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Author Details
Full Name
Daria A Gaykalova
Affiliation
Institute for Genome Sciences, University of Maryland School of Medicine
ORCID
Career Start Year
2006
Papers
57
H Index
25
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37674725
Identification of CT-based non-invasive Radiographic Biomarkers for Overall Survival Stratification in Oral Cavity Squamous Cell Carcinoma.
Res Sq
2023
37662332
Insights into the Mechanisms and Structure of Breakage-Fusion-Bridge Cycles in Cervical Cancer using Long-Read Sequencing.
medRxiv
2023
35201318
Entinostat Decreases Immune Suppression to Promote Antitumor Responses in a HER2+ Breast Tumor Microenvironment.
Cancer Immunol Res
2022
35667295
Simultaneously targeting ErbB family kinases and PI3K in HPV-positive head and neck squamous cell carcinoma.
Oral Oncol
2022
35571032
Epigenetic Regulations of Perineural Invasion in Head and Neck Squamous Cell Carcinoma.
Front Genet
2022
35016036
The use of machine learning to discover regulatory networks controlling biological systems.
Mol Cell
2022
34589558
Correction: Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor.
Oncoscience
2021
32164487
Chromatin structure regulates cancer-specific alternative splicing events in primary HPV-related oropharyngeal squamous cell carcinoma.
Epigenetics
2020
31830557
Somatic mitochondrial mutation discovery using ultra-deep sequencing of the mitochondrial genome reveals spatial tumor heterogeneity in head and neck squamous cell carcinoma.
Cancer Lett
2020
33015029
Extracellular Vesicles Released by Tumor Endothelial Cells Spread Immunosuppressive and Transforming Signals Through Various Recipient Cells.
Front Cell Dev Biol
2020
32848210
HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers.
Oncogene
2020
32694696
Correction: Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines.
Br J Cancer
2020
32392348
Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets.
Nucleic Acids Res
2020
32362655
Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines.
Br J Cancer
2020
32401780
Correction: Novel Insight into Mutational Landscape of Head and Neck Squamous Cell Carcinoma.
PLoS One
2020
31002670
CancerInSilico: An R/Bioconductor package for combining mathematical and statistical modeling to simulate time course bulk and single cell gene expression data in cancer.
PLoS Comput Biol
2019
31636280
Differentially Methylated Super-Enhancers Regulate Target Gene Expression in Human Cancer.
Sci Rep
2019
31097695
Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.
Nat Commun
2019
31142745
Publisher Correction: Chromatin dysregulation and DNA methylation at transcription start sites associated with transcriptional repression in cancers.
Nat Commun
2019
29342249
Splice Expression Variation Analysis (SEVA) for inter-tumor heterogeneity of gene isoform usage in cancer.
Bioinformatics
2018
29909892
HEY1 is expressed independent of NOTCH1 and is associated with poor prognosis in head and neck squamous cell carcinoma.
Oral Oncol
2018
30070359
Discovery and development of differentially methylated regions in human papillomavirus-related oropharyngeal squamous cell carcinoma.
Int J Cancer
2018
30118659
Functional characterization of alternatively spliced GSN in head and neck squamous cell carcinoma.
Transl Res
2018
30514962
PDGF enhances the protective effect of adipose stem cell-derived extracellular vesicles in a model of acute hindlimb ischemia.
Sci Rep
2018
30341436
Structural interpretation of DNA-protein hydroxyl-radical footprinting experiments with high resolution using HYDROID.
Nat Protoc
2018
29792227
Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance.
Genome Med
2018
29556515
Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor.
Oncoscience
2018
28968850
Epigenetic regulation of gene expression in cancer: techniques, resources and analysis.
Brief Funct Genomics
2018
28733453
A Novel Functional Splice Variant of <i>AKT3</i> Defined by Analysis of Alternative Splice Expression in HPV-Positive Oropharyngeal Cancers.
Cancer Res
2017
28146432
Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC.
Oncotarget
2017
28174896
PatternMarkers & GWCoGAPS for novel data-driven biomarkers via whole transcriptome NMF.
Bioinformatics
2017
29123240
DNA methylation regulates TMEM16A/ANO1 expression through multiple CpG islands in head and neck squamous cell carcinoma.
Sci Rep
2017
28947419
Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks.
Cancer Res
2017
28619685
Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancer.
Microbes Infect
2017
28580171
<i>In silico</i> analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia.
Cell Death Discov
2017
26949921
Characterization of functionally active gene fusions in human papillomavirus related oropharyngeal squamous cell carcinoma.
Int J Cancer
2016
27650546
CoGAPS matrix factorization algorithm identifies transcriptional changes in AP-2alpha target genes in feedback from therapeutic inhibition of the EGFR network.
Oncotarget
2016
26884679
Toward Signaling-Driven Biomarkers Immune to Normal Tissue Contamination.
Cancer Inform
2016
26701665
Serum Antibodies to HPV16 Early Proteins Warrant Investigation as Potential Biomarkers for Risk Stratification and Recurrence of HPV-Associated Oropharyngeal Cancer.
Cancer Prev Res (Phila)
2016
25857630
NF-κB and stat3 transcription factor signatures differentiate HPV-positive and HPV-negative head and neck squamous cell carcinoma.
Int J Cancer
2015
26544568
Outlier Analysis Defines Zinc Finger Gene Family DNA Methylation in Tumors and Saliva of Head and Neck Cancer Patients.
PLoS One
2015
26460019
Structural analysis of nucleosomal barrier to transcription.
Proc Natl Acad Sci U S A
2015
24351288
Activation of the NOTCH pathway in head and neck cancer.
Cancer Res
2014
25195578
Correcting transcription factor gene sets for copy number and promoter methylation variations.
Drug Dev Res
2014
24667986
Novel insight into mutational landscape of head and neck squamous cell carcinoma.
PLoS One
2014
24675808
Expression microarray analysis reveals alternative splicing of LAMA3 and DST genes in head and neck squamous cell carcinoma.
PLoS One
2014
24223768
Preferential activation of the hedgehog pathway by epigenetic modulations in HPV negative HNSCC identified with meta-pathway analysis.
PLoS One
2013
22910212
Experimental analysis of the mechanism of chromatin remodeling by RNA polymerase II.
Methods Enzymol
2012
23144906
Suprabasin is hypomethylated and associated with metastasis in salivary adenoid cystic carcinoma.
PLoS One
2012
22792300
Dose-dependent activation of putative oncogene SBSN by BORIS.
PLoS One
2012
1 - 50 of 57
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Johns Hopkins School of Medicine
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The College of New Jersey
Co-authored papers
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William H Westra
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Zubair Khan
University of Texas at Houston Health Science Center
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Patrick K Ha
University of California San Francisco
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Sarah J Wheelan
National Human Genome Research Institute, National Institutes of Health
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Srinivasan Yegnasubramanian
Johns Hopkins University School of Medicine
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Genevieve L Stein-O'Brien
Johns Hopkins School of Medicine
Co-authored papers
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Akihiro Sakai
Tokai University
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Shuling Ren
Beijing Friendship Hospital, Capital Medical University
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University of California San Diego
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