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Author Details

Steven P Gygi
Harvard Medical School
1991
711
168
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38009700Adapting an Isobaric Tag-Labeled Yeast Peptide Standard to Develop Targeted Proteomics Assays.J Proteome Res2024
38009700Adapting an Isobaric Tag-Labeled Yeast Peptide Standard to Develop Targeted Proteomics Assays.J Proteome Res2024
37961719The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway.bioRxiv2024
37961719The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway.bioRxiv2024
36269172APC/CCdc20-mediated degradation of Clb4 prompts astral microtubule stabilization at anaphase onset.J Cell Biol2023
36269172APC/CCdc20-mediated degradation of Clb4 prompts astral microtubule stabilization at anaphase onset.J Cell Biol2023
37831546High-Level Secretion of Pregnancy Zone Protein Is a Novel Biomarker of DNA Damage-Induced Senescence and Promotes Spontaneous Senescence.J Proteome Res2023
37811788Deep Proteomic Compound Profiling with the Orbitrap Ascend Tribrid Mass Spectrometer Using Tandem Mass Tags and Real-Time Search.Anal Chem2023
37993712Structural insights into cytokine cleavage by inflammatory caspase-4.Nature2023
37722062Causal ALS genes impact the MHC class II antigen presentation pathway.Proc Natl Acad Sci U S A2023
37716347Metabolic modulation of mitochondrial mass during CD4<sup>+</sup> T cell activation.Cell Chem Biol2023
37980093Ran-Binding Protein 3 Phosphorylation Links the Ras and PI3-Kinase Pathways to Nucleocytoplasmic Transport.Mol Cell2023
37875116The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment.Dev Cell2023
37788668A disordered region controls cBAF activity via condensation and partner recruitment.Cell2023
38065956Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.Nat Commun2023
37962907Enhancing Proteome Coverage by Using Strong Anion-Exchange in Tandem with Basic-pH Reversed-Phase Chromatography for Sample Multiplexing-Based Proteomics.J Proteome Res2023
37873481Synaptic Activity Causes Minute-scale Changes in BAF Complex Composition and Function.bioRxiv2023
37873273Selective Mitochondrial Respiratory Complex I Subunit Deficiency Causes Tumor Immunogenicity.bioRxiv2023
37553386A conserved membrane curvature-generating protein is crucial for autophagosome formation in fission yeast.Nat Commun2023
37773750Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction.Cell Rep2023
37092553MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity.JCI Insight2023
37473754Liver mitochondrial cristae organizing protein MIC19 promotes energy expenditure and pedestrian locomotion by altering nucleotide metabolism.Cell Metab2023
36971515Enriching Cysteine-Containing Peptides Using a Sulfhydryl-Reactive Alkylating Reagent with a Phosphonic Acid Group and Immobilized Metal Affinity Chromatography.J Proteome Res2023
37405913Global and tissue-specific aging effects on murine proteomes.Cell Rep2023
37279271A specialized integrin-binding motif enables proTGF-β2 activation by integrin αVβ6 but not αVβ8.Proc Natl Acad Sci U S A2023
37277330Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas.Nat Commun2023
36712069Frontotemporal Dementia Patient Neurons With Progranulin Deficiency Display Protein Dyshomeostasis.bioRxiv2023
36712038RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1α.bioRxiv2023
37081311The relaxin receptor RXFP1 signals through a mechanism of autoinhibition.Nat Chem Biol2023
37267907Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α.Mol Cell2023
37019113The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia.Dev Cell2023
36818473After virus exposure, early bystander naïve CD8 T cell activation relies on NAD<sup>+</sup> salvage metabolism.Front Immunol2023
37014752SENP3 and USP7 regulate Polycomb-rixosome interactions and silencing functions.Cell Rep2023
36881002Driver Mutations Dictate the Immunologic Landscape and Response to Checkpoint Immunotherapy of Glioblastoma.Cancer Immunol Res2023
37453421Insulin sensitization by small molecules enhancing GLUT4 translocation.Cell Chem Biol2023
36944993Multi-omics analysis identifies drivers of protein phosphorylation.Genome Biol2023
37000627Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance.Cell Rep2023
36746962The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.Nat Commun2023
36681077Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues.Cell Metab2023
36921622Lactate regulates cell cycle by remodelling the anaphase promoting complex.Nature2023
36732331Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression.Nat Commun2023
37425825Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.bioRxiv2023
36919909Human Polo-like Kinase Inhibitors as Antiplasmodials.ACS Infect Dis2023
37162912Fission yeast CK1 promotes DNA double-strand break repair through both homologous recombination and non-homologous end joining.bioRxiv2023
37034684Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons.bioRxiv2023
36593396A proteome-wide atlas of drug mechanism of action.Nat Biotechnol2023
37962907Enhancing Proteome Coverage by Using Strong Anion-Exchange in Tandem with Basic-pH Reversed-Phase Chromatography for Sample Multiplexing-Based Proteomics.J Proteome Res2023
37716347Metabolic modulation of mitochondrial mass during CD4<sup>+</sup> T cell activation.Cell Chem Biol2023
37553386A conserved membrane curvature-generating protein is crucial for autophagosome formation in fission yeast.Nat Commun2023
38065956Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.Nat Commun2023
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Collaborators

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Judit Vill??n
University of Washington
Co-authored papers 44
Edward L Huttlin
Harvard Medical School
Co-authored papers 41
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Harvard Medical School
Co-authored papers 39
Bo Zhai
Co-authored papers 39
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Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 28
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Co-authored papers 22
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Cell Signaling Technology Inc.
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Stephen J Elledge
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Brigham and Women's Hospital
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Clinic for Swine, Ludwig-Maximilians-University
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IRIC - University of Montreal
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Harbin Medical University
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Konrad Hochedlinger
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Joseph D Mancias
Dana-Farber Cancer Institute
Co-authored papers 6
Soyeon Park
Co-authored papers 6
Robert A Obar
Harvard Medical School
Co-authored papers 5
Ailan Guo
College of Animal Medicine, Xinjiang Agricultural University
Co-authored papers 5
John Rogers
Co-authored papers 5
Clary B Clish
Broad Institute of MIT and Harvard
Co-authored papers 5
Alan D D'Andrea
Dana-Farber Cancer Institute
Co-authored papers 5
Michael J Comb
Co-authored papers 5
Hanno Steen
Boston Children's Hospital, USA Harvard Medical School, Harvard Medical School
Co-authored papers 5
Timothy J Griffin
University of Minnesota
Co-authored papers 5
Release 1.2