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Author Details

John J O'Shea
National Institute of Arthritis, National Institutes of Health
1984
364
120
PMIDPaper TitleJournal TitlePublished Year
36272581From thymus to tissues and tumors: A review of T-cell biology.J Allergy Clin Immunol2023
36272581From thymus to tissues and tumors: A review of T-cell biology.J Allergy Clin Immunol2023
37559725T cell intrinsic STAT1 signaling prevents aberrant Th1 responses during acute toxoplasmosis.Front Immunol2023
37552767TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis.Sci Signal2023
37957354Microbial ligand-independent regulation of lymphopoiesis by NOD1.Nat Immunol2023
36948491Biologic Versus Small Molecule Therapy for Treating Moderate to Severe Atopic Dermatitis: Clinical Considerations.J Allergy Clin Immunol Pract2023
37256972Variant <i>STAT4</i> and Response to Ruxolitinib in an Autoinflammatory Syndrome.N Engl J Med2023
37443284Transcription factor EGR2 controls homing and pathogenicity of T<sub>H</sub>17 cells in the central nervous system.Nat Immunol2023
37188939Protein kinases: drug targets for immunological disorders.Nat Rev Immunol2023
37540600Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues.Cell Rep2023
37559725T cell intrinsic STAT1 signaling prevents aberrant Th1 responses during acute toxoplasmosis.Front Immunol2023
37957354Microbial ligand-independent regulation of lymphopoiesis by NOD1.Nat Immunol2023
37552767TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis.Sci Signal2023
37540600Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues.Cell Rep2023
37256972Variant <i>STAT4</i> and Response to Ruxolitinib in an Autoinflammatory Syndrome.N Engl J Med2023
37188939Protein kinases: drug targets for immunological disorders.Nat Rev Immunol2023
36948491Biologic Versus Small Molecule Therapy for Treating Moderate to Severe Atopic Dermatitis: Clinical Considerations.J Allergy Clin Immunol Pract2023
37443284Transcription factor EGR2 controls homing and pathogenicity of T<sub>H</sub>17 cells in the central nervous system.Nat Immunol2023
34001528Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory.Cold Spring Harb Perspect Biol2022
36240739The JAK-STAT pathway at 30: Much learned, much more to do.Cell2022
36427325A central role for STAT5 in the transcriptional programing of T helper cell metabolism.Sci Immunol2022
34001528Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory.Cold Spring Harb Perspect Biol2022
34987201Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach.Nat Rev Rheumatol2022
36427325A central role for STAT5 in the transcriptional programing of T helper cell metabolism.Sci Immunol2022
36240739The JAK-STAT pathway at 30: Much learned, much more to do.Cell2022
34987201Janus kinase-targeting therapies in rheumatology: a mechanisms-based approach.Nat Rev Rheumatol2022
33237303Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma.J Exp Med2021
34180156A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?Arthritis Rheumatol2021
33841440Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes.Front Immunol2021
33574619BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8<sup>+</sup> T cells.Nat Immunol2021
34099646Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus.Nat Commun2021
33939926Immunology Lessons from the SARS-CoV-2 Pandemic.Annu Rev Immunol2021
33658708Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8<sup>+</sup> T cells.Nat Immunol2021
33657395MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23.Immunity2021
33930196JAK inhibitors: Ten years after.Eur J Immunol2021
34301840Cutting Edge: Steroid Responsiveness in Foxp3<sup>+</sup> Regulatory T Cells Determines Steroid Sensitivity during Allergic Airway Inflammation in Mice.J Immunol2021
33237303Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma.J Exp Med2021
34625141JAK-STAT signaling in human disease: From genetic syndromes to clinical inhibition.J Allergy Clin Immunol2021
34623903Cholesterol 25-hydroxylase is a metabolic switch to constrain T cell-mediated inflammation in the skin.Sci Immunol2021
34644563PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8<sup>+</sup> T cells at the expense of central memory.Cell Rep2021
34586363MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination.J Exp Med2021
35056105Jakinibs of All Trades: Inhibiting Cytokine Signaling in Immune-Mediated Pathologies.Pharmaceuticals (Basel)2021
33574619BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8<sup>+</sup> T cells.Nat Immunol2021
33841440Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes.Front Immunol2021
33930196JAK inhibitors: Ten years after.Eur J Immunol2021
33658708Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8<sup>+</sup> T cells.Nat Immunol2021
33657395MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23.Immunity2021
35056105Jakinibs of All Trades: Inhibiting Cytokine Signaling in Immune-Mediated Pathologies.Pharmaceuticals (Basel)2021
34644563PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8<sup>+</sup> T cells at the expense of central memory.Cell Rep2021
34586363MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination.J Exp Med2021
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Collaborators

Co-authored papers 76
National Institute of Arthritis and Musculoskeletal and Skin Diseases
Co-authored papers 56
University of Miami Miller School of Medicine
Co-authored papers 32
Co-authored papers 27
National Eye Institute, National Institutes of Health
Co-authored papers 20
University of Texas Southwestern Medical Center
Co-authored papers 12
National Cancer Institute
Co-authored papers 12
Institute of Immunity, Stanford University School of Medicine
Co-authored papers 11
Co-authored papers 10
Howard Hughes Medical Institute
Co-authored papers 10
National Institute of Allergy and Infectious Diseases
Co-authored papers 9
Co-authored papers 8
Co-authored papers 8
National Cancer Institute, National Institutes of Health (NIH)
Co-authored papers 6
Pritzker School of Medicine, University of Chicago
Co-authored papers 5
Center for Cancer Research, National Cancer Institute
Co-authored papers 5
Co-authored papers 5
Co-authored papers 5
Columbia University
Co-authored papers 5
National Institute of Allergy and Infectious Diseases
Co-authored papers 5
Co-authored papers 3
University Hospital Southampton
Co-authored papers 3
Co-authored papers 3
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 3
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Merck & Co., Inc.
Co-authored papers 3
Co-authored papers 3
National Institute of Arthritis
Co-authored papers 3
Center for Cellular Engineering, NIH Clinical Center, National Institutes of Health
Co-authored papers 2
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 2