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Author Details
Full Name
Nicolas Rapin
Affiliation
Rigshospitalet, University of Copenhagen
ORCID
Career Start Year
2006
Papers
43
H Index
26
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
35545054
PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents.
Cell Rep
2022
34099695
Quantitative single-cell proteomics as a tool to characterize cellular hierarchies.
Nat Commun
2021
30635567
The splicing factor RBM25 controls MYC activity in acute myeloid leukemia.
Nat Commun
2019
31775043
ERG Controls B Cell Development by Promoting Igh V-to-DJ Recombination.
Cell Rep
2019
31623675
Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes.
Clin Epigenetics
2019
31309149
Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.
Sci Adv
2019
30395307
BloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profiles.
Nucleic Acids Res
2019
29695774
Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies.
Nat Commun
2018
30021172
Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment.
Cell Rep
2018
30015632
Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates.
J Clin Invest
2018
29986855
Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin.
Blood Adv
2018
29847803
Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors.
Cell Rep
2018
28263309
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.
Nat Med
2017
28126036
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.
Genome Biol
2017
27095194
Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality.
Nucleic Acids Res
2016
26507857
BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis.
Nucleic Acids Res
2016
27755585
MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis.
PLoS One
2016
28004750
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization.
Nat Commun
2016
25349154
TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.
Leukemia
2015
26385962
ERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation.
Genes Dev
2015
25886910
Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis.
Genes Dev
2015
25670329
Cellular origin of prognostic chromosomal aberrations in AML patients.
Leukemia
2015
24415956
C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors.
PLoS Genet
2014
24932908
Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML.
Oncogenesis
2014
24670763
An atlas of active enhancers across human cell types and tissues.
Nature
2014
24367003
Initiation of MLL-rearranged AML is dependent on C/EBPα.
J Exp Med
2014
24363398
Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.
Blood
2014
23143109
HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis.
Nucleic Acids Res
2013
23831605
Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors.
Exp Hematol
2013
23403033
Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries.
Genome Res
2013
22745298
HemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesis.
Blood
2012
23058041
Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug-drug interactions.
J Pharm Pharmacol
2012
21244330
CTLs' repertoire shaping in the thymus: a Monte Carlo simulation.
Autoimmunity
2011
21888970
Simulating kinetic parameters in transporter mediated permeability across Caco-2 cells. A case study of estrone-3-sulfate.
Eur J Pharm Sci
2011
21685045
Immune system simulation online.
Bioinformatics
2011
21112392
Gaboxadol has affinity for the proton-coupled amino acid transporter 1, SLC36A1 (hPAT1)--A modelling approach to determine IC(50) values of the three ionic species of gaboxadol.
Eur J Pharm Sci
2011
21244341
Bistability in autoimmune diseases.
Autoimmunity
2011
20419125
Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system.
PLoS One
2010
20439274
ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale.
Philos Trans A Math Phys Eng Sci
2010
20143317
The MHC motif viewer: a visualization tool for MHC binding motifs.
Curr Protoc Immunol
2010
19383844
ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization.
Brief Bioinform
2009
18766337
MHC motif viewer.
Immunogenetics
2008
19669470
Modelling the human immune system by combining bioinformatics and systems biology approaches.
J Biol Phys
2006
1 - 43 of 43
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Center for Genomic Medicine, Rigshospitalet Copenhagen University Hospital
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Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
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Technical University of Denmark
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The Netherlands Cancer Institute
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The Institute of Cancer Research
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2
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University of Copenhagen
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2
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Nikos Sidiropoulos
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2
Yun Chen
Hospital of Obstetrics and Gynecology, Fudan University
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Robin Andersson
University of Copenhagen
Co-authored papers
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David S Moss
Institute of Structural and Molecular Biology, University of London
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Statens Serum Institut
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Carsten O Daub
International Institute of Molecular and Cell Biology in Warsaw
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