers 1
European Institute for Systems Biology and Medicine
Co-authored papers 1
Washington University School of Medicine
Co-authored papers 1
Stanford University
Co-authored papers 1
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University of Florida
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
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