Author details

Full Name

Manuela Iezzi

Affiliation

ORCID

Career Start Year

1993

Papers

167

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37509383	The 2EF Antibody Targets a Unique N-Terminal Epitope of Trop-2 and Enhances the In Vivo Activity of the Cancer-Selective 2G10 Antibody.		2023
36831396	CAR-T-Derived Extracellular Vesicles: A Promising Development of CAR-T Anti-Tumor Therapy.		2023
36700398	Duality of Nrf2 in iron-overload cardiomyopathy.		2023
37308077	Pancreatic beta-cell specific BAG3 knockout results in chronic hyperinsulinemia inducing insulin resistance.		2023
37169737	p140Cap inhibits Î²-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response.		2023
36921314	3D-Informed Targeting of the Trop-2 Signal-Activation Site Drives Selective Cancer Vulnerability.		2023
35203439	Role of ADCC, CDC, and CDCC in Vaccine-Mediated Protection against Her2 Mammary Carcinogenesis.	Biomedicines	2022
36011047	HER2-Displaying M13 Bacteriophages induce Therapeutic Immunity against Breast Cancer.	Cancers	2022
34518653	Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis.	Cell Death Differ	2022
35267665	Blood Circulating CD133+ Extracellular Vesicles Predict Clinical Outcomes in Patients with Metastatic Colorectal Cancer.	Cancers	2022
35022194	Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer.	Journal for ImmunoTherapy of Cancer	2022
34359855	Prognostic Relevance of Neutrophil to Lymphocyte Ratio (NLR) in Luminal Breast Cancer: A Retrospective Analysis in the Neoadjuvant Setting.	Cells	2021
33749902	Resolvin D1 and D2 reduce SARS-CoV-2-induced inflammatory responses in cystic fibrosis macrophages.	FASEB Journal	2021
33845864	Resolvin D1 reduces cancer growth stimulating a protective neutrophil-dependent recruitment of anti-tumor monocytes.	Journal of Experimental and Clinical Cancer Research	2021
33674591	Deciphering the state of immune silence in fatal COVID-19 patients.	Nat Commun	2021
33445508	Enhanced Expression of in B Cells of CLL Improves the Anti-Tumor Cytotoxic T Cell Response.	Cancers	2021
33407599	Improvement of urinary tract symptoms and quality of life in benign prostate hyperplasia patients associated with consumption of a newly developed whole tomato-based food supplement: a phase II prospective, randomized double-blinded, placebo-controlled st	Journal of Translational Medicine	2021
34518197	Arginase 1-Based Immune Modulatory Vaccines Induce Anticancer Immunity and Synergize with Anti-PD-1 Checkpoint Blockade.	Cancer Immunology Research	2021
35173816	PANHER study: a 20-year treatment outcome analysis from a multicentre observational study of HER2-positive advanced breast cancer patients from the real-world setting.	Therapeutic Advances in Medical Oncology	2021
31330065	Distinct HR expression patterns significantly affect the clinical behavior of metastatic HER2+ breast cancer and degree of benefit from novel anti-HER2 agents in the real world setting.	International Journal of Cancer	2020
31900399	Repurposing a psychoactive drug for children with cancer: p27-dependent inhibition of metastatic neuroblastomas by Prozac.	Oncogenesis	2020
32528461	Resolvin D1 Reduces Lung Infection and Inflammation Activating Resolution in Cystic Fibrosis.	Frontiers in Immunology	2020
32809969	Baricitinib restrains the immune dysregulation in patients with severe COVID-19.	Journal of Clinical Investigation	2020
32521631	Development of a VLP-Based Vaccine Displaying an xCT Extracellular Domain for the Treatment of Metastatic Breast Cancer.	Cancers	2020
33076448	Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma.	Cancers	2020
33052054	Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia.	Arteriosclerosis, Thrombosis, and Vascular Biology	2020
32718996	Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem-Like Cells and Reduces Metastases through Effects on Lipid Anabolism.	Cancer Res	2020
31285546	The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.	Cell Death Differ	2020
31488891	Correction to: The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma.	Cell Death Differ	2020
31376137	Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment.	Cellular oncology (Dordrecht)	2019
30403909	A multicenter REtrospective observational study of first-line treatment with PERtuzumab, trastuzumab and taxanes for advanced HER2 positive breast cancer patients. RePer Study.	Cancer Biology and Therapy	2019
30536609	Palbociclib plus endocrine therapy in HER2 negative, hormonal receptor-positive, advanced breast cancer: A real-world experience.	Journal of Cellular Physiology	2019
30611095	Combination of peripheral neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio is predictive of pathological complete response after neoadjuvant chemotherapy in breast cancer patients.	Breast	2019
31492820	Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.	Cancer Res	2019
31280347	Weight loss and body mass index in advanced gastric cancer patients treated with second-line ramucirumab: a real-life multicentre study.	Journal of Cancer Research and Clinical Oncology	2019
31452691	Prognostic relevance of DNA damage and repair biomarkers in elderly patients with hormone-receptor-positive breast cancer treated with neoadjuvant hormone therapy: evidence from the real-world setting.	Therapeutic Advances in Medical Oncology	2019
31355032	A Case of Stage I Vulvar Squamous Cell Carcinoma with Early Relapse and Rapid Disease Progression.	Case Reports in Oncological Medicine	2019
31362705	PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes.	BMC Cancer	2019
29600801	Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries.	Nature Communications	2018
28422188	Resolvin D1 enhances the resolution of lung inflammation caused by long-term Pseudomonas aeruginosa infection.	Mucosal Immunology	2018
28710865	Neoadjuvant chemotherapy in triple-negative breast cancer: A multicentric retrospective observational study in real-life setting.	Journal of Cellular Physiology	2018
30408428	Investigational small molecules in phase II clinical trials for the treatment of epilepsy.	Expert Opinion on Investigational Drugs	2018
30545122	Effect of Gender on the Outcome of Patients Receiving Immune Checkpoint Inhibitors for Advanced Cancer: A Systematic Review and Meta-Analysis of Phase III Randomized Clinical Trials.	Journal of Clinical Medicine	2018
30050081	MiR-205-5p inhibition by locked nucleic acids impairs metastatic potential of breast cancer cells.	Cell Death and Disease	2018
30002426	Generation of multiparametric MRI maps by using Gd-labelled- RBCs reveals phenotypes and stages of murine prostate cancer.	Scientific Reports	2018
29906688	InÂ vitro and inÂ vivo studies of gold(I) azolate/phosphane complexes for the treatment of basal like breast cancer.	European Journal of Medicinal Chemistry	2018
30327365	Phage-Based Anti-HER2 Vaccination Can Circumvent Immune Tolerance against Breast Cancer.	Cancer Immunology Research	2018
30518925	Induction of immunosuppressive functions and NF-ÎºB by FLIP in monocytes.	Nat Commun	2018
29622580	Disruption of IFN-I Signaling Promotes HER2/Neu Tumor Progression and Breast Cancer Stem Cells.	Cancer Immunology Research	2018
29550398	EV20-mediated delivery of cytotoxic auristatin MMAF exhibits potent therapeutic efficacy in cutaneous melanoma.	Journal of Controlled Release	2018