Author details

Full Name

Anna Waller

Affiliation

ORCID

Career Start Year

1998

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
33156327	TCRD and Pharos 2021: mining the human proteome for disease biology.	Nucleic Acids Res	2021
34086846	TIGA: target illumination GWAS analytics.	Bioinformatics	2021
31898878	How to Illuminate the Druggable Genome Using Pharos.	Curr Protoc Bioinformatics	2020
29232168	High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining.	SLAS Discovery	2018
29567993	Unexplored therapeutic opportunities in the human genome.	Nat Rev Drug Discov	2018
29177837	High-Throughput Flow Cytometry Screening of Multidrug Efflux Systems.	Methods Mol Biol	2018
29746793	High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL.	SLAS Discov	2018
29472638	Unexplored therapeutic opportunities in the human genome.	Nat Rev Drug Discov	2018
29746086	Activation of Rho Family GTPases by Small Molecules.	ACS Chem Biol	2018
27903890	Pharos: Collating protein information to shed light on the druggable genome.	Nucleic Acids Res	2017
28398460	TIN-X: target importance and novelty explorer.	Bioinformatics	2017
27641501	Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.	Cell	2016
26442911	Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.	J Biomol Screen	2016
26247207	A Pan-GTPase Inhibitor as a Molecular Probe.	PLoS ONE	2015
25378583	FRET detection of lymphocyte function-associated antigen-1 conformational extension.	Mol Biol Cell	2015
26558612	Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases.	PLoS One	2015
26503418	Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.	Nature Communications	2015
24441647	An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines.	J Biomol Screen	2014
25350399	An automated high-throughput cell-based multiplexed flow cytometry assay to identify novel compounds to target Candida albicans virulence-related proteins.	PLoS One	2014
23382385	Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.	J Biol Chem	2013
22923785	A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry.	J Biomol Screen	2013
23470221	Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.	Anal Biochem	2013
22260433	Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.	ACS Chem Biol	2012
22808084	A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6.	PLoS One	2012
22486388	A competitive nucleotide binding inhibitor: in vitro characterization of Rab7 GTPase inhibition.	ACS Chem Biol	2012
21720309	Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples.		2011
22368688	Drug Repurposing from an Academic Perspective.	Drug Discov Today Ther Strateg	2011
21515675	Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.	Journal of Biological Chemistry	2011
20018164	Identification of inhibitors of vacuolar proton-translocating ATPase pumps in yeast by high-throughput screening flow cytometry.	Analytical Biochemistry	2010
20008126	Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay.	Journal of Biomolecular Screening	2010
19754304	Conformational mAb as a tool for integrin ligand discovery.	Assay Drug Dev Technol	2009
19251697	Real-time analysis of conformation-sensitive antibody binding provides new insights into integrin conformational regulation.	J Biol Chem	2009
19470718	Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.	J Biomol Screen	2009
18534032	Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion.	BMC Immunology	2008
17513731	Regulation of cell adhesion by affinity and conformational unbending of alpha4beta1 integrin.	Journal of Immunology	2007
17854656	Some mechanistic insights into GPCR activation from detergent-solubilized ternary complexes on beads.		2007
16530386	Multiple receptor states are required to describe both kinetic binding and activation of neutrophils via N-formyl peptide receptor ligands.	Cellular Signalling	2006
16604533	Glutathione-S-transferase-green fluorescent protein fusion protein reveals slow dissociation from high site density beads and measures free GSH.	Cytometry. Part A : the journal of the International Society for Analytical Cytology	2006
15228359	An investigation of liquid carryover and sample residual for a high-throughput flow cytometer sample delivery system.	Analytical Chemistry	2004
15530645	Techniques: GPCR assembly, pharmacology and screening by flow cytometry.	Trends in Pharmacological Sciences	2004
15209517	Receptor binding kinetics and cellular responses of six N-formyl peptide agonists in human neutrophils.	Biochemistry	2004
14726530	Real-time analysis of ternary complex on particles: direct evidence for partial agonism at the agonist-receptor-G protein complex assembly step of signal transduction.	Journal of Biological Chemistry	2004
12769683	High throughput screening of G-protein coupled receptors via flow cytometry.	Combinatorial Chemistry and High Throughput Screening	2003
11590622	Validation of flow cytometric competitive binding protocols and characterization of fluorescently labeled ligands.	Cytometry	2001
9708989	Threshold and graded response behavior in human neutrophils: effect of varying G-protein or ligand concentrations.	Biochemistry	1998