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Author Details

Thomas P Zwaka
Icahn School of Medicine at Mount Sinai
2000
63
27
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36894709Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection.Nat Genet2023
37738970SARS-CoV-2 variants evolve convergent strategies to remodel the host response.Cell2023
37182209Regulatory architecture of housekeeping genes is driven by promoter assemblies.Cell Rep2023
36812912Bat pluripotent stem cells reveal unusual entanglement between host and viruses.Cell2023
35169796The oral drug nitazoxanide restricts SARS-CoV-2 infection and attenuates disease pathogenesis in Syrian hamsters.bioRxiv2022
35766385Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity.ACS Infect Dis2022
35150638Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission.Cell Host Microbe2022
34165550Ronin overexpression induces cerebellar degeneration in a mouse model of ataxia.Dis Model Mech2021
33495306Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A.Science2021
34515391Ronin governs the metabolic capacity of the embryonic lineage for post-implantation development.EMBO Rep2021
32707573Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.Nature2020
30358129FACS-Mediated Isolation of Neuronal Cell Populations From Virus-Infected Human Embryonic Stem Cell-Derived Cerebral Organoid Cultures.Curr Protoc Stem Cell Biol2019
31731178Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation.Stem Cell Res2019
29227831Generation of hiPSTZ16 (ISMMSi003-A) cell line from normal human foreskin fibroblasts.Stem Cell Res2018
29364887Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions.PLoS Genet2018
29435496Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain.mSystems2018
28579396THAP1: Role in Mouse Embryonic Stem Cell Survival and Differentiation.Stem Cell Reports2017
29117561Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs.Cell Rep2017
28950094Status Anxiety among Pluripotent Stem Cells?Dev Cell2017
28746313Stem cells: The cost of perpetual youth.Nature2017
28715716Ronin influences the DNA damage response in pluripotent stem cells.Stem Cell Res2017
26876175RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina.Cell Rep2016
26824388Single-cell analysis of transcription kinetics across the cell cycle.Elife2016
25576466New Editor-in-Chief.Stem Cell Res2015
26476785Editorial overview: Cell reprogramming, regeneration and repair: Reprogramming: the eternal circle.Curr Opin Genet Dev2015
26166574Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation.Cell Rep2015
25482987Wnt5a and Wnt11 inhibit the canonical Wnt pathway and promote cardiac progenitor development via the Caspase-dependent degradation of AKT.Dev Biol2015
24578347GCNF-dependent activation of cyclin D1 expression via repression of Mir302a during ESC differentiation.Stem Cells2014
23495137Epigenetic reprogramming of the germ cell nuclear factor gene is required for proper differentiation of induced pluripotent cells.Stem Cells2013
24262829Development: sketch for a theory of Oct4.Curr Biol2013
24030493Safeguards for cell cooperation in mouse embryogenesis shown by genome-wide cheater screen.Science2013
22389628p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells.PLoS Biol2012
23040470Pluripotency network in embryonic stem cells: maybe Leibniz was right all along.Cell Stem Cell2012
22770244The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells.Cell Stem Cell2012
22443931Pluripotency and nuclear reprogramming.Annu Rev Biochem2012
21561870Caspase-3 cleavage links delta-catenin to the novel nuclear protein ZIFCAT.J Biol Chem2011
22000107Blimp1 expression predicts embryonic stem cell development in vitro.Curr Biol2011
20048741Stem cell vaccination against cancer: fighting fire with fire?Mol Ther2010
21135244Unraveling the score of the enhancer symphony.Proc Natl Acad Sci U S A2010
21119690The stem cell "tunnel" effect.Mol Ther2010
20844526Stem cells: Troublesome memories.Nature2010
20581084Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells.Genes Dev2010
20038954Reduce, reuse, reprogram.Nat Methods2010
19896440Stem cells in 2009.Cell Stem Cell2009
18585351Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells.Cell2008
19022753Ronin and caspases in embryonic stem cells: a new perspective on regulation of the pluripotent state.Cold Spring Harb Symp Quant Biol2008
18564034H1 and H9 human embryonic stem cell lines are heterozygous for the ABO locus.Stem Cells Dev2008
18522852Caspase activity mediates the differentiation of embryonic stem cells.Cell Stem Cell2008
16730227Prognostic role of myocardial tumor necrosis factor-alpha and terminal complement complex expression in patients with dilated cardiomyopathy.Eur J Heart Fail2007
16399069Breathing chromatin in pluripotent stem cells.Dev Cell2006
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Collaborators

Icahn School of Medicine at Mount Sinai
Co-authored papers 23
Icahn School of Medicine at Mount Sinai
Co-authored papers 7
Co-authored papers 7
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 6
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Icahn School of Medicine at Mount Sinai
Co-authored papers 5
Icahn School of Medicine at Mount Sinai New York
Co-authored papers 4
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
University of California San Francisco
Co-authored papers 3
J. David Gladstone Institutes
Co-authored papers 3
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
The Scripps Research Institute
Co-authored papers 2
Co-authored papers 2
J. David Gladstone Institutes
Co-authored papers 2
J. David Gladstone Institutes
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
Texas Biomedical Research Institute
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
The First Affiliated Hospital of Soochow University
Co-authored papers 2
J. David Gladstone Institutes
Co-authored papers 2
The Gurdon Institute
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Rega Institute
Co-authored papers 2
Icahn School of Medicine at Mount Sinai
Co-authored papers 2
The Scripps Research Institute
Co-authored papers 2
Icahn School of Medicine at Mount Sinai
Co-authored papers 2