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Author Details

Justin M Watts
University of Miami, Sylvester Comprehensive Cancer Center
2014
59
19
PMIDPaper TitleJournal TitlePublished Year
36370742Olutasidenib alone or with azacitidine in IDH1-mutated acute myeloid leukaemia and myelodysplastic syndrome: phase 1 results of a phase 1/2 trial.Lancet Haematol2023
38066868The future paradigm of HMA + VEN or targeted inhibitor approaches: sequencing or triplet combinations in AML therapy.Hematology Am Soc Hematol Educ Program2023
37814121E7820, an anti-cancer sulfonamide, degrades RBM39 in patients with splicing factor mutant myeloid malignancies: a phase II clinical trial.Leukemia2023
37086447A phase 1b study of venetoclax and alvocidib in patients with relapsed/refractory acute myeloid leukemia.Hematol Oncol2023
37196640Olutasidenib: from bench to bedside.Blood Adv2023
36724515Olutasidenib (FT-2102) induces durable complete remissions in patients with relapsed or refractory IDH1-mutated AML.Blood Adv2023
36626250Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures.Blood2023
36741714The treatment of acute promyelocytic leukemia in 2023: Paradigm, advances, and future directions.Front Oncol2023
35096610<i>Post-hoc</i> Analysis of Pharmacodynamics and Single-Agent Activity of CD3xCD123 Bispecific Antibody APVO436 in Relapsed/Refractory AML and MDS Resistant to HMA or Venetoclax Plus HMA.Front Oncol2022
36467830Molecular characteristics and outcomes in Hispanic and non-Hispanic patients with acute myeloid leukemia.EJHaem2022
36338830The treatment of acute lymphoblastic leukemia in Jehovah's Witnesses and patients who cannot accept blood products.Leuk Res Rep2022
36107670Molecular annotation of extramedullary acute myeloid leukemia identifies high prevalence of targetable mutations.Cancer2022
35937938Profile of Glasdegib for the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML): Evidence to Date.Cancer Manag Res2022
35868306Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.Cancer Cell2022
36077629Functional Drug Screening of Small Molecule Inhibitors of Epigenetic Modifiers in Refractory AML Patients.Cancers (Basel)2022
34031004Outcomes of Adult Acute Myeloid Leukemia Treated With Gemtuzumab-Ozogamicin: Cue To Optimized Chemotherapy Backbone.Clin Lymphoma Myeloma Leuk2021
35822053CD123-Directed Bispecific Antibodies for Targeting MDS Clones and Immunosuppressive Myeloid-Derived Suppressor Cells (MDSC) in High-Risk Adult MDS Patients.Front Aging2021
33495312Clinical Responsiveness to All-trans Retinoic Acid Is Potentiated by LSD1 Inhibition and Associated with a Quiescent Transcriptome in Myeloid Malignancies.Clin Cancer Res2021
33483617Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML.Leukemia2021
33772143Outcomes of patients with IDH1-mutant relapsed or refractory acute myeloid leukemia receiving ivosidenib who proceeded to hematopoietic stem cell transplant.Leukemia2021
34439266A Clinical Phase 1B Study of the CD3xCD123 Bispecific Antibody APVO436 in Patients with Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome.Cancers (Basel)2021
34789825Correction to: Randomized phase 2 trial of pevonedistat plus azacitidine versus azacitidine for higher-risk MDS/CMML or low-blast AML.Leukemia2021
34771451Risk, Characteristics and Biomarkers of Cytokine Release Syndrome in Patients with Relapsed/Refractory AML or MDS Treated with CD3xCD123 Bispecific Antibody APVO436.Cancers (Basel)2021
34178531Emergent Radiotherapy for Leukemia-Induced Cranial Neuropathies Refractory to Intrathecal Therapy.Cureus2021
34172893Phase I First-in-Human Dose Escalation Study of the oral SF3B1 modulator H3B-8800 in myeloid neoplasms.Leukemia2021
31527168Development of 2 Bromodomain and Extraterminal Inhibitors With Distinct Pharmacokinetic and Pharmacodynamic Profiles for the Treatment of Advanced Malignancies.Clin Cancer Res2020
31841594Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia.Blood2020
33139625Advances in Acute Myeloid Leukemia: Recently Approved Therapies and Drugs in Development.Cancers (Basel)2020
32995351Discordance Between Radiologic Findings and Molecular Testing in Patients With Underlying Hematologic Malignancy and Coronavirus Disease 2019.Open Forum Infect Dis2020
32284317The Hi's and Lo's of Cytarabine in Acute Myeloid Leukemia.Clin Cancer Res2020
32477862Spontaneous remission of acute myeloid leukemia with NF1 alteration.Leuk Res Rep2020
32380538Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML.Blood Adv2020
30645972CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis.Cancer Cell2019
31888052A Phase 1B Clinical Study of Combretastatin A1 Diphosphate (OXi4503) and Cytarabine (ARA-C) in Combination (OXA) for Patients with Relapsed or Refractory Acute Myeloid Leukemia.Cancers (Basel)2019
31484534Correction to: Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia.J Transl Med2019
31061068Aurora Kinase A Inhibition Provides Clinical Benefit, Normalizes Megakaryocytes, and Reduces Bone Marrow Fibrosis in Patients with Myelofibrosis: A Phase I Trial.Clin Cancer Res2019
31109340Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia.J Transl Med2019
29192651Myeloid neoplasms with features intermediate between primary myelofibrosis and chronic myelomonocytic leukemia.Mod Pathol2018
30135719Recent advances in the understanding and treatment of acute myeloid leukemia.F1000Res2018
29920189Oncogenic TRK fusions are amenable to inhibition in hematologic malignancies.J Clin Invest2018
29894694CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis.Cancer Cell2018
30423301CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis.Cancer Cell2018
30267380Leveraging Hypomethylating Agents for Better MDS Therapy.Curr Hematol Malig Rep2018
30333627Functional genomic landscape of acute myeloid leukaemia.Nature2018
29175379Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study.Leuk Res2018
28575698Corrigendum to "KB004, a first in class monoclonal antibody targeting the receptor tyrosine kinase EphA3, in patients with advanced hematologic malignancies: Results from a phase 1 study" [Leuk. Res. 50 (Nov) (2016) 123-131. PubMed PMID: 27736729].Leuk Res2017
28157218Expanded safety analysis of pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukemia and myelodysplastic syndromes.Blood Cancer J2017
29093807Biological and clinical implications of telomere dysfunction in myeloid malignancies.Ther Adv Hematol2017
28784769Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies.Proc Natl Acad Sci U S A2017
28696354A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy.Int J Mol Sci2017
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Collaborators

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Co-authored papers 8
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College of Medicine, University of Florida
Co-authored papers 7
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University of Texas Southwestern Medical Center
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Co-authored papers 3
Harvard Stem Cell Institute, Harvard Medical School
Co-authored papers 3
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Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 3
Dana Farber Cancer Institute
Co-authored papers 3
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Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
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Knight Cancer Institute, Oregon Health & Science University
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St Jude Children's Research Hospital.
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Knight Cancer Institute, Oregon Health & Science University
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AbbVie Inc.
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Knight Cancer Institute, Oregon Health & Science University
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Assistance Publique des Hopitaux de Paris (AP-HP)
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College of Medicine, University of Florida
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