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Author Details

Rachel L Graham
University of North Carolina
2004
61
37
PMIDPaper TitleJournal TitlePublished Year
36914616A live dengue virus vaccine carrying a chimeric envelope glycoprotein elicits dual DENV2-DENV4 serotype-specific immunity.Nat Commun2023
37193127Metatranscriptomics analysis reveals a novel transcriptional and translational landscape during Middle East respiratory syndrome coronavirus infection.iScience2023
370404391-<i>O</i>-Octadecyl-2-<i>O</i>-benzyl-<i>sn</i>-glyceryl-3-<i>phospho</i>-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity.J Med Chem2023
35862771A Multitrait Locus Regulates Sarbecovirus Pathogenesis.mBio2022
35677067A Multitrait Locus Regulates Sarbecovirus Pathogenesis.bioRxiv2022
33411764Novel modulators of p53-signaling encoded by unknown genes of emerging viruses.PLoS Pathog2021
34013261Common Mechanism of SARS-CoV and SARS-CoV-2 Pathogenesis across Species.bioRxiv2021
32253226An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.Sci Transl Med2020
31996437Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus.J Virol2020
31801868Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection.J Virol2020
33184236SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo.Science2020
33046644Swine acute diarrhea syndrome coronavirus replication in primary human cells reveals potential susceptibility to infection.Proc Natl Acad Sci U S A2020
32661400Author Correction: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.Nat Med2020
32899556Bile Facilitates Human Norovirus Interactions with Diverse Histoblood Group Antigens, Compensating for Capsid Microvariation Observed in 2016-2017 GII.2 Strains.Viruses2020
32587967Comparative analysis of coronavirus genomic RNA structure reveals conservation in SARS-like coronaviruses.bioRxiv2020
32668216Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice.Cell Rep2020
32392464SARS-CoV-2: Combating Coronavirus Emergence.Immunity2020
32390971The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses.Front Microbiol2020
32511392Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.bioRxiv2020
30355694Human Norovirus Epitope D Plasticity Allows Escape from Antibody Immunity without Loss of Capacity for Binding Cellular Ligands.J Virol2019
31233808Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase.Antiviral Res2019
30791623GII.4 Human Norovirus: Surveying the Antigenic Landscape.Viruses2019
29279138Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses.Virology2018
30013082A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques.Sci Rep2018
29976657Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines.J Virol2018
30393776Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform.Commun Biol2018
30380413Genetic Variation between Dengue Virus Type 4 Strains Impacts Human Antibody Binding and Neutralization.Cell Rep2018
29789360Bat Caliciviruses and Human Noroviruses Are Antigenically Similar and Have Overlapping Histo-Blood Group Antigen Binding Profiles.mBio2018
29435493Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion.mSphere2018
29511076Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.mBio2018
28659436Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.Sci Transl Med2017
28214731Jumping species-a mechanism for coronavirus persistence and survival.Curr Opin Virol2017
29152578Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis.mSphere2017
29073030Expanded subgenomic mRNA transcriptome and coding capacity of a nidovirus.Proc Natl Acad Sci U S A2017
28830941MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis.mBio2017
27050591Corrigendum: A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.Nat Med2016
26976607SARS-like WIV1-CoV poised for human emergence.Proc Natl Acad Sci U S A2016
26552008A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence.Nat Med2015
24253287Evaluation of serologic and antigenic relationships between middle eastern respiratory syndrome coronavirus and other coronaviruses to develop vaccine platforms for the rapid response to emerging coronaviruses.J Infect Dis2014
24778221Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution.Proc Natl Acad Sci U S A2014
24623413Coronavirus replicase-reporter fusions provide quantitative analysis of replication and replication complex formation.J Virol2014
24667706A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant.mBio2014
23631916Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus.mBio2013
24043791Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus.Proc Natl Acad Sci U S A2013
24217413A decade after SARS: strategies for controlling emerging coronaviruses.Nat Rev Microbiol2013
23142821A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease.Nat Med2012
21593585Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity.RNA Biol2011
19906932Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission.J Virol2010
20463816Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing.PLoS Pathog2010
17397959SARS coronavirus replicase proteins in pathogenesis.Virus Res2008
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Collaborators

University of North Carolina
Co-authored papers 56
Vanderbilt University Medical Center
Co-authored papers 24
University of North Carolina at Chapel Hill
Co-authored papers 21
The University of North Carolina at Chapel Hill
Co-authored papers 16
University of North Carolina at Chapel Hill
Co-authored papers 16
University of Texas Medical Branch
Co-authored papers 16
Co-authored papers 13
University of North Carolina at Chapel Hill
Co-authored papers 11
National Center for Toxicological Research
Co-authored papers 10
Co-authored papers 8
University of North Carolina at Chapel Hill
Co-authored papers 7
University of North Carolina at Chapel Hill.
Co-authored papers 6
Co-authored papers 4
and Lineberger Comprehensive Cancer Center, University of North Carolina System
Co-authored papers 4
Pacific Northwest National Laboratory
Co-authored papers 4
University of North Carolina
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Vanderbilt University Medical Center
Co-authored papers 3
University of North Carolina
Co-authored papers 3
Vanderbilt University Medical Center
Co-authored papers 3
University of North Carolina.
Co-authored papers 3
Pacific Northwest National Laboratory (PNNL)
Co-authored papers 3
University of North Carolina
Co-authored papers 3
The University of North Carolina at Chapel Hill
Co-authored papers 3
University of North Carolina
Co-authored papers 3
Washington University School of Medicine
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University of Maryland School of Medicine
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Marsico Lung Institute, University of North Carolina-Chapel Hill
Co-authored papers 2
Pacific Northwest National Laboratory
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